Segment Information

12 Months Ended

Sep. 30, 2025

The Company’s Chief Executive Officer has been identified as the chief operating decision maker (CODM). The CODM reviews the Company’s operating results on a consolidated basis for purposes of allocating resources and evaluating financial performance. Specifically, the CODM evaluates the Company’s financial performance and decides how to allocate resources based on consolidated net income (loss), which enables the CODM to assess both the overall level of resources available and optimize distribution of resources across functions, product lines, regions and research and development programs in line with our long-term corporate-wide strategic goals. The CODM also reviews disaggregated revenue by product line, geographic regions, and industry (see Note 3).

The following table presents entity-wide significant expense categories and net loss details provided to the CODM:


	Year ended September 30,
(In thousands)	2025		2024		2023
Revenues	$	376,572	$	312,974	$	245,109
Costs and expenses:
Cost of revenues[1]	$	161,545	$	154,030	$	132,417
Research and development expenses[1]	69,950		76,605		88,937
Selling, general and administrative expenses[1]	192,024		175,883		171,070
Depreciation and amortization	24,853		31,432		29,310
Stock-based compensation expense	64,459		50,925		30,278
Restructuring and other costs	—		—		9,384
Change in fair value of contingent considerations and holdbacks	—		—		(5,913)
Impairment of long-lived assets	—		44,930		6,785
Total costs and expenses	$	512,831	$	533,805	$	462,268
Loss from operations	$	(136,259)	$	(220,831)	$	(217,159)
Gain on sale of business	$	48,847	$	—	$	—
Interest income	11,364		15,344		14,365
Other income (expense), net	(903)		(2,679)		(672)
Income (loss) before income taxes	$	(76,951)	$	(208,166)	$	(203,466)
Income tax expense	(719)		(560)		(1,152)
Net loss	$	(77,670)	$	(208,726)	$	(204,618)

[1] Excludes depreciation and amortization and stock-based compensation expense

Asset information is not regularly provided to the CODM for assessing performance and allocating resources other than consolidated cash and cash equivalents and short-term investments, which can be found on our Consolidated Balance Sheets.

- Definition

The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments.

+ References

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+ Details

Twist Bioscience Corp 10-K