v3.25.1

Consolidated Statements of Stockholders’ Equity (Deficit) - USD ($) shares in Thousands, $ in Thousands	Total	Common stock	Additional paid-in capital	Accumulated other comprehensive loss	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2022		4,146
Beginning balance at Dec. 31, 2022	$ 134,333	$ 830	$ 4,185,988	$ (4,070)	$ (4,048,415)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Vesting of restricted stock units (in shares)		55
Vesting of restricted stock units	(196)	$ 10	(206)
Exercise of stock options (in shares)		1
Exercise of stock options	92		92
Purchase of common stock under ESPP (in shares)		7
Purchase of common stock under ESPP	429	$ 2	427
Issuance of common stock (in shares)		5,317
Issuance of common stock	248,367	$ 1,063	247,304
Exercise of warrants (in shares)		113
Stock-based compensation	21,151		21,151
Other comprehensive income (loss)	2,274			2,274
Net loss	$ (211,913)				(211,913)
Ending balance (in shares) at Dec. 31, 2023	9,639	9,639
Ending balance at Dec. 31, 2023	$ 194,537	$ 1,905	4,454,756	(1,796)	(4,260,328)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Vesting of restricted stock units (in shares)		82
Vesting of restricted stock units	$ (2)	$ 16	(18)
Exercise of stock options (in shares)	0
Purchase of common stock under ESPP (in shares)		7
Purchase of common stock under ESPP	$ 100	$ 2	98
Issuance of warrants	626		626
Stock-based compensation	14,257		14,257
Other comprehensive income (loss)	(337)			(337)
Net loss	$ (240,715)				(240,715)
Ending balance (in shares) at Dec. 31, 2024	9,728	9,728
Ending balance at Dec. 31, 2024	$ (31,534)	$ 1,923	$ 4,469,719	$ (2,133)	$ (4,501,043)

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