Cover - USD ($)	12 Months Ended
Cover - USD ($)	Dec. 31, 2024	Apr. 11, 2025	Jun. 28, 2024
Cover [Abstract]
Document Type	10-K/A
Amendment Flag	true
Amendment Description	This Amendment No. 1 to the Annual Report on Form 10-K (this Amendment) amends the Annual Report on Form 10-K for the fiscal year ended December 31, 2024, originally filed on March 21, 2025 (the Original Filing) by Chimerix, Inc., a Delaware corporation (Chimerix or the Company). As previously disclosed in the Company's Current Report on Form 8-K filed with the SEC on March 5, 2025, on March 4, 2025, the Company entered into an Agreement and Plan of Merger with Jazz Pharmaceuticals Public Limited Company, an Irish public limited company (Jazz), pursuant to which Jazz has agreed to acquire Chimerix for $8.55 per share in cash, for a total consideration of approximately $935 million, by means of a tender offer followed by a merger (the Merger). The completion of the Merger remains subject to customary closing conditions, including the tender of a majority of the outstanding shares of Chimerix's voting common stock and other conditions.
Document Annual Report	true
Document Transition Report	false
Document Period End Date	Dec. 31, 2024
Document Fiscal Period Focus	FY
Document Fiscal Year Focus	2024
Current Fiscal Year End Date	--12-31
Entity File Number	001-35867
Entity Registrant Name	Chimerix, Inc.
Entity Central Index Key	0001117480
Entity Tax Identification Number	33-0903395
Entity Incorporation, State or Country Code	DE
Entity Address, Address Line One	2505 Meridian Parkway
Entity Address, Address Line Two	Suite 100
Entity Address, City or Town	Durham
Entity Address, State or Province	NC
Entity Address, Postal Zip Code	27713
City Area Code	919
Local Phone Number	806-1074
Title of 12(b) Security	Common Stock, par value $0.001 per share
Trading Symbol	CMRX
Security Exchange Name	NASDAQ
Entity Well-known Seasoned Issuer	No
Entity Voluntary Filers	No
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	false
Entity Shell Company	false
Entity Public Float			$ 74,314,290
Entity Common Stock, Shares Outstanding		93,803,846
Documents Incorporated by Reference [Text Block]	None
ICFR Auditor Attestation Flag	false
Document Financial Statement Error Correction [Flag]	false
Auditor Firm ID	42
Auditor Name	Ernst & Young LLP
Auditor Location	Raleigh, North Carolina

CHIMERIX INC 10-K/A