UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 4)*

Adesto Technologies Corporation

(Name of Issuer)

Common Stock, $0.0001 par value

(Title of Class of Securities)

00687D 101

(CUSIP Number)

Mark McDonnell

ARCH Venture Corporation

8755 W. Higgins Road Suite 1025

Chicago, IL 60631

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

June 29, 2020

(Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ☐

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7 for other parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Persons who respond to the collection of information contained in this form are not
required to respond unless the form displays a currently valid OMB control number.

CUSIP No. 00687D 101

13D

Page 2 of 5 Pages

Schedule 13D

Item 1.

Security and Issuer.

This Amendment No. 4 (the “Amendment No. 4”) to the Schedule 13D filed on November 10, 2015 (the “Original 13D”), as amended by Amendment No. 1 (the “Amendment No. 1”) to the Original 13D filed on July 7, 2017, Amendment No. 2 (the “Amendment No. 2”) to the Original 13D filed on August 28, 2018, and Amendment No. 3 (the Amendment No. 3”) to the Original 13D filed on January 21, 2020, relating to the Common Stock, $0.0001 par value per share (the “Common Stock”), of Adesto Technologies Corporation (the “Issuer”) having its principal executive office at 3600 Peterson Way, Santa Clara, CA 95054, amends the Original 13D as set forth herein.

Certain terms used, but not defined, in this Amendment No. 4 shall have the meanings assigned thereto in the Original 13D (as amended by Amendment No. 1, Amendment No. 2 and Amendment No. 3). Except as specifically provided herein, this Amendment No. 4 does not modify any of the information previously reported in the Original 13D, Amendment No. 1, Amendment No. 2 or Amendment No. 3.

Item 2.

Identity and Background.

(a)

This statement is being filed by: (1) ARCH Venture Fund VI, L.P. (“ARCH Venture Fund VI”), (2) ARCH Venture Partners VI, L.P. (“AVP VI LP”), which is the sole general partner of ARCH Venture Fund VI, (3) ARCH Venture Partners VI, LLC (“AVP VI LLC”), which is the sole general partner of AVP VI LP, (4) Clinton Bybee (“Bybee”), (5) Keith Crandell (“Crandell”), and (6) Robert Nelsen (“Nelsen” and, together with Bybee and Crandell, collectively, the “Managing Directors” and each individually, a “Managing Director”). Each of the individuals and entities above shall be referred to herein individually as a “Reporting Person” and collectively as the “Reporting Persons”.

(b)

The business address of each of the Reporting Persons is 8755 West Higgins Road, Suite 1025, Chicago, IL, 60631.

(c)

The principal business of ARCH Venture Fund VI is to invest and assist in developmental and emerging businesses located principally in the United States. The principal business of AVP VI LP is to act as the general partner of ARCH Venture Fund VI. The principal business of AVP VI LLC is to act as the general partner of AVP VI LP. The principal business of each of the Managing Directors is to act as managing directors of AVP VI LLC and a number of affiliated partnerships with similar businesses.

(d)

During the five years prior to the date hereof, none of the Reporting Persons has been convicted in a criminal proceeding.

(e)

During the five years prior to the date hereof, none of the Reporting Persons has been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction ending in a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, Federal or State securities laws or finding any violation with respect to such laws.

(f)

Each of ARCH Venture Fund VI and AVP VI LP is a Delaware limited partnership. AVP VI LLC is a Delaware limited liability company. Each of the Managing Directors is a United States citizen.

CUSIP No. 00687D 101

13D

Page 3 of 5 Pages

Item 4.

Purpose of Transaction.

Not Applicable

Item 5.

Interest in Securities of the Issuer.

Each of the Reporting Persons has ceased to beneficially own five percent (5%) or more of the Issuer’s outstanding Common Stock.

Item 7.

Material to be Filed as Exhibits.

Exhibit 1 – Agreement regarding filing of joint Schedule 13D.

CUSIP No. 00687D 101

13D

Page 4 of 5 Pages

Signature

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: July 10, 2020

ARCH Venture Fund VI, L.P.

By: ARCH Venture Partners VI, L.P.

its General Partner

By: ARCH Venture Partners VI, LLC

its General Partner

By: _____________*____________

Managing Director

ARCH Venture Partners VI, L.P.

By: ARCH Venture Partners VI, LLC

its General Partner

By: _____________*____________

Managing Director

ARCH VENTURE PARTNERS VI, LLC

By: _____________*____________

Managing Director

Clinton Bybee

Keith Crandell

Robert Nelsen

* By: /s/ Mark McDonnell

Mark McDonnell as Attorney-in-Fact

* This Amendment No. 4 to Schedule 13D was executed by Mark McDonnell pursuant to a Power of Attorney filed as Exhibit 24 to the Form 3 relating to the beneficial ownership of shares of Fate Therapeutics, Inc. (FATE) by the Reporting Persons filed with the Securities Exchange Commission on September 30, 2013 and incorporated herein in its entirety by reference.

CUSIP No. 00687D 101

13D

Page 5 of 5 Pages

Exhibit 1

AGREEMENT OF JOINT FILING

Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13D need be filed with respect to the ownership by each of the undersigned of shares of Common Stock of Adesto Technologies Corporation.

This Agreement may be executed in any number of counterparts, each of which shall be deemed an original.

Date: July 10, 2020

ARCH Venture Fund VI, L.P.

By: ARCH Venture Partners VI, L.P.

its General Partner

By: ARCH Venture Partners VI, LLC

its General Partner

By: _____________*____________

Managing Director

ARCH Venture Partners VI, L.P.

By: ARCH Venture Partners VI, LLC

its General Partner

By: _____________*____________

Managing Director

ARCH VENTURE PARTNERS VI, LLC

By: _____________*____________

Managing Director

Clinton Bybee

Keith Crandell

Robert Nelsen

* By: /s/ Mark McDonnell

Mark McDonnell as Attorney-in-Fact

ADESTO TECHNOLOGIES Corp SC 13D/A