Income Taxes - Schedule of Provision for Income Taxes and Effective Tax rates (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Income Tax Disclosure [Abstract]
Income (loss) before provision for income taxes	$ 1,298.8	$ 1,224.1	$ 3,312.2	$ (888.0)
Provision for income taxes	$ 215.9	$ 178.7	$ 550.1	$ 560.6
Effective tax rate	16.60%	14.60%	16.60%	(63.10%)

Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest.

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+ Details

- Definition

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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+ Details

VERTEX PHARMACEUTICALS INC / MA 10-Q