UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

~~WASHINGTON~~Washington, D.C. 20549

FORM 6-K

~~REPORT~~Report OFof ~~FOREIGN~~Foreign ~~PRIVATE~~Private ~~ISSUER~~Issuer

~~PURSUANT~~Pursuant TOto ~~RULE~~Rule 13a-16 ORor 15d-16 of

~~UNDER~~the ~~THE~~Securities ~~SECURITIES~~Exchange ~~EXCHANGE~~Act ~~ACT~~of OF 1934

For the month of ~~May~~August 2025

Commission File Number 001-41231

TC BIOPHARM (HOLDINGS) PLC

(Translation of registrant’s name into English)

Maxim 1, 2 Parklands Way

Holytown, Motherwell, ML1 4WR

Scotland, United Kingdom

+44 (0) 141 433 7557

(Address of Principal Executive Offices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

☒ Form 20-F

☐ Form 40-F

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ____ ☐

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ____ ☐

~~Submission~~Notice of ~~Matters~~Annual toGeneral ~~a Vote of Shareholders~~Meeting

~~The~~On ~~general~~August ~~meeting~~5, 2025, TC BioPharm (Holdings) plc (“TC BioPharm” or the “Company”) issued notice of ~~shareholders~~the Company’s Annual General Meeting, a copy of which ~~was~~is ~~announced~~furnished as Exhibit 99.1 to this Current Report on ~~May~~Form 6,-K. ~~2025,~~The ~~was~~Company’s ~~convened~~Annual inGeneral Meeting ~~accordance~~will ~~with~~be ~~the~~held ~~Articles~~at ofMaxim ~~association~~1, of2 ~~the Company~~Parklands Way, Holytown, Motherwell, ML1 4WR, United Kingdom on ~~May~~August 2229, 2025; ~~and,~~at in02:00 p.m. ~~line~~British ~~with~~Summer ~~the~~Time. ~~powers~~Furnished ~~vested~~(i) inas ~~the~~Exhibit ~~chairman~~99.2 ofto ~~the~~this ~~meeting~~Current ~~with~~Report ~~the~~on ~~consent~~Form of6-K is the ~~meeting~~Form ,of Proxy for the ~~general meeting~~Bank ~~was~~of ~~adjourned~~New York byMellon (the ~~chairman indefinitely~~“Depositary”), (ii) as Exhibit 99.3 to athis ~~time~~Current ~~and~~Report ~~place~~on toForm be6-K ~~determined~~is ~~and~~the ~~announced~~Voting Instruction Form for holders of American Depositary Shares (“ADSs”).

~~Signature~~Shareholders of record as of 05:00 p.m Eastern Standard Time on August 1, 2025 are entitled to vote at the Meeting. The Company’s holders of ADSs are not shareholders of record, but, under the terms of the Depositary Agreement between the Company, the Depositary and the ADS holders, they will be able to vote by proxy ahead of the meeting, before 12:00 p.m. Eastern Standard Time on August 25, 2025.

INDEX TO EXHIBITS

Number		Description
99.1		Notice of Annual General Meeting.
99.2		Form of Proxy.
99.3		Voting Instruction Form for holders of American Depositary Shares.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

	TC BIOPHARM (HOLDINGS) PLC
	By:	/s/ Martin Thorp
Date: August 5, 2025	By:	/s/ Martin Thorp
	Name:	Martin Thorp
		Martin Thorp
	Title:	Chief Financial Officer
		Chief Financial Officer
Date: May 27, 2025

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