UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-K

~~[X]~~x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the fiscal ~~year~~years ended December 31, ~~2014~~2016 and 2015

~~[ ]~~¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from ___________ to ___________

Commission File No. 000-54626

SIGNAL ADVANCE, INC. (Exact name of registrant as specified in its charter)

(Exact name of registrant as specified in its charter)

Texas

8731

376-0373052

(State or Other Jurisdiction of

Incorporation or Organization)

(Primary Standard Industrial

Classification Number)

(IRS Employer

Identification Number)

Texas		8731		76-0373052
(State or Other Jurisdiction of Incorporation or Organization)		(Primary Standard Industrial Classification Number)		(IRS Employer Identification Number)

2520 County Road 81

Rosharon, Texas 77583

(713) 510-7445

(Address and telephone number of principal executive offices)

Securities registered pursuant to Section 12(b) of the Act: None

Securities registered pursuant to Section 12(g) of the Act: None

Indicate by check mark whether the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes ~~[ ]~~¨ No ~~[X]~~x

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes ~~[ ]~~¨ No ~~[X]~~x

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for shorter period that the registrant as required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ~~[X]~~x No ~~[ ]~~¨

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of registrant'’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. Yes ~~[ ]~~¨ No ~~[X]~~x

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, or a non-accelerated filer. See definition of "“accelerated filer and large accelerated filer"” in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer [¨ ] Accelerated filer [¨ ] Non-accelerated filer [¨ ] Smaller reporting company ~~[X]~~x Emerging growth company x

~~Indicate~~If an emerging growth company, indicate by check mark ~~whether~~if the registrant ishas aelected ~~shell~~not ~~company~~to ~~(as~~use ~~defined~~the inextended ~~Rule~~transition ~~12b-2~~period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act). ¨

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act) Yes ~~[ ]~~¨ No ~~[X]~~x

The market value of the common equity held by non-affiliates: $10411,~~727,982~~865 based on a $20.1008 closing price of the registrant'’s common stock as of the last business day of the registrant'’s year ended December 31, ~~2014~~2016.

As of ~~March~~December 2431, ~~2015~~2016, the registrant had 1012,~~305~~407,~~077~~342 shares of common stock ~~are~~ issued and outstanding.

As of the date of this report, the Issuer had 16,435,342 shares of common stock issued and outstanding.

TABLE OF CONTENTS

PART I
ITEM 1	Description of Business	4	4
ITEM 1A	Risk Factors	8	8
ITEM 2	Description of Property	8	8
ITEM 3	Legal Proceedings	8	8
ITEM 4	Submission of Matters to a Vote of Security Holders	8	8
PART II
ITEM 5	Market for Common Equity and Related Stockholder Matters	9	9
ITEM 6	Selected Financial Data	10	10
ITEM 7	Management'’s Discussion and Analysis of Financial Condition and Results of Operations	10	10
ITEM 7A	Quantitative and Qualitative Disclosures about Market Risk	14	13
ITEM 8	Financial Statements and Supplementary Data	15	14
ITEM 9	Changes In and Disagreements with Accountants on Accounting and Financial Disclosure	29	15
ITEM 9A (T)	Controls and Procedures	29	15
PART III
ITEM 10	Directors, Executive Officers, Promoters and Control Persons of the Company	30	17
ITEM 11	Executive Compensation	31	19
ITEM 12	Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters	32	20
ITEM 13	Certain Relationships and Related Transactions	33	21
ITEM 14	Principal Accountant Fees and Services	34	21
PART IV
ITEM 15	Exhibits	35	22

32 Table of Contents

FORWARD-LOOKING STATEMENTS:

This Annual Report on Form 10-K including our Management’s Discussion and Analysis contains not only statements that are historical facts, but also statements that are forward-looking (within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934).

Forward-looking statements are, by their very nature, uncertain and risky. These risks and uncertainties include the Company’s limited operating history; its limited financial resources; the success of our fundraising efforts; our ability to meet our obligations, continue as a going concern or realize on our assets, if necessary to meet liabilities; international, national and local general economic and market conditions; demographic changes; our ability to achieve, sustain, manage or forecast growth; our failure to correctly anticipate market trends; our ability to successfully make and integrate acquisitions; risks related to new product development and introduction; competition including the activities of competitors and the presence of new or additional competition; the failure to gain and/or loss of significant customers or suppliers; fluctuations and difficulty in forecasting operating results; changes in business strategy or development plans; business disruptions; the ability to attract and retain qualified personnel; the ability to protect technology and obtain and/or maintain key licensing arrangements, joint ventures and partnerships; and other risks that might be detailed from time to time in our filings with the Securities and Exchange Commission (the “SEC”).

The following discussion should be read in conjunction with our financial statements, including the notes thereto, appearing elsewhere in this annual report. This report may contain forward-looking statements which relate to future events or our future financial performance. These statements often can be identified by the use of terms such as “may,” “will,” “expect,” “believe,” “anticipate,” “estimate,” “plan,” “approximate” or “continue,” or the negative thereof. We intend that such forward-looking statements be subject to the safe harbors for such statements. We wish to caution readers not to place undue reliance on any such forward-looking statements, which speak only as of the date made. Any forward-looking statements represent management’s best judgment as to what may occur in the future. However, forward-looking statements are subject to risks, uncertainties and important factors beyond our control that could cause actual results and events to differ materially from historical results of operations and events and those presently anticipated or projected. We disclaim any obligation subsequently to revise any forward-looking statements to reflect events or circumstances after the date of such statement or to reflect the occurrence of anticipated or unanticipated events. Unless the context requires otherwise, the terms ‘Company,’ ‘SA,’ ‘we,’ ‘our,’ and ‘us’ refer to Signal Advance Inc., a Texas corporation formed on June 4, 1992. Our audited financial statements are stated in United States Dollars and are prepared in accordance with U.S. Generally Accepted Accounting Principles.

The following business and financial discussion should be read in conjunction with our financial statements, including the notes thereto, appearing in this filing.

Table of Contents

PART I

~~Item 1. Description of Business~~Introduction

~~FORWARD~~This annual report on Form 10-~~LOOKING~~K ~~STATEMENTS~~is a comprehensive filing for the fiscal years ended December 31, 2016 and 2015. It is being filed by us in order to become current in our filing obligations under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). This is our first periodic filing since the quarter ended September 20, 2015. Included in this report are the audited financial statements that have not been included in annual reports on Form 10-K since the fiscal year ended December 31, 2014, as well as summarized quarterly financial information for each of the quarters ended (i) March 30, June 30 and September 30, 2016.

~~The~~This ~~following~~annual ~~discussion~~report should be read together and in ~~conjunction~~connection with ~~our financial statements, including~~ the ~~notes~~other ~~thereto,~~reports ~~appearing~~filed ~~elsewhere in this annual report. This report may contain forward-looking statements which relate to future events or our future financial performance. These statements often can be identified~~ by ~~the~~us ~~use~~with ~~of terms such as "may," "will," "expect," "believe," "anticipate," "estimate," "plan," "approximate" or "continue," or~~ the ~~negative thereof~~SEC. WeIn ~~intend that such forward-looking statements be subject to~~ the ~~safe~~interest ~~harbors~~of ~~for~~complete ~~such~~and ~~statements.~~accurate ~~We wish to caution readers not to place undue reliance on any such forward-looking statements~~disclosure, ~~which~~we ~~speak~~have ~~only~~included ascurrent ofinformation ~~the date made. Any forward-looking statements represent management's best judgment as to what may occur~~ in ~~the~~this ~~future.~~annual ~~However,~~report ~~forward-looking~~for ~~statements~~all ~~are~~material ~~subject~~events ~~to risks, uncertainties~~ and ~~important~~developments ~~factors beyond our control~~ that ~~could~~have ~~cause~~taken ~~actual~~place ~~results~~since ~~and~~September ~~events~~31, to2015 ~~differ~~through materially from historical results of operations and events and those presently anticipated or projected. We disclaim any obligation subsequently to revise any forward-looking statements to reflect events or circumstances after the date of ~~such~~filing ~~statement or to reflect the occurrence~~ of ~~anticipated~~this orannual ~~unanticipated~~report ~~events.~~with ~~Unless~~ the ~~context requires otherwise, the terms 'Company,' 'SAI,' 'SA,' 'we,' 'our,' and 'us' refer to Signal Advance Inc~~SEC.~~, a Texas corporation formed on June 4, 1992. Our audited financial statements are stated in United States Dollars and are prepared in accordance with U.S. Generally Accepted Accounting Principles.~~

~~OVERVIEW: Signal~~Item ~~Advance, Inc~~1. ~~(SAI)~~Description ~~is a technology development firm that has been developing its proprietary Signal Advance Technology (SAT) which may significantly reduce signal detection delays associated with a variety~~ of physical sensors and thereby improve performance in control, intervention, and/or signal transmission systems. The Company has developed and tested SA circuit designs and discrete circuit prototypes for a range of signal characteristicsBusiness

~~CHALLENGE~~OVERVIEW: In ~~interventional~~Signal ~~medical devices or non-medical responsive control and signal transmission systems~~Advance, ~~delays in detection, processing and response to various signals negatively affects overall performance~~Inc. ~~For certain types of biomedical signals~~ (~~e.g. heart, brain~~SA) ~~the~~is ~~greater~~a ~~the~~technology ~~delay~~development infirm ~~responding~~that tohas ~~anomalous~~been ~~signals,~~developing ~~the~~its ~~more~~proprietary ~~difficult~~Signal itAdvance isTechnology towhich ~~successfully~~may ~~intervene~~significantly inreduce ~~order~~signal todetection ~~contain~~delays orassociated ~~limit~~with a ~~pathological~~variety ~~process~~of ~~such~~physical ~~as cardiac fibrillation or an epileptic seizure. The earlier the intervention is initiated~~sensors, ~~the~~thereby ~~greater~~improving ~~the~~response ~~probability~~time ofand ~~success. In~~performance ~~non-medical~~in ~~applications (e.g. industrial process, equipment, engine~~ control, ~~military)~~intervention, ~~control~~and/or ~~response~~ signal transmission ~~delays~~systems. ~~impact~~The ~~performance~~Company ~~effecting~~has ~~safety,~~developed ~~product~~and ~~yield,~~tested ~~fuel~~SA ~~efficiency~~circuit designs and ~~waste/emissions.~~discrete Incircuit ~~military~~prototypes ~~applications,~~for ~~signal~~a ~~detection~~range ~~and~~of ~~response~~signal ~~delays affect reaction effectiveness~~characteristics.

~~SOLUTION~~CHALLENGE: In ~~most~~interventional ~~electronic~~medical ~~circuits,~~devices or non-medical responsive control and signal ~~output~~transmission issystems, ~~delayed~~delays ~~relative~~in todetection, ~~the~~processing ~~input~~and asresponse itto ~~traverses~~various ~~the~~signals ~~circuitry~~negatively affects overall performance. ~~When~~For acertain ~~signal~~types isof ~~applied~~biomedical tosignals an(e.g. SAheart, ~~circuit~~brain) the ~~output~~greater ~~signal~~the isdelay ~~advanced~~ in ~~time~~responding ~~relative~~ to anomalous signals, the ~~input~~more ~~using~~difficult ~~the~~it ~~advance~~is ~~portion~~to ofsuccessfully ~~the~~intervene ~~waveform~~in ~~and~~order ~~not~~to ~~depending~~contain onor ~~the~~limit ~~wave~~a ~~velocity~~pathological ~~form~~process ofsuch ~~the~~as ~~signal~~cardiac ~~that~~fibrillation ~~are~~or ~~conventionally~~an ~~used~~epileptic seizure. The earlier the intervention is initiated, ~~thus~~the greater the ~~term~~probability ~~'Signal~~of ~~Advance'~~success. In ~~other~~non-medical ~~words~~applications (e.g. industrial process, ~~the~~equipment, ~~output~~engine control, military), control response signal ~~emerges~~transmission ~~before~~delays ~~the~~impact ~~complete~~performance ~~detection~~effecting ofsafety, ~~the~~product ~~input~~yield, fuel efficiency and waste/emissions. In military applications, signal detection and response delays affect reaction effectiveness.

4SOLUTION: In most electronic circuits, signal output is delayed relative to the input as it traverses the circuitry. When a signal is applied to an SA circuit the output signal is advanced in time relative to the input using the advance portion of the waveform and not depending on the wave velocity form of the signal that are conventionally used, thus the term ‘Signal Advance’. In other words, the output signal emerges before the complete detection of the input signal.

The temporal advance achieved using ~~SAT~~SA technology can potentially offset signal detection and processing delays and, thereby, improve response time. Further, we believe that ~~SAT~~SA technology could be implemented in conjunction with other approaches (e.g. faster electronics) to further reduce these response delays to further improve ~~system~~ performance. ~~SAT~~SA technology may also enable the development of novel signal transmission, and control or interventional approaches.

Prototype ~~SAT~~SA circuit designs were used to temporally-advance the detection of analog test signals and bioelectric (cardiac) signals in a dissertation study completed by Dr. Hymel (~~SAI~~Company Founder/~~president~~President) at the University of Texas Health Science Center in the Texas Medical Center, Houston Texas. The study results were later published in a peer-reviewed feature article which appeared in the IEEE Circuits and Systems magazine.

~~MARKET: SAI~~4 ~~identified~~Table ~~multiple classes~~ of sensors with signal characteristics which may be suitable for the application of SAT, and thus, a variety of potential licensing targets. The markets/industries include biomedical (e.g. cardiac rhythm management, neurostimulation) and commercial, industrial, communications, transportation and military applications (e.g. process control, signal transmission, engine control, vehicular/flight control, accident avoidance, and weaponry).Contents

InMARKET: ~~interventional medical devices, SAT could reduce response delays and improve performance.~~ The ~~improved~~Company ~~performance~~has ~~translates~~identified ~~directly~~multiple toclasses ~~increased value, providing a significant opportunity for revenue generation. Examples~~ of ~~non-biomedical~~sensors ~~applications~~with ~~include~~signal ~~transportation,~~characteristics in which ~~SAT~~may ~~could~~be ~~improve~~suitable ~~accident~~for ~~avoidance,~~the ~~safety/security,~~application ~~engine~~of ~~performance~~SA ~~and vehicular control~~technology, and thus, ~~improve~~a ~~fuel~~variety ~~economy~~of ~~and~~potential ~~save~~licensing ~~lives~~targets. In ~~high~~The ~~performance~~markets/industries ~~aircraft~~include ~~engines,~~biomedical ~~SAT~~(e.g. ~~might~~cardiac ~~increase~~rhythm ~~stability~~management, ~~reduce~~neurostimulation) ~~stall margins improve performance~~ and ~~fuel~~commercial, ~~efficiency.~~industrial, ~~Industrial~~communications, ~~examples~~transportation ~~include~~and ~~improved~~military ~~compressor~~applications ~~performance~~(e.g. ~~and~~process ~~increased~~control, ~~petrochemical~~signal ~~yields.~~transmission, Inengine ~~military applications~~control, ~~SAT~~vehicular/flight ~~could~~control, ~~enhance~~accident ~~response~~avoidance, ~~effectiveness~~and weaponry).

In interventional medical devices, SA technology could reduce response delays and improve performance. The ~~addressable~~improved ~~markets~~performance ~~are~~translates ~~estimated~~directly to beincreased invalue, ~~the~~providing ~~billions~~a significant opportunity for revenue generation. Examples of ~~dollars~~non-biomedical applications include transportation, in which SA technology could improve accident avoidance, safety/security, engine performance and vehicular control, and thus improve fuel economy and save lives. AsIn ~~with~~high ~~any~~performance ~~new~~aircraft orengines, ~~disruptive~~SA technology might increase stability, ~~recognition~~reduce stall margins improve performance and ~~acceptance~~fuel ~~will~~efficiency. ~~gain~~Industrial ~~momentum~~examples ~~over~~include ~~time~~improved compressor performance and increased petrochemical yields. In military applications, SA technology could enhance response effectiveness.

~~INTELLECTUAL PROPERTY:~~ The ~~following~~addressable ~~table~~markets ~~lists~~are estimated to be in the ~~patent~~billions ~~applications~~of dollars. As with any new or disruptive technology, recognition and ~~issued~~acceptance ~~patents:~~will gain momentum over time.

Patent Office	Patent or Appl. No.	Status
United States	8452544	Issued May 2013
China	ZL 200880015288.2	Issued Nov. 2012
Europe	EP 08 75 4879.8	Issued Apr. 2014
Mexico	MX/A/2009/00921	Under examination
India	3465/KOLNP/2009	Not yet examined

INTELLECTUAL PROPERTY: The following table lists the patent applications and issued patents:

Additional patent submissions related to specific applications, SA circuit configurations, and signal processing techniques to improve signal fidelity are being drafted.

Patent Office	Patent or Appl. No.	Status
United States	8452544	Issued May 2013
China	ZL 200880015288.2	Issued November 2012
Mexico	325278	Issued April 2014
Europe	EP 2137817	Issued January, 2017
India	3465/KOLNP/2009	Under examination

~~COMPETITION: Indirect~~Additional ~~competition~~patent ~~exists~~submissions asrelated ~~in the form of ever faster electronics used~~ to ~~improve~~specific ~~signal detection and processing performance. In addition~~applications, ~~alternate~~SA ~~control~~circuit ~~strategies~~configurations, ~~(e.g. predictive feedback~~ and ~~feed-forward)~~signal ~~are~~processing ~~often~~techniques ~~used~~ to improve ~~performance~~signal ~~but~~fidelity ~~also~~as ~~have~~well ~~significant~~as ~~drawbacks. Faster electronics alone will reduce, but never eliminate, circuit delays. For~~ a ~~number~~Neural ofTraining ~~applications,~~application ~~some~~are ofbeing ~~these techniques may be adequate~~considered. ~~SAT, used in conjunction with all of these methods, could further improve performance.~~

5COMPETITION: Indirect competition exists as in the form of ever faster electronics used to improve signal detection and processing performance. In addition, alternate control strategies, (e.g. predictive feedback and feed-forward) are often used to improve performance but also have significant drawbacks. Faster electronics alone will reduce, but never eliminate, circuit delays. For a number of applications, some of these techniques may be adequate. SA technology, used in conjunction with all of these methods, could further improve performance.

REVENUE GENERATION: While the addressable markets are in the billions, it is expected that many licensees will require exclusivity which would limit ~~SAI~~the Company to a single license in a given application area. Therefore, ~~SAI~~SA will target multiple application areas to generate revenue. Revenue is generated by: 1) licensing intellectual property to product manufacturers, 2) consulting with licensees on implementation of the technology in target applications, and 3) participating in joint ventures.

MARKETING STRATEGY: To gain exposure and acceptance of ~~SAT~~SA technology, the Company will participate in trade shows, present in scientific and technical meetings and publish application-specific articles. ~~SAI'~~ SA’s marketing approach includes the following steps: 1) identify application targets, 2) develop application-specific ~~SAI~~SA circuitry, 3) demonstrate performance improvement, 4) protect the intellectual property, 5) approach target manufacturer(s) and 6) secure licensing/consulting agreements.

~~Target application selection is based on: 1) intervention/control impact, 2) signal characteristics, 3) market size, 4) supplier market share,~~ 5) ~~competition,~~Table ~~and~~of ~~6) regulations.~~Contents

Target application selection is based on: 1) intervention/control impact, 2) signal characteristics, 3) market size, 4) supplier market share, 5) competition, and 6) regulations. The initial approach is to identify applications and protect IP; then consult with market-specific clients to develop ~~SAT~~SA technology for their specific application and demonstrate improved product performance. Later strategy will shift development costs to the client.

PROGRESS: The Company has developed proprietary Signal Advance technology which operates on broadband analog signals (over a specified frequency range) with little signal distortion. Prototype SA circuits have been developed for various application-specific signals and a number of SA circuit designs have been tested using a range of analog test signals. The company is located near the Texas Medical Center in Houston and has broad contacts in a number of its research institutions.

~~SAI~~The ~~has~~Company ~~initiated~~is pursuing collaborations with private entities and research institutions to ~~protect~~implement ~~its~~SA ~~intellectual~~circuitry ~~property, further develop/refine SAT, embody~~ in microelectronics (integrated circuitry), ~~and~~develop/refine ~~test~~SA technology for ~~improved performance in~~ biomedical applications byand ~~the~~demonstrate ~~use~~improved ofperformance ~~SAT.~~resulting ~~Although~~from the ~~collaborations~~use ~~terms~~of ~~are~~SA ~~not~~technology. ~~yet~~The ~~established, the~~ company expects to assume the costs to develop/refine ~~SAT~~SA technology and its microelectronic implementation, ~~as well as~~ intellectual property protection and pilot studies to confirm improvements resulting from the implementation of the Company’s proprietary technology. ~~Collaborations~~ Projects related to the use of SA technology in specific biomedical applications are likely to be funded through research grants or take the form of joint ventures.

InThe ~~the~~Company ~~year-ended~~initiated ~~December~~a ~~31,~~joint ~~2014~~venture relationship operating under Biodyne Development, LLC to which the Company ~~has~~is ~~initiated~~providing ~~the~~consulting ~~investigation~~services ofand ahas ~~specific~~licensed ~~biotechnology~~intellectual ~~application~~property ~~for~~in ~~its~~exchange ~~proprietary~~for ~~technology,~~equity ~~specifically,~~in ~~neural~~the ~~training systems~~venture.

~~VALIDATION/RECOGNITION:~~The Company’s corporate offices were flooded during Hurricane Harvey at the end of August 2017. The Company incurred significant losses in terms of the office assets (the office structure, furniture, computers, etc), however, all intellectual property, experimental results, prototypes, and the majority of business information were secured. We have been slowly recovering from these losses and are moving forward to achieve our business goals.

~~Scientific~~VALIDATION/RECOGNITION: Prototype SA circuit design was tested using a range of simulated test signals as well as bioelectric (cardiac) signals. The results were reviewed and confirmed by University facility (including Ph.D. physicists and engineers). This study resulted in completion of a successful doctoral study, by the Company's President, Dr. Hymel, at the University of Texas Health Science Center at Houston in the Texas Medical Center (2010);

~~Technical~~Scientific: A ~~peer-reviewed~~Prototype ~~feature~~SA ~~article~~circuit ~~summarizing~~design ~~the~~was ~~technology,~~tested ~~study~~using a range of simulated test signals as well as bioelectric (cardiac) signals. The results, were reviewed and ~~broad~~confirmed ~~range~~by ofUniversity ~~potential~~facility ~~SAT~~(including ~~applications~~Ph.D. ~~was~~physicists ~~published~~and engineers). This study resulted in completion of a successful doctoral study, by the ~~IEEE~~Company’s ~~Circuits~~President, ~~and~~Dr. ~~Systems~~Hymel, ~~Magazine~~at the University of Texas Health Science Center at Houston in ~~2011~~the Texas Medical Center (2010);

6Technical: A peer-reviewed feature article summarizing the technology, study results, and a broad range of potential SA technology applications was published in the IEEE Circuits and Systems Magazine in 2011;

Commercial: ~~SAI~~ SA was awarded first place in the 2011 Goradia Innovation Prize competition. The selection was based on: 1) the commercial potential of the technology, 2) the soundness of the business plan, 2) the potential for job growth within the region, and 4) the likelihood of significant long-term success.;

Innovation: ~~The~~ ~~Intellectual~~For ~~Property~~the ~~Section~~intellectual ofproperty ~~the~~underlying ~~Oklahoma~~Signal ~~Bar~~Advance ~~Association~~technology, ~~named~~ Dr. Chris M. Hymel, the Company'’s ~~president,~~Founder and President was named the 2012 Innovator of the Year, ~~for~~by ~~his~~the ~~development~~Intellectual ~~work~~Property onSection ~~Signal~~of ~~Advance~~the ~~technology~~Oklahoma Bar Association. In addition, the State Bar of Texas, Intellectual Property Section, named Dr. Hymel, the 2015 Inventor of the Year.

~~REVENUE~~6 ~~GENERATION:~~Table The Company plans to continue to refine and develop SAT, demonstrate improved performance in targeted applications, pursue related intellectual property protection and begin to commercialize the technology through licensure. SA technology is in the development and early commercialization stage. To date, the Company has not yet sold any products or licensed the technology, is not yet profitable, currently lacks sufficient capital to generate revenue or operate the business in a profitable manner and has not generated sufficient revenues to fund planned R&D, marketing and intellectual protection in the near-term. SAI continues to rely upon capital investment to cover the projected costs of ~~executing the Company's business plan and effectively commercialize its proprietary Signal Advance technology.~~Contents

~~BROAD~~REVENUE ~~RISKS AFFECTING THE COMPANY~~GENERATION: The Company isplans ~~subject~~to continue to ~~numerous~~refine ~~risks~~and develop SA technology, ~~which~~demonstrate ~~are~~improved ~~more~~performance ~~fully~~in ~~discussed~~targeted applications, pursue related intellectual property protection and begin to commercialize the technology through licensure. SA technology is in the ~~section~~development ofand ~~this~~early ~~prospectus~~commercialization ~~entitled~~stage. ~~'Risk~~To ~~Factors'~~date, the Company has not yet sold any products or licensed the technology, is not yet profitable, currently lacks sufficient capital to generate revenue or operate the business in a profitable manner and has not generated sufficient revenues to fund planned R&D, marketing and intellectual protection in the near-term. ~~Some~~ ofSA continues to rely upon capital investment to cover the ~~more~~projected ~~significant~~costs ~~risks~~of ~~included~~executing the ~~following:~~Company’s business plan and effectively commercialize its proprietary Signal Advance technology.

·BROAD RISKS AFFECTING THE COMPANY: The Company is ~~undercapitalized~~subject ~~and~~to ~~has~~numerous ~~limited~~risks, ~~liquidity~~which are more fully discussed in the section of this prospectus entitled ‘Risk Factors’. Some of the more significant risks included the following:

· Current and prospective investors that they will be unable to review certain financial and other disclosures that would have been contained in missing periodic reports, which would have provided an additional source of information for their evaluation of their investment in the company. · the company is no longer eligible to register securities on Form S-3 and will be unable to use short-form registration until it has timely filed all required reports under the Exchange Act for the 12 months before filing a registration statement. This could increase its transaction costs and adversely impact its ability to raise capital in a timely manner. · The Company is undercapitalized and has limited liquidity. · The Company is in the development/early commercialization stage. · The technology is novel and thus requires recognition and acceptance in various markets. · If the Company does not successfully license its technology, it may never achieve profitability. · As a result of the industry competition, the Company may not gain enough market share to be profitable. · If the Company fails to protect its proprietary technology, its competitive position may be impaired. · There will be a limited trading market for the Company’s common stock · The market price of our common stock may fluctuate significantly and may decline.

·EMERGING GROWTH COMPANY STATUS: The ~~technology~~Company qualifies as an ‘emerging growth company’ as defined in Section 2(a)(19) of the Securities Act of 1933 and, as such, is ~~novel~~allowed to provide in this report more limited disclosures than an issuer that would not so qualify. Furthermore, for as long as we remain an emerging growth company, we will qualify for certain limited exceptions from investor protection laws such as the Sarbanes-Oxley Act of 2002 and ~~thus~~the ~~requires~~Investor ~~recognition~~Protection and ~~acceptance~~Securities inReform ~~various~~Act ~~markets~~of 2010. Unlike other public companies, SA is not required to:

· Ifprovide an auditor’s attestation report on management’s assessment of the effectiveness of our system of internal control over financial reporting pursuant to Section 404(b) of the Sarbanes-Oxley Act of 2002; · comply with any new requirements adopted by the Public Company ~~does~~Accounting ~~not~~Oversight ~~successfully~~Board ~~license~~(PCAOB), ~~its~~requiring ~~technology~~mandatory audit firm rotation or a supplement to the auditor’s report in which the auditor would be required to provide additional information about the audit and the financial statements of the issuer; · comply with any new audit rules adopted by the PCAOB after April 5, it2012, ~~may~~unless ~~never~~the ~~achieve~~Securities ~~profitability~~and Exchange Commission determines otherwise; · provide certain disclosure regarding executive compensation required of larger public companies; or · obtain shareholder approval of any golden parachute payments not previously approved.

·7 AsTable ~~a result~~ of ~~the industry competition, the Company may not gain enough market share to be profitable.~~Contents

·We Ifwill ~~the~~cease ~~Company fails~~ to ~~protect~~be ~~its~~an ~~proprietary~~‘emerging ~~technology,~~growth ~~its~~company’ ~~competitive~~upon ~~position~~the ~~may~~earliest ~~be impaired.~~of:

· ~~There~~When ~~will~~we behave a$1.0 ~~limited~~billion ~~trading~~or more in annual revenues; · When we have at least $700 million in market ~~for~~value ~~the~~of ~~Company's~~our common ~~stock~~units held by non-affiliates; · When we issue more than $1.0 billion of non-convertible debt over a three-year period; or · The last day of the fiscal year following the fifth anniversary of our initial public offering.

·In ~~The~~addition, ~~market~~Section ~~price~~107 of ~~our~~the ~~common~~JOBS ~~stock~~Act ~~may~~also ~~fluctuate~~provides ~~significantly~~that an emerging growth company can take advantage of the extended transition period provided in Section 7(a)(2)(B) of the Securities Act for complying with new or revised accounting standards. In other words, an emerging growth company can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. We are electing to take advantage of the extended transition period, and ~~may~~as ~~decline~~a result, we will not be required to comply with new or revised accounting standards on the relevant dates on which adoption of such standards is required for non-emerging growth companies.

~~EMERGING~~CORPORATE ~~GROWTH COMPANY STATUS~~INFORMATION: ~~The~~Our ~~Company~~principal ~~qualifies~~executive asoffices anare ~~'emerging~~located ~~growth~~at ~~company'~~2520 asCounty ~~defined~~Road ~~in Section 2(a)(19) of the Securities Act of 1933 and~~81, ~~as such~~Rosharon, isTexas ~~allowed to provide in this report more limited disclosures than an issuer that would not so qualify~~77583. ~~Furthermore,~~Our ~~for~~website as long as we remain an emerging growth company, we will qualify for certain limited exceptions from investor protection laws such as the Sarbanes-Oxley Act of 2002 and the Investor Protection and Securities Reform Act of 2010. Unlike other public companies, SAI is ~~not required to:~~www.signaladvance.com.

·AVAILABLE ~~provide~~INFORMATION: anWe ~~auditor's~~will ~~attestation~~provide, ~~report~~upon onrequest ~~management's~~and ~~assessment~~free of ~~the~~charge, ~~effectiveness~~paper copies of our ~~system~~Annual ofReport ~~internal~~on ~~control~~Form ~~over~~10-K, ~~financial~~Quarterly ~~reporting~~Reports ~~pursuant~~on Form 10-Q and Current Reports on Form 8-K, including any amendments to ~~Section~~the ~~404~~foregoing reports, as soon as is reasonably practicable after such material is electronically filed with, or furnished to, the Securities and Exchange Commission (bthe “SEC”). A copy of ~~the~~this ~~Sarbanes~~Annual Report on Form 10-~~Oxley~~K ~~Act~~is located at the SEC’s Public Reference Room at 100 F Street, NE, Washington, D.C. 20549. Information on the operation of ~~2002;~~the Public Reference Room can be obtained by calling the SEC at 1-800-SEC-0330. The public may also download these materials from the SEC’s website at http://www.sec.gov.

·Item ~~comply~~1A. ~~with~~Risk any new requirements adopted by the Public Company Accounting Oversight Board (PCAOB), requiring mandatory audit firm rotation or a supplement to the auditor's report in which the auditor would be required to provide additional information about the audit and the financial statements of the issuer;Factors

·Not ~~comply~~applicable ~~with~~to ~~any~~smaller ~~new~~reporting ~~audit rules adopted by the PCAOB after April 5, 2012, unless the Securities and Exchange Commission determines otherwise;~~companies.

·Item ~~provide~~2. ~~certain~~Description ~~disclosure regarding executive compensation required~~ of ~~larger public companies; or~~Property

·We ~~obtain~~do ~~shareholder~~not ~~approval~~own of any ~~golden~~real ~~parachute~~estate ~~payments~~or ~~not~~other ~~previously approved~~properties.

7Item 3. Legal Proceedings

We ~~will~~know ~~cease~~of no legal proceedings to bewhich anwe ~~'emerging~~are ~~growth~~a ~~company'~~party ~~upon~~or ~~the~~to ~~earliest~~which any of: our property is the subject which are pending, threatened or contemplated or any unsatisfied judgments against us.

·Item ~~When~~4. weSubmission ~~have~~of ~~$1.0~~Matters ~~billion~~to ora ~~more~~Vote inof ~~annual~~Security ~~revenues;~~Holders

~~· When we have at least $700 million in market value of our common units held by non-affiliates;~~None.

·8 ~~When~~Table ~~we issue more than $1.0 billion~~ of ~~non-convertible debt over a three-year period; or~~Contents

·PART ~~The last day of the fiscal year following the fifth anniversary of our initial public offering.~~II

~~CORPORATE~~MARKET INFORMATION: ~~Our~~ ~~principal~~On ~~executive~~April ~~offices~~15, ~~are~~2016, ~~located~~the Company filed a Form 15 with the Securities and Exchange Commission (“SEC”) to voluntarily suspend its SEC reporting obligations. The Company was eligible to suspend the SEC reporting obligations by filing a Form 15 under Section 12(h) of the Act as it currently has fewer than 300 shareholders of record. The Company anticipates the registration of its common stock may be terminated 90 days after such filing per SEC regulations at ~~2520~~which ~~County~~time, ~~Road~~the 81Company’s securities will no longer trade on the OTC Bulletin Board, ~~Rosharon~~however, ~~Texas~~they ~~77583. Our~~may ~~website~~remain iseligible ~~www~~for quotation on the Pink Sheets.~~signaladvance.com.~~

~~Item~~The 1ACompany’s Board of Directors considered a number of factors in making this decision, including the low liquidity of the stock, the ongoing costs of continuing fulfillment of the reporting obligations and the demands on management to comply with the reporting requirements. ~~Risk~~ ~~Factors~~The Company believes that the time and expense of complying with the reporting obligations outweighs the benefits received by the Company by continuing to fulfill these obligations. Management plans to focus its time and resources on further development and commercialization of its proprietary technology in order to drive business performance and shareholder value. The Company has the right to withdraw the Form 15 and continue SEC reporting at which time all delinquent reports must be filed within sixty (60) days of such notice.

~~Not~~Trading ~~applicable~~in stocks quoted on the pink Sheets is often thin and is characterized by wide fluctuations in trading prices due to ~~smaller~~many ~~reporting~~factors that may be unrelated to a company’s operations or business prospects. We cannot assure you that there will be a market in the future for our common stock. Pink Sheet securities are not listed or traded on the floor of an organized national or regional stock exchange. Instead, Pink Sheet securities transactions are conducted through a telephone and computer network connecting dealers in stocks. Pink Sheet issuers are traditionally smaller companies that do not meet the financial and other listing requirements of a regional or national stock exchange.

~~Item~~NUMBER ~~2. Description~~OF HOLDERS: As of ~~Property~~December 31, 2016, the 12,407,342 issued and outstanding shares of common stock were held by a total of 180 shareholders of record.

~~CORPORATE INFORMATION~~DIVIDENDS: ~~Our~~ ~~principal~~No ~~executive~~cash ~~offices~~dividends ~~are~~were ~~located~~paid aton ~~2520~~our ~~County~~shares ~~Road~~of 81common stock during the fiscal years ended December 31, ~~Rosharon~~2016, ~~Texas~~2015 ~~77583~~and 2014. ~~Our~~ ~~website~~We ishave ~~www~~not paid any cash dividends since our inception and do not foresee declaring any cash dividends on our common stock in the foreseeable future.~~signaladvance.com.~~

~~Item~~RECENT ~~3. Legal~~SALES ~~Proceedings~~OF UNREGISTERED SECURITIES:

WeDuring ~~know of no legal proceedings to which we are a party or to which any of our property is~~ the ~~subject~~year ~~which~~ended ~~are~~December ~~pending~~31, ~~threatened~~2014, orthe ~~contemplated~~Company ormade ~~any~~the ~~unsatisfied~~following ~~judgments~~Common ~~against~~Stock ~~us.~~issuances:

~~Item~~1) 4121,667 shares of common stock to various individuals for cash proceeds of $156,500; 2) 145,000 shares of the Company’s common stock valued at $145,000 to repay $145,000 of the related party line of credit. ~~Submission~~ 3) 461,334 shares of ~~Matters~~common stock valued at $627,001 to afive ~~Vote~~consultants in exchange for services. 4) 25,000 shares of ~~Security~~common ~~Holders~~stock valued at $25,000 to members of the Board of Directors in exchange for services.

~~None.~~During the year ended December 31, 2015, the Company made the following Common Stock issuances:

81) 97,317 shares of common stock valued at $75,488 to consultants in exchange for services. 2) 59,000 shares of common stock valued at $33,750 to Officers and Members of the Board of Directors in exchange for services. 3) 222,850 shares of common stock valued at $139,638 to partially repay the line of credit - shareholder balance. 4) 2,500 shares of common stock to an individual for cash proceeds of $1,875.

~~PART~~9 IITable of Contents

~~Item~~During 5.the ~~Market~~year ~~for~~ended ~~Common~~December ~~Equity~~31, ~~and~~2016, ~~Related~~the ~~Stockholder~~Company ~~Matters~~ made the following Common Stock issuances:

~~MARKET~~1) ~~INFORMATION: There~~329,000 isshares aof ~~limited public market for our~~ common ~~shares. Our~~stock ~~common~~valued ~~shares~~at ~~are~~$32,900 ~~quoted~~to onconsultants ~~the~~in ~~OTC~~exchange ~~Bulletin~~for ~~Board at this time~~services. ~~Trading~~ in2) ~~stocks~~1,215,000 ~~quoted~~shares onof ~~the~~common ~~OTC~~stock ~~Bulletin~~valued ~~Board~~at is$111,500 ~~often~~to ~~thin~~partially ~~and~~repay isthe ~~characterized~~line byof ~~wide~~credit-shareholder ~~fluctuations~~balance. in3) ~~trading~~33,265 ~~prices~~shares ~~due~~of tocommon ~~many~~stock ~~factors~~valued ~~that~~at ~~may~~$3,327 ~~be unrelated~~ to a ~~company's~~short-term ~~operations~~loan orfrom ~~business~~a ~~prospects~~Director/shareholder. We ~~cannot~~4) ~~assure~~175,000 ~~you~~shares ~~that~~of ~~there~~Common ~~will~~stock bewere asold ~~market in the future~~ for ~~our~~$17,500 ~~common stock~~cash.

~~OTC~~Subsequent ~~Bulletin~~to ~~Board~~December ~~securities~~31, ~~are~~2016, ~~not listed or traded on~~ the ~~floor~~Company ofmade an organized national or regional stock exchange. Instead, OTC Bulletin Board securities transactions are conducted through a telephone and computer network connecting dealers in stocks. OTC Bulletin Board issuers are traditionally smaller companies that do not meet the ~~financial~~following ~~and other listing requirements of a regional or national~~ stock ~~exchange.~~issuances:

~~NUMBER~~During OFthe ~~HOLDERS: As~~year ofended December 31, ~~2014~~2017, the ~~10,273,410~~Company ~~issued~~made ~~and~~the ~~outstanding~~following ~~shares~~Common ofStock ~~common stock were held by a total of 173 shareholders of record.~~issuances:

~~DIVIDENDS: No~~1) ~~cash~~275,000 ~~dividends~~shares ~~were~~of ~~paid~~common onstock ~~our~~valued at $27,500 to consultants in exchange for services. 2) 80,000 shares of common stock ~~during~~valued ~~the~~at ~~fiscal~~$8,000 ~~years~~to ~~ended~~Officers ~~December~~and ~~31,~~members ~~2014~~of ~~and~~the ~~2013~~Board of Directors in exchange for services. We ~~have~~3) ~~not~~770,000 ~~paid~~shares ~~any~~of ~~cash~~common ~~dividends~~stock ~~since~~valued ~~our~~at ~~inception~~$77,000 ~~and~~to dopartially ~~not~~repay ~~foresee~~the ~~declaring~~line ~~any~~of ~~cash~~credit-shareholder ~~dividends~~balance. on4) ~~our~~753,000 ~~common~~shares of Common stock inwere ~~the~~sold ~~foreseeable~~for ~~future~~$75,300 cash.

~~RECENT~~From ~~SALES~~January OF1, ~~UNREGISTERED~~2018 ~~SECURITIES~~through the date of this report, the Company made the following stock issuances:

~~During~~1) 2,000,000 shares of common stock valued at $100,000 to partially repay the ~~year~~line ~~ended~~of ~~December~~credit-shareholder 31balance. 2) 100,000 ~~2013~~shares of common stock valued at $8,000 ~~the~~to ~~Company~~Officers ~~made~~and members of the ~~following~~Board ~~Common~~of ~~Stock~~Directors ~~issuances:~~in exchange for services. 3) 50,000 shares of common stock valued at $2,500 to consultants in exchange for services

1)These ~~1,000,000~~issuances of unregistered shares were ~~issued~~exempt pursuant to Section 4(2) of the ~~Company's~~Securities ~~President~~Act as these were privately negotiated transactions in which there was ~~issued~~no 1advertising and no commissions paid. Accordingly,~~000,000~~ ~~per~~the stock certificates representing these shares were issued with restrictive legends indicating that the ~~terms~~shares ofhave IPnot ~~assignment~~been ~~agreement~~registered ~~valued~~and atmay ~~$1,000,000~~not be traded until registered or otherwise exempt from registration.

2)PURCHASE ~~116,750~~OF ~~shares~~OUR ~~were~~EQUITY ~~issued~~SECURITIES inBY ~~exchange~~OFFICERS ~~for~~AND ~~services~~DIRECTORS: ~~rendered valued at $116,750~~None.

~~During~~OTHER ~~the~~STOCKHOLDER ~~year ended December 31, 2014, the Company made the following Common Stock issuances~~MATTERS: None.

1)Item ~~121,667~~6. ~~shares~~Selected ofFinancial ~~common stock to various individuals for cash proceeds of $156,500;~~Data

2)Not ~~145,000~~applicable ~~shares of the Company's common stock valued at $145,000~~ to ~~repay~~smaller ~~$145,000~~reporting ~~of the loan payable~~companies.

3)Item ~~461,334~~7. ~~shares~~Management’s ofDiscussion ~~common~~and ~~stock~~Analysis ~~valued~~of atFinancial ~~$627,001~~Condition toand ~~five~~Results ~~consultants~~of ~~in exchange for services.~~Operations

4)The 25following discussion should be read in conjunction with our financial statements,~~000~~ ~~shares~~including ofthe ~~common~~notes ~~stock~~thereto, ~~valued~~appearing atelsewhere ~~$25~~in this annual report. The following discussion contains forward-looking statements that reflect our plans,~~000~~ toestimates ~~members~~and ofbeliefs. Our actual results could differ materially from those discussed in the ~~Board~~forward-looking ofstatements. ~~Directors~~Our audited financial statements are stated in ~~exchange~~United ~~for~~States ~~services~~Dollars and are prepared in accordance with United States Generally Accepted Accounting Principles.

~~Subsequent~~RESULTS toOF ~~year ended December 31, 2014, and prior to the date of this report, the Company made the following Common Stock issuances:~~OPERATIONS

1)The ~~26,667~~Company ~~shares~~has ofincurred ~~common~~recurring ~~stock~~losses ~~valued~~to atdate. ~~$40~~Our financial statements have been prepared assuming that we will continue as a going concern and,~~000~~ accordingly, do not include adjustments relating to ~~two~~the ~~consultants~~recoverability inand ~~exchange~~realization ~~for~~of ~~services~~assets and classification of liabilities that might be necessary should we be unable to continue in operation.

2) 10~~,000~~ ~~shares~~Table of ~~common stock valued at $15,000 to three members of the Board of Directors in exchange for services.~~Contents

~~These~~Our ~~issuances~~auditors ofhave ~~unregistered~~issued ~~shares~~a ~~were~~going ~~exempt~~concern ~~pursuant~~opinion as the Company has generated insufficient revenues to ~~Section~~fund ~~4(2)~~planned ofresearch and development, commercialization and intellectual protection in the ~~Securities~~near-term. ~~Act~~The asCompany ~~these~~will ~~were~~continue ~~privately~~to ~~negotiated~~rely ~~transactions~~on incapital ~~which~~investment ~~there~~to ~~was~~cover nothe ~~advertising~~projected costs to execute its business plan and nocommercialize ~~commissions~~its ~~paid~~proprietary signal advance technology and anticipates the need for additional capital to meet our long term operating requirements. ~~Accordingly~~Additional capital will be raised through, ~~the~~among ~~stock~~other ~~certificates~~things, ~~representing~~the ~~these~~sale ~~shares~~of ~~were~~equity ~~issued~~or ~~with~~debt ~~restrictive~~securities. ~~legends~~There ~~indicating~~is no assurance that the ~~shares~~Company ~~have~~will ~~not~~be ~~been~~able ~~registered~~to ~~and~~raise ~~may~~sufficient ~~not~~capital bewhich ~~traded~~would ~~until~~require ~~registered~~operations orto ~~otherwise~~be ~~exempt~~scaled ~~from~~back ~~registration~~accordingly.

9The majority of the Company’s resources have historically been devoted to technology development and protection of its proprietary technology. During the years ended December 31, 2016, 2015 and 2014, the majority of our resources have been allocated to the development of potential applications for our proprietary technology and raising the capital required to successfully execute our business plan.

~~PURCHASE~~The OFCompany ~~OUR~~continues ~~EQUITY~~to ~~SECURITIES~~pursue BYconsulting ~~OFFICERS~~work ~~AND~~which ~~DIRECTORS: None~~is either directly related to SA technology development or may lead to a potential future collaboration.

~~OTHER~~The ~~STOCKHOLDER~~Company’s ~~MATTERS: None~~Founder and President, Dr. Chris M. Hymel, was recognized as the 2015 Inventor of the Year by the State Bar of Texas, Intellectual Property Section. Selection was based on the intellectual property (patent) underlying Signal Advance technology, potential contribution of the invention to society and impact on Texas economy.

~~Item~~Outside 6.of ~~Selected~~medical ~~Financial~~applications, ~~Data~~ the Company established a relationship with a technology development firm for circuit prototyping and implementation in instrumentation used in the oil and gas industry with the goal of applying Signal Advance technology to improve sensor/instrument performance.

~~Not~~The ~~applicable~~Company has begun development of a Neural Training delivery system, a part of the growing Digital Brain Health market. Neural Training has been shown to ~~smaller~~improve ~~reporting~~brain ~~companies~~function, specifically, cognition and memory. The system relies to the detection and analysis of bioelectric signal from the brain (EEG’s) to assess and adjust the individualized training protocols. The Company plans to implement its proprietary Signal Advance technology to offset the delays associated with the detection and analyses of EEG’s in order to improve training efficiency and efficacy. The Company has engaged technologists experienced in developing electronics for the Neural Training system to potentially improve brain function,. The initial target population is the elderly suffering from mild cognitive impairment. To that end, The Company is collaborating with the Gerontology Dept. at the University of Texas Medical Branch (UTMB) in Galveston, Texas. In addition, the Company is a prospective joint venture for the possibility of using Neural Training as an adjunct to cancer therapy.

~~Item~~Subsequent 7.to ~~Management's~~the ~~Discussion~~periods ~~and~~covered ~~Analysis~~by ofthis ~~Financial~~comprehensive ~~Condition~~10-K report, the Company initiated a joint venture relationship operating under Biodyne Development, LLC to which the Company is providing consulting services and ~~Results~~has oflicensed ~~Operations~~intellectual property in exchange for equity in the venture.

The ~~following~~Company’s ~~discussion~~corporate ~~should~~offices bewere ~~read~~flooded induring ~~conjunction~~Hurricane ~~with~~Harvey ~~our~~at ~~financial~~the ~~statements,~~end ~~including~~of ~~the~~August ~~notes~~2017. ~~thereto,~~The ~~appearing~~Company ~~elsewhere~~incurred insignificant ~~this~~losses ~~annual~~in ~~report.~~terms ~~The~~of ~~following~~the ~~discussion~~office ~~contains~~assets ~~forward-looking~~(the ~~statements~~office ~~that~~structure, ~~reflect~~furniture, ~~our~~computers, ~~plans~~etc), ~~estimates~~however, ~~and~~intellectual ~~beliefs. Our~~property, ~~actual~~experimental results, ~~could~~prototypes, ~~differ~~and ~~materially~~the ~~from~~majority ~~those~~of ~~discussed~~our inbusiness ~~the~~records ~~forward-looking~~were ~~statements. Our~~secured ~~audited~~or ~~financial~~recovered. ~~statements~~We ~~are~~have ~~stated~~been inslowly ~~United~~recovering ~~States~~from ~~Dollars~~these losses and are ~~prepared~~moving inforward ~~accordance~~to ~~with~~achieve ~~United~~our ~~States~~business ~~Generally Accepted Accounting Principles~~goals.

~~RESULTS~~INCOME: OFNo ~~OPERATIONS~~revenues were recognized in the years ended December 31, 2016, 2015 or 2014.

WeEXPENSES: ~~have~~Expenses ~~incurred~~are ~~recurring~~classified ~~losses~~into tothe ~~date.~~following ~~Our~~six ~~financial~~broad ~~statements~~categories: ~~have~~1) ~~been~~General ~~prepared~~and ~~assuming~~Administrative, ~~that~~2) weSales ~~will~~and ~~continue~~Marketing, as3) aIntellectual ~~going~~Property ~~concern~~4) ~~and,~~Professional ~~accordingly~~Services, do ~~not~~5) ~~include~~Research ~~adjustments~~and ~~relating~~Development and 6) Depreciation. The Company has engaged consultants to accomplish its goals over the ~~recoverability~~last ~~and~~few ~~realization~~years. ofGiven ~~assets~~sufficient ~~and~~capital, ~~classification~~the majority of ~~liabilities~~these ~~that~~consultants ~~might~~have beexpressed ~~necessary~~interest ~~should~~in weworking befull-time ~~unable~~for tothe ~~continue~~Company. inProfessional ~~operation~~Services includes expenses for such services as legal, accounting/auditing, transfer agent, investor and public relations, video/graphics, securities/reporting, engineering and director’s fees.

~~Our~~11 ~~auditors~~Table have issued a going concern opinion as the Company has generated insufficient revenues to fund planned R&D, marketing and intellectual protection in the near-term. SAI will continue to rely on capital investment to cover the projected costs to execute the Company's business plan and commercialize its proprietary signal advance technology. We expect we will require additional capital to meet our long term operating requirements. We expect to raise additional capital through, among other things, the sale of ~~equity or debt securities. There is no assurance that the Company will be able to raise sufficient capital which would require operations to be scaled back accordingly.~~Contents

~~The~~Expenses ~~majority~~decreased ofrelated ~~the~~to ~~Company's~~professional ~~resources~~services ~~have~~in ~~historically~~years ~~been~~ended ~~devoted~~December to31, ~~technology~~2016 ~~development~~and 2015. The decreased costs are associated with 1) accounting, audits and ~~protection~~reporting ofin ~~its~~fulfillment ~~proprietary~~of ~~technology.~~reporting ~~During~~requirements with the ~~year~~Securities ~~ended~~and ~~December~~Exchange 31Commission, ~~2014,~~2) ~~significant~~public ~~resources~~and ~~have~~investor ~~been~~relations ~~allocated~~and, to3) ~~initiating~~sales/marketing efforts related general commercialization of ~~our~~the Company’s proprietary technology. ~~and~~The ~~raising~~Company ~~the~~continues ~~capital~~to ~~required~~seek capital to ~~successfully~~fund ~~execute~~on-going ~~our~~efforts ~~business~~related ~~plan.~~to ~~The~~in ~~Company~~scientific, ~~will~~technical ~~continue~~and tocommercial ~~pursue~~validation, ~~consulting~~business ~~work~~development ~~which~~and ishas ~~either~~focused ~~directly~~its ~~related~~resources toon SAdevelopment ~~technology~~of ~~development~~specific orapplications ~~may~~for ~~lead~~our toproprietary atechnology, ~~potential~~specifically, ~~future~~on ~~collaboration~~the Neural Training system product.

~~INCOME: In~~The Company continues to incur expenses related to the on-going prosecution of our patent application in Europe and maintenance of our patents in the U.S., China and Mexico. In fiscal year ended ~~2013~~December 31, ~~the~~2016 ~~Company~~resources ~~recognized~~continued ~~revenue~~to inbe applied to intellectual property protection the ~~amount~~majority of $2which was applied to prosecution (preparation and submission of amendments and additional disclosures and renewal fees,~~350~~ etc.) Noof ~~revenues~~the ~~were~~European ~~recognized~~patent application resulted in the ~~year~~patent ~~ended~~grant ~~December~~by 31the European Patent Office in January, 2017. Patents have previously been issued in China (November 2012), the U.S. (May 2013) and Mexico (April 2014). In addition, the Indian Patent application is currently under examination and the Company has responded to the first office action from the Indian patent office.

All costs associated with intellectual property (IP) protection have been expensed. IP expenses totaled $10,242, $7,190 and $8,911, in year ended December 31, 2016, 2015 and 2014, respectively. The increase in IP related expenses reflects the increased activity related to the examinations of the European and Indian patent applications. Further discussion regarding the intellectual property can be found in Note B – Intellectual Property, of the Financial Statements.

~~EXPENSES: Expenses~~The ~~are~~reduced classified into the following six broad categories: 1) General and Administrative, 2) Sales and marketing, 3) Intellectual Property 4) Professional Services, 5) Research and Development and 6) Depreciation, SAI has engaged consultants to accomplish its goals over the last two years. Given sufficient capital, the majority of these consultants have expressed interest in working full-time for the Company. Professional Services includes expenses for ~~such~~professional services asallowed ~~legal,~~the ~~accounting/auditing,~~Company ~~transfer~~to ~~agent,~~apply ~~investor~~additional ~~and~~resources ~~public~~to ~~relations,~~research ~~video/graphics, securities/reporting, engineering~~ and ~~director's~~development ~~fees.~~reflected ~~Expense increases seen~~ in ~~year~~increased ~~ended~~focus ~~December~~on ~~31,~~a ~~2014,~~biomedical ~~relative~~application tofor ~~the~~SA ~~preceding fiscal year reflect increased costs associated with 1) accounting~~technology, ~~audits and reporting in fulfillment of reporting requirements with the Securities and Exchange Commission~~specifically, 2)a ~~public~~Neural ~~and~~Training ~~investor~~delivery ~~relations,~~system 3)as ~~seeking~~well ~~capital~~as ~~to fund~~ on-going ~~efforts related to in~~ scientific, technical and commercial validation, business development and investigation into specific applications for our proprietary technology and 4) initiation of a sales/marketing efforts to commercialize the Company's proprietary technology, specifically, the engagement VEDI Partners to pursue license agreements. On the other hand, in the year-ended December 31, 2013, $1,000,000 in equity was paid to the Company's President per the terms of the IP assignment. Further, we incurred expenses related to ~~the on-going prosecution of our patent~~ applications in the ~~U.S.,~~oil ~~Europe~~ and ~~Mexico,~~gas ~~three of which have since issued. Increased research~~ and ~~development~~transportation ~~expenses reflect the Company's investigation regarding a specific biomedical application for SA technology as well as on-going efforts related to in scientific, technical and commercial validation~~markets.

InExpenses for fiscal ~~year~~years ended December 31, ~~2014 and 2013~~2016, ~~significant~~2015 ~~resources were applied to the acquisition~~ and ~~protection~~2014 ofwere ~~our~~as ~~intellectual property. In 2013, a large installment was due per the terms of the assignment agreement. In addition, intellectual property protection involved~~follows: 1) responses to preliminary searches and initial office actions resulting from the international filings, 3) preparation and submission of amendments and additional disclosures in the US Patent and Trademark Office (USPTO) as well as the European and Mexican Patent Offices, 4) reviews of, and responses to, office actions by the US, European and Mexican patent offices and 5) issuance and annual renewal fees. Patents have been issued in China (Nov. 2012), the U.S. (May 2013) and Mexico (Apr. 2014).

All costs associated with intellectual property (IP) protection have been expensed. IP acquisition and protection costs totaled $8,911, in year ended December 31, 2014, and $1,039,508 the year ended December 31, 2013. Further discussion regarding the intellectual property can be found in Note B – Intellectual Property, of the Financial Statements).

	2016		2015		2014
General and Administrative	$	25,375	$	35,168	$	27,987
Sales/Marketing		-		600		450,000
Depreciation		1,406		1,570		1,851
Intellectual Property		10,242		7,190		8,911
Professional Services		61,535		154,260		292,118
Research and Development		81,655		81,300		34,000

~~Expenses~~COMPREHENSIVE ~~for~~LOSS: ~~fiscal~~In ~~years~~additional, ~~ended~~the ~~December~~Company 31included a realized gain on “Long-term Investment” of $24,930 ~~2014~~in ~~and~~the ~~2013~~year ~~were~~ended asDecember ~~follows:~~31, 2015.

	2014	2013
General and Administrative	27,987	44,275
Sales and Marketing	450,000	-
Intellectual Property	8,911	1,039,508
Professional Services	292,118	93,509
Research and Development	34,000	28,000
Depreciation	1,851	2,717

The net loss for the years-ended December 31, 2016, 2015 and 2014 were $180,213, $301,526 and $814,867, respectively.

~~Comprehensive~~LIQUIDITY ~~loss: Includes~~AND anCAPITAL ~~unrealized loss on "Available for Sales Securities" of $13 in the year ended December 31, 2014.~~RESOURCES

11CURRENT ASSETS: As of December 31, 2016, the Company had cash and cash equivalents of $114. These assets are used as working capital to execute the Company’s business plan. As such, the Company requires additional capital through debt or equity financing to fund operations over the next 12 months.

~~LIQUIDITY~~12 ~~AND~~Table ~~CAPITAL~~of ~~RESOURCES~~Contents

~~CURRENT~~FIXED ASSETS: As ofFixed ~~December~~assets 31(office/laboratory equipment, ~~2014~~computers, ~~the~~etc.) ~~Company~~were ~~had~~$2,777, ~~cash~~$3,953 and ~~cash equivalents of~~ $374,~~177.~~730, ~~These assets are used~~ as ~~working~~of ~~capital~~December to31, ~~execute~~2016, ~~the~~2015 ~~Company's~~and ~~business plan. As such~~2014, ~~the Company requires additional capital through debt or equity financing to fund operations over the next 12 months~~respectively.

~~Fixed~~Change ~~assets~~in ~~(office/laboratory~~fair ~~equipment)~~value ~~were~~for ~~$4,730~~a ~~and~~“Long-term Investment” was a realized loss of $324,~~913,~~930 asin ofthe year ended December 31, ~~2014 and 2013, respectively~~2015.

~~Change~~LIABILITIES: inLiabilities ~~fair~~include ~~value~~a ~~for~~Line anof ~~Available~~Credit ~~for~~provided ~~Sale~~by ~~Security~~the isCompany’s anPresident ~~unrealized~~which ~~loss~~totaled of$12,380, $134,704 inand ~~the~~$10,769 ~~year~~as ~~ended~~of December 31, 2016, 2015 and 2014, respectively. In the year ended 2016, $111,500 of the debt was converted to equity issued to the Company’s President.

~~LIABILITIES~~SHAREHOLDERS’ EQUITY: ~~Liabilities~~ ~~include~~The aaccumulated ~~Line~~deficit ~~of Credit provided by the Company's President which~~ totaled $105,~~769~~559,498, $5,379,285 and $~~122~~5,~~906~~052,829 asfor ofyears ended December 31, ~~2014~~2016, 2015 and ~~2013~~2014, respectively. InThe ~~the~~shares ~~year~~issued ~~ended~~and ~~2014,~~outstanding ~~$145,000~~as of ~~the~~years ~~debt~~ended ~~was~~December ~~converted~~31, to2016, ~~equity~~2015 ~~issued~~and to2014, ~~the~~totaled ~~Company's~~12,407,342, ~~President~~10,655,077 and 10,273,410, respectively.

~~SHAREHOLDERS'~~OFF-BALANCE ~~EQUITY~~SHEET TRANSACTIONS: ~~The~~ ~~accumulated~~There ~~deficit~~are ~~totaled~~no ~~$5,052,829~~off-balance ~~and~~sheet $4items,~~237,962~~ ~~for~~all ~~years~~transactions ~~ended~~are ~~December~~in ~~31,~~U.S. ~~2014 and 2013~~dollars, ~~respectively. The shares issued~~ and ~~outstanding~~the asCompany ofis ~~years~~not ~~ended~~currently ~~December~~subject ~~31,~~to ~~2014~~currency ~~and~~fluctuations ~~2013,~~or ~~totaled~~similar ~~10,273,410~~market ~~and 9,520,409, respectively~~risks.

~~OFF-BALANCE~~PLAN ~~SHEET~~OF ~~TRANSACTIONS: There~~OPERATION ~~are~~AND ~~no off-balance sheet items, all transactions are in U.S. dollars, and SAI is not currently subject to currency fluctuations or similar market risks.~~FUNDING

~~SIGNIFICANT~~We ~~ACCOUNTING~~anticipate ~~POLICIES~~that required working capital will continue to be funded through a combination of our existing funds and further issuances of securities. Working capital requirements will likely to increase in line with the business growth. Existing working capital, further advances, debt instruments, and firm commitments are expected to be adequate to fund our operations over the next three months. We have no lines of credit or other bank financing arrangements. Generally, we have financed operations to date through the proceeds of the private placement of equity and debt instruments.

~~CASH~~In ~~AND~~connection ~~CASH~~with ~~EQUIVALENTS~~our business plan, management anticipates additional increases in operating expenses and capital expenditures relating to: ~~The~~ ~~Company~~i) ~~considers~~technology ~~all~~development, ~~highly~~ii) ~~liquid~~marketing ~~investments~~and ~~purchased~~commercialization, ~~with~~and aniii) ~~original~~intellectual ~~maturity~~property protection. We intend to finance these expenses with further issuances of ~~three~~securities, ~~months~~and ordebt ~~less~~issuances. Thereafter, we expect we will need to beraise ~~cash~~additional ~~equivalents~~capital and generate revenues to meet long-term operating requirements.

~~AVAILABLE~~Additional ~~FOR~~issuances ~~SALE~~of ~~SECURITIES:~~equity ~~The~~or ~~Company~~convertible ~~holds~~debt ~~certain~~securities ~~investments~~will ~~that~~result ~~are~~in ~~treated~~dilution asto ~~available-for-sale~~our ~~securities~~current ~~(FASB~~shareholders. ~~ASC~~Further, ~~320-10-25)~~such ~~and~~securities ~~stated~~might athave ~~their~~rights, ~~fair~~preferences ~~market~~or ~~values.~~privileges ~~All~~senior ~~investments~~to ~~are~~our ~~available~~common ~~for~~stock. ~~current~~Additional ~~operations~~financing ~~and~~may ~~are~~not ~~classified~~be asavailable ~~other~~upon ~~assets~~acceptable interms, ~~the~~or ~~balance~~at ~~sheet~~all. ~~Unrealized~~If ~~holding~~adequate ~~gains~~funds ~~and~~are ~~losses~~not available or are ~~included~~not asavailable aon ~~component~~acceptable ofterms, ~~other~~we ~~comprehensive~~may ~~income~~not ~~(loss)~~be ~~until~~able ~~realized~~to ~~(FASB~~take ~~ASC~~advantage ~~320-35-1).~~of ~~Realized~~prospective ~~gains~~new ~~and~~business ~~losses~~endeavors ~~are~~or ~~included~~opportunities, inwhich ~~'Other~~could ~~Income~~significantly ~~(Loss)'~~and inmaterially ~~the~~restrict ~~income~~our ~~statement~~business operations.

~~RESEARCH~~MATERIAL ~~AND DEVELOPMENT~~COMMITMENTS: ~~Research~~ ~~and~~The ~~development~~Company ~~expenses~~currently ~~are~~leases ~~expensed~~office asspace, ~~incurred~~from ~~until~~its ~~technological~~president, ~~feasibility~~on ~~can~~a bemonth ~~determined. Upfront and milestone payments made~~ to ~~third~~month ~~parties~~basis inat ~~connection~~a ~~with~~rate ~~research~~of ~~and~~$700 ~~development~~per ~~collaborations~~month. ~~are~~Rental ~~expensed~~expense asamounted ~~incurred up~~ to ~~the point of regulatory approval~~$8,400 ~~marketability,~~for ~~licensing, lease, or sale when~~ the ~~net~~years ~~present~~ended ~~value~~December ~~and useful life is able to be determined. Costs associated with intellectual property protection have been expensed until such time as the useful can be determined~~31, ~~at which time~~2016, ~~amounts~~2015 ~~capitalized~~and ~~will be included in intangible property, less the net of accumulated amortization~~2014.

~~REVENUE~~PURCHASE ~~RECOGNITION: Revenue~~OF isSIGNIFICANT ~~not~~EQUIPMENT: beContingent ~~recognized~~on ~~until~~available itfunding iswe ~~realized~~anticipate orpurchasing ~~realizable~~$10,000 ~~and~~on ~~earned.~~equipment Anduring ~~extended discussion regarding~~ the ~~sources~~next oftwelve ~~revenue expected as well as how revenue from these sources will be recognized can be found under the section entitled 'Revenue Recognition' of the Financial Statements~~months.

12GOING CONCERN: The independent auditors’ report accompanying our Financial Statements contain an explanatory paragraph expressing substantial doubt about our ability to continue as a going concern. The financial statements have been prepared “assuming that we will continue as a going concern,” which contemplates that we will realize our assets and satisfy our liabilities and commitments in the ordinary course of business.

~~PROPERTY~~Item ~~AND EQUIPMENT: Fixed Assets (land, buildings and equipment) are carried at cost less accumulated depreciation~~7A. ~~Depreciation~~Quantitative ~~is based on the estimated service lives of depreciable assets~~ and isQualitative ~~depreciated~~Disclosures ~~using~~about ~~the~~Market ~~straight line method. In the case of disposals, assets and related depreciation are removed from the accounts, and the net amounts, less proceeds from disposal, are included in income.~~Risk

~~INCOME~~Not ~~TAXES: The~~applicable ~~Company takes an asset and liability approach~~ to ~~financial~~smaller ~~accounting and~~ reporting ~~for income taxes~~companies. The difference between the financial statement and tax basis of assets and liabilities is determined annually. Deferred income tax assets and liabilities are computed for those differences that have future tax consequences using the currently enacted tax laws and rates that apply to the periods in which they are expected to affect taxable income. Valuation allowances are established, if necessary, to reduce the deferred tax asset to the amount that will assure full realization, As of December 31, 2014, the Company recorded a valuation allowance that reduced its deferred tax assets to zero.

~~CONCENTRATIONS~~13 OFTable ~~CREDIT RISK: Significant concentrations~~ of credit risk consist primarily of investment securities. Investment securities are exposed to various risks, such as interest rate, market and credit risks. Due to the level of risk associated with certain investment securities, it is reasonably possible that changes in the values of investment securities can occur in the near term and that each change could materially affect the amounts reported in the financial statement.Contents

~~IMPAIRMENT: The~~Item ~~Company amortizes intangible assets over their estimated useful lives unless such lives are deemed indefinite~~8. ~~Amortized~~Financial ~~intangible~~Statements ~~assets are tested for impairment based on undiscounted cash flows,~~ and, ifSupplementary impaired, written down to fair value based on either discounted cash flows or appraised values. Intangible assets with indefinite lives are tested annually for impairment and written down to fair value as required.Data

~~NET~~SIGNAL ~~EARNINGS~~ADVANCE, ~~PER SHARE: Basic earnings per share is computed by dividing net income available to common shareholders by the weighted average number of common shares outstanding for the period~~INC.

~~PLAN~~FINANCIAL OFSTATEMENTS ~~OPERATION~~ AND ~~FUNDING~~SUPPLEMENTARY INFORMATION

WeYears ~~anticipate~~Ended ~~that~~December required working capital will continue to be funded through a combination of our existing funds and further issuances of securities. Working capital requirements will likely to increase in line with the business growth. Existing working capital31, ~~further advances~~2016, ~~debt~~2015 ~~instruments,~~ and firm commitments are expected to be adequate to fund our operations over the next three months. We have no lines of credit or other bank financing arrangements. Generally, we have financed operations to date through the proceeds of the private placement of equity and debt instruments. In connection with our business plan, management anticipates additional increases in operating expenses and capital expenditures relating to: i) technology development, ii) marketing and commercialization, and iii) intellectual property protection. We intend to finance these expenses with further issuances of securities, and debt issuances. Thereafter, we expect we will need to raise additional capital and generate revenues to meet long-term operating requirements.2014

~~Additional~~TABLE ~~issuances~~OF of equity or convertible debt securities will result in dilution to our current shareholders. Further, such securities might have rights, preferences or privileges senior to our common stock. Additional financing may not be available upon acceptable terms, or at all. If adequate funds are not available or are not available on acceptable terms, we may not be able to take advantage of prospective new business endeavors or opportunities, which could significantly and materially restrict our business operations.CONTENTS

FINANCIAL STATEMENTS		Page No.

Report of Independent Auditors’ for Years Ended December 31, 2016 and 2015		F 1
Balance Sheets		F 2
Statements of Operations		F 3
Statements of Cash Flows		F 4
Statements of Changes in Shareholders’ Equity (Deficit)		F 5
Notes to Financial Statements		F 6-11

QUARTERLY FINANCIAL INFORMATION (UNAUDITED)

Balance Sheets as of March 31, 2016 and December 31, 2015		F 12
Statement of Operations - Three Month Periods Ended March 31, 2016 and 2015		F 13
Statements of Cash Flows - Three Month Periods Ended March 31, 2016 and 2015		F 14

Balance Sheets as of June 30, 2016 and December 31, 2015		F 15
Statement of Operations - Three and Six Month Periods Ended June 30, 2016 and 2015		F 16
Statements of Cash Flows - Six Month Periods Ended June 30, 2016 and 2015		F 17

Balance Sheets as of September 30, 2016 and December 31, 2015		F 18
Statement of Operations - Three and Nine Month Periods Ended September 30, 2016 and 2015		F 19
Statements of Cash Flows - Nine Month Periods Ended September 30, 2016 and 2015		F 20
Notes to Quarterly Financial Statements		F 21-24

~~MATERIAL~~14 ~~COMMITMENTS:~~Table of Contents

~~The~~LBB ~~Company~~& ~~indemnified~~ASSOCIATES ~~its transfer agent~~LTD., ~~Nevada~~LLP ~~Agency and Transfer Company against any loss related to the re-issuances of 75,000 shares to replace lost certificates.~~

~~The~~7600 ~~Company currently leases office space, from its president, on a month to month basis at a rate of $700 per month~~W. ~~Rental expense amounted to $8~~Tidwell,~~400~~ ~~for~~Suite ~~the~~501 ~~years ended December 31, 2014 and 2013.~~

~~PURCHASE OF SIGNIFICANT EQUIPMENT: Contingent on available funding we anticipate purchasing $30~~Houston,~~000~~ onTX ~~equipment~~77040 ~~during the next twelve months.~~

~~GOING~~Phone: ~~CONCERN~~(713) 800-4343 Fax: (713) 456-2408

~~The~~REPORT ~~independent~~OF ~~auditors'~~INDEPENDENT ~~report~~REGISTERED ~~accompanying~~PUBLIC ~~our~~ACCOUNTING ~~Financial~~FIRM Statements for the years ended December 31, 2014 and 2013 contains an explanatory paragraph expressing substantial doubt about our ability to continue as a going concern. The financial statements have been prepared "assuming that we will continue as a going concern," which contemplates that we will realize our assets and satisfy our liabilities and commitments in the ordinary course of business.

~~Item~~To ~~7A.~~the ~~Quantitative~~Shareholders and ~~Qualitative~~Board ~~Disclosures~~of ~~about~~Directors ~~Market~~of ~~Risk~~

~~Not~~Signal ~~applicable~~Advance, ~~to smaller reporting companies~~Inc.

14Rosharon, Texas

~~Item~~We 8have audited the accompanying balance sheet of Signal Advance, Inc., ~~Financial~~(the ~~Statements~~“Company”) as of December 31, 2016, 2015, and ~~Supplementary~~2014 ~~Data~~ and the related statements of operations, shareholders’ equity (deficit), and cash flows for the years then ended. These financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on these financial statements based on our audits.

~~SIGNAL~~We ~~ADVANCE~~conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. The Company is not required to have, ~~INC~~nor were we engaged to perform, an audit of its internal control over financial reporting. Our audit includes consideration of internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such opinion. An audit also includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.

~~FINANCIAL~~In ~~STATEMENTS~~our ~~AND~~opinion, ~~SUPPLEMENTARY~~the ~~INFORMATION~~financial statements referred to above present fairly, in all material respects, the financial position of Signal Advance, Inc., as of December 31, 2016, 2015, and 2014 and the results of its operations and its cash flows for the year then ended, in conformity with accounting principles generally accepted in the United States of America.

~~Years~~As ~~Ended~~discussed ~~December~~in 31Note A to the financial statements, ~~2014~~the Company’s absence of significant revenues, recurring losses from operations, and ~~2013~~its need for additional financing in order to fund its projected loss in 2017 raise substantial doubt about its ability to continue as a going concern. The 2016, 2015 and 2014 financial statements do not include any adjustments that might result from the outcome of this uncertainty.

~~TABLE~~/S/ OFLBB ~~CONTENTS~~& ASSOCIATES LTD., LLP

FINANCIAL STATEMENTS	Page No.
Report of Independent Auditors'	F-1
Predecessor Auditors' Report	F-2
Balance Sheets	F-3
Statements of Operations	F-4
Statements of Cash Flows	F-5
Statements of Changes in Shareholders' Equity (Deficit)	F-6
Notes to Financial Statements	F-7 – F-13

LBB & Associates Ltd., LLP

15Houston, Texas

~~LBB~~November ~~& ASSOCIATES LTD.~~1, ~~LLP~~2018

~~10260~~F-1 ~~Westheimer~~Table ~~Road,~~of ~~Suite 310~~Contents

~~Houston~~Signal Advance, ~~TX 77042~~Inc.

~~Phone:~~Balance ~~(713) 800-4343 Fax: (713) 456-2408~~Sheets

~~REPORT~~As OFof ~~INDEPENDENT~~December ~~REGISTERED~~31, ~~PUBLIC~~2016, ~~ACCOUNTING~~2015 ~~FIRM~~and 2014

To the Shareholders and Board of Directors of

	2016			2015			2014
ASSETS
Current Assets
Cash or Cash Equivalent	$	114		$	6,258		$	37,177
Total Current Assets		114			6,258			37,177
Property and Equipment, net		2,777			3,953			4,730
Total Property and Equipment, net		2,777			3,953			4,730
Other Assets
Long-Term Investments		-			-			21,438
Total Other Assets		-			-			21,438
TOTAL ASSETS	$	2,891		$	10,211		$	63,345

LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)
Liabilities
Accounts Payable	$	3,698		$	3,707		$	-
Line of Credit - Shareholder		12,380			4,704			10,769
Total Liabilities		16,078			8,411			10,769
Shareholders’ Equity (Deficit)
Common Stock - $0 par value 100,000,000 shares authorized - shares issued and outstanding 10,273,410 as of December 31, 2014 10,655,077 as of December 31, 2015 12,407,342 as of December 31, 2016
Additional Paid-In Capital		5,546,311			5,381,085			5,130,335
Accumulated other comprehensive loss		-			-			(24,930	)
Accumulated Deficit		(5,559,498	)		(5,379,285	)		(5,052,829	)
Total Shareholders’ Equity (Deficit)		(13,187	)		1,800			52,576
TOTAL LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)	$	2,891		$	10,211		$	63,345

~~Signal~~See ~~Advance,~~Accompanying ~~Inc.~~Notes to the Financial Statements

~~Rosharon,~~F-2 ~~Texas~~Table of Contents

~~We have audited the accompanying balance sheet of~~ Signal Advance, Inc., (the "Company") as of December 31, 2014 and the related statements of operations, shareholders' equity (deficit), and cash flows for the year then ended. These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these financial statements based on our audit.

WeStatements ~~conducted our audit in accordance with the standards~~ of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. Our audit includes consideration of internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Company's internal control over financial reporting. Accordingly, we express no such opinion. An audit also includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audit provides a reasonable basis for our opinion.Operations

InYears ~~our~~Ended ~~opinion, the financial statements referred to above present fairly, in all material respects, the financial position of Signal Advance, Inc., as of~~ December 31, ~~2014~~2016, ~~and~~2015 ~~the results of its operations~~ and ~~its~~2014 ~~cash flows for the year then ended, in conformity with accounting principles generally accepted in the United States of America.~~

As discussed in Note A to the financial statements, the Company's absence of significant revenues, recurring losses from operations, and its need for additional financing in order to fund its projected loss in 2015 raise substantial doubt about its ability to continue as a going concern. The 2014 financial statements do not include any adjustments that might result from the outcome of this uncertainty.

	2016			2015			2014
Revenue	$	-		$	-		$	-
Cost of Revenue		-			-			-
Gross Profit		-			-			-
Expense
General & Administrative	$	25,375		$	31,676		$	27,987
Sales/Marketing		-			600			450,000
Intellectual Property		10,242			7,190			8,911
Professional Services		61,535			154,260			292,118
Research & Development		81,655			81,300			34,000
Depreciation		1,406			1,570			1,851
Total Expense		180,213			276,596			814,867
Loss on Investment		-			24,930			-
Net Loss		(180,213	)		(301,526	)		(814,867	)
Components of Comprehensive (Income)/ Loss:
(Gain)/Loss on long-term Investment		-			(24,930	)		(13	)
Comprehensive Loss	$	(180,213	)	$	(326,456	)	$	(814,880	)
Loss per Share - basic and diluted	$	(0.02	)	$	(0.03	)	$	(0.08	)
Shares Outstanding - basic and diluted		11,333,210			10,510,870			9,934,010

~~/S/~~See ~~LBB~~Accompanying &Notes ~~ASSOCIATES~~to ~~LTD.,~~the ~~LLP~~Financial Statements

~~LBB~~F-3 &Table ~~Associates~~of ~~Ltd., LLP~~Contents

~~Houston~~Signal Advance, ~~Texas~~Inc.

~~March~~Statements ~~24,~~of ~~2015~~Cash Flow

~~F-1~~Years Ended December 31, 2016, 2015 and 2014

	2016			2015			2014
OPERATING ACTIVITIES
Net loss	$	(180,213	)	$	(301,526	)	$	(814,867	)
Adjustments to reconcile Net Income to net cash provided by operations:
Depreciation		1,406			1,570			1,851
Impairment on Long-Term Investment		-			21,438			-
Stock Compensation		32,900			109,237			652,001
Accounts Payable		(9	)		3,707			-
Net cash used by Operating Activities		(145,916	)		(165,574	)		(161,015	)
INVESTING ACTIVITIES
Purchase of property and Equipment		(230	)		(793	)		(2,668	)
Net cash provided by Investing Activities		(230	)		(793	)		(2,668	)
FINANCING ACTIVITIES
Proceeds from Sale of Common Stock		17,500			1,875			156,500
Proceeds from convertible notes payable		3,326			-			-
Line of Credit - Shareholder, net		119,176			133,573			32,863
Net cash provided by Financing Activities		140,002			135,448			189,363
Net cash increase for period		(6,144	)		(30,919	)		25,680
Cash at beginning of period		6,258			37,177			11,497
Cash at end of period	$	114		$	6,258		$	37,177
Supplemental Disclosure
Interest Paid	$	4,175		$	3,758		$	2,221
Non-Cash Transactions
Long-Term Investment		30,000			5,250			0
Conversion of Debt to Common Stock		3,326			139,637			0
Repayment of Line of Credit-Shareholder in Common Stock		111,500			109,238			145,000
Unrealized Loss on Available for Sale Securities		-			-			13

~~NOTICE: This~~See ~~predecessor~~Accompanying ~~audit~~Notes ~~report~~to ~~is a copy of~~ the ~~report~~Financial ~~issued on January 28, 2014.~~Statements

~~The predecessor auditor has not re~~F-~~issued~~4 ~~the~~Table ~~report due to the cessation~~ of ~~operations.~~Contents

~~Bobby~~Signal J.Advance, ~~Hutton~~Inc.

~~Certified~~Statements ~~Public~~of ~~Accountant~~Changes in Shareholders’ Equity (Deficit)

~~4824~~Years ~~Courtside~~Ended ~~Drive~~December 31, 2016, 2015 and 2014

Fort Worth, TX 76133

Common Stock

Additional

Paid-In

Accumulated

Other Comprehensive

Accumulated

Total

Shareholders’

Shares

Amount

Capital

Gain (Loss)

Deficit

Equity

Balance as of Dec. 31, 2014

10,273,410

5,130,335

(24,930

)

(5,052,829

)

52,576

Shares issued for services

156,317

109,237

Shares issued for related party debt

222,850

139,638

Shares Issued for cash

2,500

1,875

Net Other Comprehensive income

24,930

(24,930

)

Net Loss

(301,526

)

(301,526

)

Balance as of Dec. 31, 2015

10,655,077

5,381,085

(5,379,285

)

1,800

Shares issued for cash

175,000

17,500

Shares issued for services

329,000

32,900

Shares issued for related party debt

1,248,265

114,826

Net Loss

(180,213

)

(180,213

)

Balance as of Dec. 31, 2016

12,407,342

5,546,311

(5,559,498

)

13,817,

~~Report~~See ofAccompanying ~~Independent~~Notes ~~Registered~~to ~~Public~~the ~~Accounting~~Financial ~~Firm~~Statements

~~The~~F-5 ~~Board~~Table of ~~Directors~~Contents

Signal Advance, Inc.

~~2520~~Notes CRto 81Financial Statements

~~Rosharon~~Years Ended December 2016, ~~TX 77583~~2015 and 2014

WeNOTE ~~have audited the accompanying balance sheet of Signal Advance, Inc. (~~A ~~Texas~~- ~~Corporation)~~SUMMARY asOF ofSIGNIFICANT ~~December~~ACCOUNTING ~~31,~~POLICIES 2013, 2012 and 2011, and the related statements of income and retained earnings (accumulated deficit), cash flows and changes in stockholders' equity for the years then ended. The financial statements are the responsibility of management. Our responsibility is to express an opinion on these financial statements based on our audit.

WeNATURE ~~conducted~~OF ~~our~~OPERATIONS ~~audit~~AND inORGANIZATION: ~~accordance~~Signal ~~with~~Advance, Inc. (the ~~standards~~Company) ofwas ~~the~~incorporated ~~Public~~in ~~Company~~Texas ~~Accounting~~on ~~Oversight~~June ~~Board~~4, ~~(United~~1992, ~~States).~~is ~~These~~an ~~standards~~engineering ~~require~~product ~~that~~and weprocedure ~~plan~~development and ~~perform~~consulting ~~the~~firm ~~audit~~focused toon ~~obtain~~the ~~reasonable~~development ~~assurance~~of ~~about~~applications ~~whether~~for ~~the~~emerging ~~financial~~technologies. ~~statements~~The ~~are~~Company ~~free~~has ofsignificant ~~material~~experience ~~misstatements.~~in Ancomputer ~~audit~~technology, ~~includes~~distributed ~~examining~~information systems, onand adata ~~test~~acquisition ~~basis~~and analysis systems, ~~evidence~~as ~~supporting~~well ~~the~~as, ~~amounts~~medical ~~and~~education, ~~disclosures~~intellectual inproperty ~~the~~protection ~~financial~~and ~~statements~~medical-legal litigation support. AnThe ~~audit~~Company ~~also~~has ~~includes~~focused ~~assessing~~its resources on the ~~accounting~~improvement ~~principles~~of ~~used~~signal ~~and~~detection ~~significant~~systems ~~estimates~~through ~~made~~the bydevelopment ~~management,~~and asrefinement ~~well~~of asits ~~evaluating~~proprietary ~~the~~“Signal ~~overall~~Advance” ~~financial~~technology ~~statements~~which ~~presentation.~~has Wepotential ~~believe~~application ~~that~~in ~~our~~a ~~audit~~wide ~~provides~~range aof ~~reasonable~~medical ~~basis~~applications, ~~for~~as ~~our~~well ~~opinion~~as applications outside of biomedicine.

InThe ~~our~~costs ~~opinion,~~incurred ~~the~~in ~~financial~~acquiring ~~statements~~intellectual ~~referred~~property toassignments ~~above~~as ~~present~~well ~~fairly,~~as inthe ~~all~~pursuit ~~material~~of ~~respects,~~domestic ~~the~~and ~~financial~~international ~~position~~patent ofand ~~Signal~~trademark ~~Advance,~~protection ~~Inc.~~are expensed (included as “Intellectual Property” under expenses on the Statements of Operations for the years ended December 31, ~~2013~~2016, ~~2012~~2015, and ~~2011~~2014. These costs include expenses to prepare and ~~the~~prosecute ~~results~~patent ofapplications ~~its~~and ~~operations~~protect the IP, include filing and ~~its~~issuance ~~cash~~fees, ~~flows~~fees for ~~the~~consultants, ~~years~~experts, ~~then~~advisors, ~~ended~~patent inattorneys, ~~conformity~~including ~~with~~foreign ~~accounting~~associates, ~~principles~~patent ~~generally~~applications, ~~accepted~~claims inand other amendments, responses to office actions, etc. Any patent infringement case may hinder the ~~United~~Company’s ~~States~~ability to generate revenues.

~~The~~CASH ~~accompanying~~AND ~~financial~~CASH ~~statements~~EQUIVALENTS: ~~have~~The ~~been prepared assuming that the~~ Company ~~will~~considers ~~continue~~all ashighly aliquid ~~going~~investments ~~concern.~~purchased Aswith ~~discussed~~an inoriginal ~~Note~~maturity Aof inthree ~~the~~months ~~financial~~or ~~statements,~~less ~~the Company's operating losses raise substantial doubt about its ability~~ to ~~continue~~be ascash ~~a going concern~~equivalents. ~~The financial statements do not include any adjustments that might result from this uncertainty.~~

~~Very~~INTANGIBLE ~~truly~~ASSETS ~~yours~~OR LONG LIVED ASSETS: The Company anticipates amortizing intangible assets over their estimated useful lives unless such lives are deemed indefinite. Amortized intangible assets are tested for impairment based on undiscounted cash flows, and, if impaired, written down to fair value based on either discounted cash flows or appraised values. Intangible assets with indefinite lives are tested annually for impairment and written down to fair value as required. No impairment of intangible assets has been identified during any of the periods presented.

/USE OF ESTIMATES IN FINANCIAL STATEMENT PREPARATION: The preparation of the financial statements in conformity with accounting principles generally accepted in the United States of America requires the use of estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reporting period. The Company’s/ ~~Bobby~~financial Jstatements include amounts and all adjustments that, in the opinion of management and based on management’s best estimates and judgments, are necessary to make the financial statement not misleading. ~~Hutton~~Actual results could differ from those estimates.

~~Bobby~~AVAILABLE JFOR SALE SECURITIES: The Company holds certain investments that are treated as available-for-sale securities (FASB ASC 320-10-25) and stated at their fair market values. ~~Hutton~~All investments are available for current operations and are classified as other assets in the balance sheet. Unrealized holding gains and losses are included as a component of other comprehensive income (loss) until realized (FASB ASC 320-35-1). Realized gains and losses are included in ‘Other Income (Loss)’ in the income statement.

~~Certified~~F-6 ~~Public~~Table ~~Accountant~~of Contents

~~Fort~~INVESTMENTS ~~Worth~~IN A LIMITED LIABILITY COMPANY: The Company held a minor investment (3%) in a Limited Liability Company (LLC). The equity method of accounting for investments in general partnerships is generally appropriate for accounting by limited partners for their investments in limited partnerships. The Company’s interest is sufficiently minor as a limited partner that the Company has virtually no influence over the operating and financial policies of the LLC. As such, ~~Texas~~accounting for the investment using the cost method is appropriate. Under the cost method, income recognized by the investor is limited to distributions received, except that distributions that exceed the investor’s share of earnings after the date of the investment are applied to reduce the carrying value of the investment (FASB-ASC 970-323-25).

~~January~~Adjustments 28are made for impairment annually based on an impairment analysis per ASC 350-20-65-1 where the Company compares whether the fair value of the investment is less than its carrying amount which would result in impairment. The Company has recognized impairment as the LLC has discontinued operation, ~~2014~~and no commercial activity is anticipated in the foreseeable future. As such, an adjustment for impairment was made during the year ended December 31, 2015 for the entire carrying value of $21,438.

FRESEARCH AND DEVELOPMENT: Research and development costs are expensed as incurred until technological feasibility can be determined (FASB ASC 730-210-25). Upfront and milestone payments made to third parties in connection with research and development collaborations are expensed as incurred up to the point of regulatory approval, marketability, licensing, lease, or sale when the net present value and useful life is able to be determined. Payments made to third parties subsequent to the aforementioned events will be capitalized. Amounts capitalized for such payments will be included in other intangibles, less the net of the accumulated amortization, once their useful lives can be determined.

17REVENUE RECOGNITION: The Company revenues are generated by: 1) Providing consulting services; 2) Licensing intellectual property; and 3) Providing consulting services to licensees to facilitate implementation. Revenue is not recognized until it is realized or realizable and earned. The Company recognizes as revenue the fees charged clients as referenced below when 1) persuasive evidence of an arrangement exists, 2) the fees charged as royalties and/or for services are substantially fixed or determinable during the period in which services are provided or royalties are collected, 3) the Company and its clients understand the specific nature and terms of the agreed upon transactions, and 4) collectability is reasonable assured after services have been rendered, or according to a royalty payment schedule.

~~Signal~~Consulting ~~Advance~~Revenue - For revenues generated by providing engineering, ~~Inc~~scientific and medical/legal consulting services. Services are charged at an hourly rate and clients are charged and revenue is recognized monthly.

~~Balance~~License ~~Sheets~~Revenue - As part of the Company’s business model and as a result of the Company’s on-going investment in research and development, the Company plans to license and sell the rights to certain of its intellectual property (IP) including internally developed patents, trade secrets and technological know-how.

AsCertain transfers of ~~December~~IP 31to third parties may be licensing/royalty-based, ~~2014~~transaction-based, or other forms of transfer. Licensing/royalty-based fees involve transfers in which the company earns the income over time, as a lump-sum payment or the amount of income is not fixed or determinable until the licensee sells future related products (i.e., variable royalty, based upon licensee’s revenue). Accordingly, following delivery and ~~2013~~or legal conveyance of rights to the aforementioned IP to the client, and following inception of the license term, revenue is recognized in a manner consistent with the nature of the transaction and the earnings process.

	2014			2013
ASSETS
Current Assets
Cash or Cash Equivalent	$	37,177		$	11,497
Total Current Assets		37,177			11,497
Property and Equipment, net		4,730			3,913
Total Property and Equipment, net		4,730			3,913
Other Assets
Available for Sale Securities		-			13
Long-Term Investments		21,438			21,438
Total Other Assets		21,438			21,451
TOTAL ASSETS	$	63,345		$	36,861
LIABILITIES & SHAREHOLDERS' EQUITY (DEFICIT)
Liabilities
Line of Credit - Shareholder	$	10,769		$	122,906
Total Liabilities		10,769			122,906
Shareholders' Equity (Deficit)
Common Stock - $0 par value
100,000,000 shares authorized
- shares issued and outstanding
10,273,410 as of December, 31, 2014
9,520,409 as of December, 31, 2013
Additional Paid-In Capital		5,130,335			4,176,834
Accumulated other comprehensive loss		(24,930	)		(24,917	)
Accumulated deficit		(5,052,829	)		(4,237,962	)
Total Equity (Deficit)		52,576			(86,045	)
TOTAL LIABILITIES & SHAREHOLDERS'S EQUITY(DEFICIT)	$	63,345		$	36,861

F-7

Table of Contents

~~See~~Combined ~~Accompanying~~License/Consulting ~~Notes~~Revenue - in certain circumstances the license agreement will also include consulting services to facilitate the ~~Financial~~use ~~Statements~~of the Company’s IP, in which case the arrangement may include multiple deliverables. If the client is dependent on the consulting services of the Company to bring value to the license then the license and consulting services will be considered a single unit of accounting. If, however, the license has value to the client, independent of the consulting services provided by the Company, then each deliverable has value on a standalone basis. As such each delivered item or items shall be considered a separate unit of accounting (FASB ASC 605-25).

FAlternatively, license terms may contain a citation of milestones of achievement by the licensee. Each milestone may be tied to an increase in the minimum royalty. Under these circumstances, the deliverable, or unit of accounting, consideration may be contingent on the substantive achievement of one or more milestones. As such, revenue is recognized in its entirety in the period in which the milestone is achieved (FASB ASC 605-328).

18During the years ended December 31, 2016, 2015 and 2014, the Company recognized no revenue.

~~Signal~~PROPERTY ~~Advance~~AND EQUIPMENT: Fixed Assets (land, ~~Inc~~buildings and equipment) are carried at cost less accumulated depreciation. Depreciation is based on the estimated service lives of depreciable assets and is provided using the straight line method. In the case of disposals, assets and related depreciation are removed from the accounts, and the net amounts, less proceeds from disposal, are included in income.

~~Statements~~INCOME TAXES: The Company takes an asset and liability approach to financial accounting and reporting for income taxes. The difference between the financial statement and tax basis of ~~Operations~~assets and liabilities is determined annually. Deferred income tax assets and liabilities are computed for those differences that have future tax consequences using the currently enacted tax laws and rates that apply to the periods in which they are expected to affect taxable income. Valuation allowances are established, if necessary, to reduce the deferred tax asset to the amount that will assure full realization (FASB ASC 740). As of both December 31, 2016 and 2015, the Company recorded a valuation allowance that reduced its deferred tax assets to zero.

~~Years~~CONCENTRATIONS ~~Ended~~OF ~~December~~CREDIT 31RISK: Financial instruments which potentially subject the Company to significant concentrations of credit risk consist primarily of investment securities. Investment securities are exposed to various risks, ~~2014~~such as interest rate, market and ~~2013~~credit risks. Due to the level of risk associated with certain investment securities, it is reasonably possible that changes in the values of investment securities can occur in the near term and that each change could materially affect the amounts reported in the financial statement.

	2014			2013
Revenue	$	-		$	2,350
Cost of Revenue		-			-
Gross Profit		-			2,350
Expense
General & Administrative		27,987			44,275
Sales/Marketing		450,000			-
Intellectual Property		8,911			1,039,508
Professional Services		292,118			93,509
R&D Expenses		34,000			28,000
Depreciation		1,851			2,717
Total Expense		814,867			1,208,009
Net Loss		(814,867	)		(1,205,659	)
Components of comprehensive income (loss):
Unrealized loss on available for sale securities		(13	)		-
Comprehensive Loss:	$	(814,880	)	$	(1,205,659	)
Loss per Share - basic and diluted	$	(0.08	)	$	(0.13	)
Weighted Average Shares Outstanding - basic and diluted		9,934,010			9,033,704

GOING CONCERN: The Company is currently conducting operations. However, it has not yet generated sufficient operating revenue to fund its development activities to date. As such, the Company has relied on funding by the Company’s President and the sale of its common stock. There is a substantial doubt that the Company will generate sufficient revenues in future years to meet its operating cash requirements. Accordingly, the Company’s ability to continue operations in the short-term depends on its success in obtaining equity or debt financing in an amount sufficient to support its operations. This could raise doubt as to its ability to continue as a going concern. The financial statements do not include any adjustments that might result from this uncertainty.

~~See~~NOTE ~~Accompanying~~B ~~Notes~~- toINTELLECTUAL ~~the~~PROPERTY ~~Financial Statements~~

~~F-4~~Intellectual property protection is being pursued for the specifically identifiable intellectual property (IP) termed Signal Advance technology. The patents are filed in the name of the inventor, Chris M. Hymel, Ph.D., the Company President and assigned by Dr. Hymel (Assignor) to the Company (Assignee) under an Intellectual Property Assignment Agreement.

19F-8 Table of Contents

~~Signal~~The ~~Advance,~~following ~~Inc.~~table lists the patent applications and issued patents and their respective status:

Statements of Cash Flow

Patent Office	Patent or Appl. No.	Status
United States	8452544	Granted May 2013
China	ZL 200880015288.2	Granted Nov. 2012
Europe	EP 2137817	Granted Jan. 2017
Mexico	325278	Granted Apr. 2014
India	3465/KOLNP/2009	Under examination

~~Years~~Additional ~~Ended~~patent ~~December~~submissions 31related to specific applications, ~~2014~~Signal Advance circuit configurations, and ~~2013~~signal processing techniques as well as claims related to the Neural training system technology are under consideration.

	2014			2013
OPERATING ACTIVITIES
Net Loss	$	(814,867	)	$	(1,205,659	)
Adjustments to reconcile Net Income
to net cash provided by operations:
Depreciation		1,851			2,717
Stock Compensation		652,001			1,116,750
Net cash provided by Operating Activities		(161,015	)		(86,192	)
INVESTING ACTIVITIES
Purchase of Property and Equipment		(2,668	)		(2,024	)
Net cash provided by Investing Activities		(2,668	)		(2,024	)
FINANCING ACTIVITIES
Proceeds from Sale of Common Stock		156,500			-
Line of Credit - Shareholder, net		32,863			91,603
Net cash provided by Financing Activities		189,363			91,603
Net cash increase for period		25,680			3,387
Cash at beginning of period		11,497			8,110
Cash at end of period	$	37,177		$	11,497
Supplemental Disclosure
Interest Paid	$	2,221		$	8,901
Non-Cash transactions:
Unrealized Loss on Available for Sale Securities	$	13		$	-
Repayment of line of credit-Shareholder in common stock	$	145,000		$	-

The IP derives from an assignment of the IP in the form of a patent application filed with the United States Patent and Trademark Office as well as any patents which issue as a result of U.S. and related international patent applications.

~~See~~As ~~Accompanying~~ASSIGNEE, ~~Notes~~the toCompany ~~the~~is ~~Financial~~responsible ~~Statements~~for:

~~F-5~~1) funding and executing activities required for any regulatory approval, development, implementation and commercialization; 2) introducing assigned products which incorporate the patent pending or patented technology to the commercial market; 3) make its best efforts to: a) develop and market assigned products and services, and, b) increase and extend the commercialization of assigned products, and 4) commence the advertising and marketing assigned products not later than 24 months following the granting of the patent

20The assignment was privately negotiated between the Company’s President, Dr. Hymel (Assignor) and the remaining members of the board of directors for the Company (Assignee). Consideration to acquire the IP rights, in the form of equity (specifically 1,525,000 shares of SA common stock, to date) was expensed as the assignment is considered a transaction between entities under common control (FASB ASC 805-50-30-5,6). The value of the common stock issued in exchange for the equity was based on the most recent private sales of stock (FASB ASC 505-50-30-6). In addition, royalties are payable to Assignor on net sales and/or license fees as follows: a) <$10M: 6%; b) $10-$25M: 8%, and c)>$25M: 10%. Assignor’s remedy for non-payment is the termination of the assignment.

~~Signal~~NOTE ~~Advance,~~C ~~Inc.~~- AVAILABLE FOR SALE SECURITIES

~~Statements~~Approximate cost and fair value of ~~Changes~~available infor ~~Shareholders'~~sale ~~Equity~~securities (~~Deficit~~acquired January 10, 2011) as of December 31, 2015 and 2014 are as follows:

Years Ended December 31, 2014 and 2013

		Cost Gross		Gain(Loss)			Fair Value
Equity Securities Available for Sale	Dec. 31, 2015	$	25,000	$	(25,000	)		-
Equity Securities Available for Sale	Dec. 31, 2014	$	25,000	$	(25,000	)		-

	Common Stock				Additional		Accumulated Other						Total
					Paid-in		Comprehensive			Accumulated			Shareholders'
	Shares		Amount		Capital		Gain/(Loss)			Deficit			Equity (Deficit)
Balance as of December. 31, 2012		8,403,659	$	-		3,060,084	$	(24,917	)	$	(3,032,303	)	$	2,864
Shares Issued for services		1,116,750		-		1,116,750		-			- -			1,116,750
Net Loss		-		-		-		-			(1,205,659	)		(1,205,659	)
Balance as of December. 31, 2013		9,520,409				4,176,834		(24,917	)		(4,237,962	)		(86,045	)
Shares issued for cash		121,667		-		156,500		-			-			156,500
Shares issued for services		486,334		-		652,001		-			-			652,001
Shares issued for payment of related party line of credit		145,000		-		145,000		-			-			145,000
Net Other Comprehensive Loss		-		-		-		(13	)		-			(13	)
Net Loss											(814,867	)		(814,867	)
Balance as of December 31, 2014		10,273,410	$	-	$	5,130,335	$	(24,930	)	$	(5,052,829	)	$	52,576

F-9

Table of Contents

~~See~~NOTE ~~Accompanying~~D ~~Notes~~- toPROPERTY ~~the~~AND ~~Financial~~EQUIPMENT ~~Statements~~

~~F-6~~Property and equipment as of December 31, 2016, 2015 and 2014 are summarized as follows:

	2016			2015			2014
Cost / Basis	$	129,497		$	129,267		$	128,475
Accumulated depreciation		(126,720	)		(125,314	)		(123,745	)
Total property and equipment, net	$	2,777		$	3,953		$	4,730

~~Signal~~Depreciation ~~Advance~~expense during the years ended December 31, ~~Inc~~2016, 2015 and 2014 were $1,406, $1,570 and $1,851, respectively.

~~Notes~~NOTE toE ~~Financial~~- ~~Statements~~INCOME TAXES

~~Years~~The ~~Ended~~Company ~~December~~follows ~~2014~~ASC 740-10-50 “Accounting for Income Taxes.” Deferred income taxes reflect the net effect of (a) temporary difference between carrying amounts of assets and ~~2013~~liabilities for financial purposes and the amounts used for income tax reporting purposes, and (b) net operating loss carry-forwards. No net provision for refundable Federal income tax has been made in the accompanying statement of loss because no recoverable taxes were paid previously. Similarly, no deferred tax asset attributable to the net operating loss carry-forward has been recognized, as it is not deemed likely to be realized.

~~NOTE~~The Aprovision -for ~~SUMMARY~~refundable OFfederal ~~SIGNIFICANT~~income ~~ACCOUNTING~~tax ~~POLICIES~~consists of the following for the periods ending:

NATURE OF OPERATIONS AND ORGANIZATION: Signal Advance, Inc. (the Company) was incorporated in Texas on June 4, 1992, is an engineering product and procedure development and consulting firm focused on the development of applications for emerging technologies. The Company has significant experience in computer technology, distributed information systems, and data acquisition and analysis systems, as well as, medical education, intellectual property protection and medical-legal litigation support. The Company has focused its resources on the improvement of signal detection systems through the development and refinement of its proprietary "Signal Advance" technology which has potential application in a wide range of medical applications, as well as applications outside of biomedicine.

	December 31, 2016			December 31, 2015			December 31, 2014
Federal income tax benefit attributed to:
Net operating loss		39,420			63,320			277,000
Valuation allowance		(39,420	)		(63,320	)		(277,000	)
Net benefit		-			-			-

The costs incurred in acquiring intellectual property assignments as well as the pursuit of domestic and international patent and trademark protection are expensed (included as "Intellectual Property" under expenses on the Statements of Operations for the years ended December 31, 2014, and 2013. These costs include expenses to prepare and prosecute patent applications and protect the IP, include filing and issuance fees, fees for consultants, experts, advisors, patent attorneys, including foreign associates, patent applications, claims and other amendments, responses to office actions, etc. Any patent infringement case may hinder the Company's ability to generate revenues.

The cumulative tax effect at the rate of 21% of significant items comprising our net deferred tax amount is as follows:	December 31, 2016			December 31, 2015			December 31, 2014
Deferred tax attributed:
Net operating loss carryover		1,167,461			1,129,616			1,726,400
Less: change in valuation allowance		(1,167,461	)		(1,129,616	)		(1,726,400	)
Net deferred tax asset		-			-			-

~~CASH~~At ~~AND~~December ~~CASH~~31, ~~EQUIVALENTS:~~2016, ~~The~~the Company ~~considers~~had ~~all~~an ~~highly~~unused ~~liquid~~net ~~investments~~operating ~~purchased~~loss ~~with~~carry-forward anapproximating ~~original~~$5,560,000 ~~maturity~~that ofis ~~three~~available ~~months~~to oroffset ~~less~~future taxable income; the loss carry-forwards will start to beexpire ~~cash~~in ~~equivalents~~2028.

~~INTANGIBLE~~Note ~~ASSETS~~F OR- ~~LONG~~LINE ~~LIVED~~OF ~~ASSETS:~~CREDIT The Company anticipates amortizing intangible assets over their estimated useful lives unless such lives are deemed indefinite. Amortized intangible assets are tested for impairment based on undiscounted cash flows, and, if impaired, written down to fair value based on either discounted cash flows or appraised values. Intangible assets with indefinite lives are tested annually for impairment and written down to fair value as required. No impairment of intangible assets has been identified during any of the periods presented (FASB ASC 350-~~30).~~ SHAREHOLDER

~~USE~~The OFPresident ~~ESTIMATES~~has INloaned ~~FINANCIAL~~funds ~~STATEMENT~~to ~~PREPARATION: The preparation of~~ the ~~financial~~Company ~~statements~~under ~~in conformity with accounting principles generally accepted in~~ the ~~United~~terms ~~States~~ of ~~America~~a ~~requires~~Line ~~the use~~ of ~~estimates~~Credit ~~and~~Promissory ~~assumptions~~Note ~~that~~negotiated ~~affect the reported amounts of assets and liabilities~~with, ~~the disclosure of contingent assets~~ and ~~liabilities~~approved ~~at the date of the financial statements~~by, ~~and~~ the ~~reported~~Board ~~amounts~~ of ~~revenues and expenses during the reporting period~~Directors. The ~~Company's~~line ~~financial statements include amounts and all adjustments that, in the opinion~~ of ~~management~~credit ~~and~~is ~~based~~due on ~~management's~~demand, ~~best~~unsecured, ~~estimates~~ and ~~judgments,~~bears ~~are~~interest ~~necessary~~at ~~to make the financial statement not misleading~~2.5% ~~Actual~~per ~~results could differ from those estimates~~quarter.

F-7 10 Table of Contents

22During the year ended December 31, 2016, the Company repaid $111,500 of the Line of Credit payable with 1,215,000 shares of the Company’s common stock. As of December 31, 2016, the remaining balance payable was $12,380 including accrued interest of approximately $4,100.

~~AVAILABLE~~Subsequent ~~FOR~~payments ~~SALE~~in ~~SECURITIES:~~common ~~The~~stock ~~Company~~include ~~holds~~770,000 ~~certain~~shares ~~investments~~valued ~~that are treated as available-for-sale securities (FASB ASC 320-10-25) and stated~~ at ~~their~~$77,000 ~~fair market values. All investments are available for current operations and are classified as other assets~~ in the ~~balance~~year ~~sheet.~~ended ~~Unrealized~~December ~~holding~~31, ~~gains~~2017 and ~~losses~~$1,000,000 ~~are~~shares ~~included~~valued asat a$50,000, ~~component~~as of ~~other~~the ~~comprehensive~~date ~~income~~of ~~(loss)~~this ~~until~~report, ~~realized (FASB ASC 320-35-1). Realized gains and losses are included~~ in ~~'Other Income (Loss)' in the income statement~~2018.

~~INVESTMENTS~~Note ING A– ~~LIMITED~~SHORT-TERM ~~LIABILITY~~LOAN COMPANY: The Company holds a minor investment (3%) in a Limited Liability Company (LLC). The equity method of accounting for investments in general partnerships is generally appropriate for accounting by limited partners for their investments in limited partnerships. The Company's interest is sufficiently minor as a limited partner that the Company has virtually no influence over the operating and financial policies of the LLC. As such, accounting for the investment using the cost method is appropriate. Under the cost method, income recognized by the investor is limited to distributions received, except that distributions that exceed the investor's share of earnings after the date of the investment are applied to reduce the carrying value of the investment (FASB-~~ASC~~ ~~970-323-25).~~SHAREHOLDER

~~Adjustments~~The ~~are~~Company ~~made~~took ~~for~~out ~~impairment~~a ~~annually based on an impairment analysis per ASC 350~~short-~~20-65-1~~term ~~where~~in the ~~Company~~amount ~~compares~~of ~~whether~~$2,500 ~~the~~from ~~fair~~one ~~value~~ of ~~the~~its ~~investment~~Directors/shareholders. isThis ~~less~~loan ~~than~~bore ~~its~~an ~~carrying~~interest ~~amount~~of ~~which~~2.5% ~~would~~per ~~result~~quarter. inThe ~~impairment~~loan, ~~per~~including ~~analysis~~accrued nointerest ~~such~~of ~~adjustment~~$126.50, ~~for impairment~~ was ~~made~~paid ~~during~~in ~~the~~full ~~year~~by ~~ended December 31, 2014. The investment at cost was $21,438 during~~ the ~~years~~issuance ~~ended~~of ~~December 31~~26,265 ~~2014~~shares ~~and~~of ~~2013~~Common Stock.

~~RESEARCH~~NOTE ~~AND~~H ~~DEVELOPMENT: Research and development costs are expensed as incurred until technological feasibility can be determined (FASB ASC 730~~-~~10-25).~~ ~~Upfront~~FACILITIES and milestone payments made to third parties in connection with research and development collaborations are expensed as incurred up to the point of regulatory approval, marketability, licensing, lease, or sale when the net present value and useful life is able to be determined. Payments made to third parties subsequent to the aforementioned events will be capitalized. Amounts capitalized for such payments will be included in other intangibles, less the net of the accumulated amortization, once their useful lives can be determined.LEASE

~~REVENUE RECOGNITION:~~ The Company ~~revenues~~currently ~~are~~leases ~~generated~~office ~~by:~~space, 1)from ~~Providing~~its ~~consulting~~president, ~~services;~~on 2)a ~~Licensing~~month ~~intellectual property; and 3) Providing consulting services~~ to ~~licensees~~month tobasis ~~facilitate~~at ~~implementation.~~a ~~Revenue~~rate isof ~~not~~$700 ~~recognized~~per ~~until it is realized or realizable and earned~~month. ~~The~~Rental ~~Company~~expense ~~recognizes~~amounted asto ~~revenue the fees charged clients as referenced below when 1) persuasive evidence of an arrangement exists~~$8,400 ~~2) the fees charged as royalties and/or~~ for ~~services are substantially fixed or determinable during~~ the ~~period~~years inended ~~which~~December ~~services~~31, ~~are provided or royalties are collected~~2016, 3)2015 ~~the Company~~ and its clients understand the specific nature and terms of the agreed upon transactions, and 4) collectability is reasonable assured after services have been rendered, or according to a royalty payment schedule2014.

~~Consulting~~NOTE ~~Revenue~~I -– ~~For revenues generated by providing engineering, scientific and medical/legal consulting services. Services are charged at an hourly rate and clients are charged and revenue is recognized monthly.~~EQUITY

~~License~~In ~~Revenue - As part of~~ the ~~Company's~~year ~~business~~ended ~~model~~December ~~and~~31, ~~as a result of the Company's on-going investment in research and development~~2015, the Company ~~plans~~made ~~to license and sell~~ the ~~rights~~following toCommon ~~certain~~Stock ~~of its intellectual property (IP) including internally developed patents, trade secrets and technological know-how.~~issuances:

~~F-8~~1) 91,317 shares of common stock valued at $75,488 to six consultants in exchange for services. 2) 222,850 shares of common stock valued at $139,638 to partially repay the related party line of credit. 3) 59,000 shares of common stock valued at $33,750 to Directors in exchange for services. 4) 2,500 shares of common stock valued at $1,875 for cash.

23During the year ended December 31, 2016, the Company made the following Common Stock issuances:

~~The~~1) ~~typical~~329,000 ~~license~~shares ~~will~~of ~~call~~common ~~for~~stock avalued ~~non-refundable~~at ~~initiation fee~~$32,900 ~~escalating~~to ~~minimum~~consultants ~~royalties~~in toexchange befor ~~paid~~services. ~~before~~2) a1,215,000 ~~given~~shares ~~product~~of iscommon ~~marketed,~~stock ~~and~~valued ~~continuing~~at ~~royalties~~$111,500 ~~based~~to onpartially ~~gross~~repay ~~sales~~the ~~once~~related ~~marketing~~party ~~has~~line ~~begun~~of credit. ~~The~~3) ~~license~~33,265 ~~will~~shares ~~also~~of ~~include~~common astock ~~set~~valued ~~amount~~at of$3,327 ~~time~~to ~~for~~a ~~consulting.~~short-term ~~Licensees~~loan ~~will~~from ~~also~~a beDirector/shareholder. ~~required~~4) to175,000 ~~participate~~shares inof ~~patent~~Common ~~maintenance~~stock ~~and~~were ~~defense~~sold for $17,500 cash.

~~Certain~~Subsequent ~~transfers of IP~~ to ~~third~~December ~~parties may be licensing/royalty-based~~31, ~~transaction-based~~2016, ~~or other forms of transfer. Licensing/royalty-based fees involve transfers in which~~ the ~~company~~Company ~~earns~~made the income over time, as a lump-sum payment or the amount of income is not fixed or determinable until the licensee sells future related products (i.e., variable royalty, based upon licensee's revenue). Accordingly, following ~~delivery~~stock and or legal conveyance of rights to the aforementioned IP to the client, and following inception of the license term, revenue is recognized in a manner consistent with the nature of the transaction and the earnings process.Issuances:

~~Combined~~During ~~License/Consulting Revenue - in certain circumstances~~ the ~~license~~year ~~agreement~~ended ~~will~~December ~~also~~31, ~~include consulting services to facilitate the use of the Company's IP~~2017, ~~in which case~~ the ~~arrangement may include multiple deliverables. If the client is dependent on the consulting services of the~~ Company tomade ~~bring value to~~ the ~~license~~following ~~then~~Common ~~the~~Stock license and consulting services will be considered a single unit of accounting. If, however, the license has value to the client, independent of the consulting services provided by the Company, then each deliverable has value on a standalone basis. As such each delivered item or items shall be considered a separate unit of accounting (FASB ASC 605-25).issuances:

~~Alternatively~~1) 275,000 ~~license~~shares ~~terms may contain a citation~~ of ~~milestones~~common ofstock ~~achievement~~valued byat ~~the~~$27,500 ~~licensee. Each milestone may be tied~~ to anconsultants ~~increase~~ in ~~the~~exchange ~~minimum~~for ~~royalty~~services. ~~For~~2) ~~example~~80,000 ~~biomedical~~shares ~~milestones~~of ~~may~~common ~~include~~stock ~~completion~~valued ofat ~~animal trials~~$8,000 ~~submission~~to Officers and ~~then~~Directors ~~approval~~in ofexchange ~~510K~~for ~~applications or pre-market approval by the FDA~~services. ~~Each~~3) ~~licensee~~770,000 ~~pursuing~~shares aof ~~biomedical~~common ~~application~~stock ~~will~~valued beat ~~expected~~$77,000 to ~~develop~~partially ~~its~~repay ~~own~~the ~~clinical~~related ~~data~~party toline ~~secure~~of ~~such~~credit. ~~pre-market notification (510k~~4) ~~or approval. Under these circumstances~~753,000 ~~the~~shares ~~deliverable, or unit~~ of ~~accounting,~~Common ~~consideration~~stock ~~may~~were besold ~~contingent~~for ~~on the substantive achievement of one or more milestones. As such~~$75,300 ~~revenue is recognized in its entirety in the period in which the milestone is achieved (FASB ASC 605-28)~~cash.

~~During~~From ~~the~~January ~~year ended December 31~~1, ~~2014,~~2018 ~~the~~through ~~Company recognized no revenue. During~~ the ~~year~~date ~~ended~~of ~~December~~this 31report, ~~2013,~~ the Company ~~recognized~~made ~~$2,350~~the infollowing ~~revenue.~~stock issuances:

~~PROPERTY~~1) ~~AND EQUIPMENT: Fixed Assets (land~~2,000,000 ~~buildings~~shares ~~and~~of ~~equipment)~~common ~~are~~stock ~~carried~~valued at ~~cost~~$100,000 ~~less~~to ~~accumulated~~partially ~~depreciation.~~repay ~~Depreciation~~the isline ~~based~~of oncredit-shareholder ~~the~~balance. ~~estimated~~2) ~~service~~100,000 ~~lives~~shares of ~~depreciable~~common ~~assets~~stock ~~and~~valued isat ~~provided~~$8,000 ~~using~~to ~~the~~Officers ~~straight~~and ~~line~~members ~~method.~~of In the ~~case~~Board of ~~disposals,~~Directors ~~assets~~in ~~and~~exchange ~~related~~for ~~depreciation~~services. ~~are~~3) ~~removed from the accounts~~50,000 ~~and~~shares ~~the~~of ~~net~~common ~~amounts,~~stock ~~less~~valued ~~proceeds~~at ~~from disposal~~$2,500 ~~are~~to ~~included~~consultants in ~~income.~~exchange for services

~~INCOME~~F-11 ~~TAXES: The~~Table ~~Company takes an asset and liability approach to financial accounting and reporting for income taxes. The difference between the financial statement and tax basis~~ of assets and liabilities is determined annually. Deferred income tax assets and liabilities are computed for those differences that have future tax consequences using the currently enacted tax laws and rates that apply to the periods in which they are expected to affect taxable income. Valuation allowances are established, if necessary, to reduce the deferred tax asset to the amount that will assure full realization (FASB ASC 740). As of December 31, 2014, the Company recorded a valuation allowance that reduced its deferred tax assets to zero.Contents

~~F-9~~Signal Advance, Inc.

24Balance Sheet

~~CONCENTRATIONS~~As ~~OF CREDIT RISK: Financial instruments which potentially subject the Company to significant concentrations~~ of ~~credit~~March ~~risk consist primarily of investment securities. Investment securities are exposed to various risks~~31, ~~such~~2016 ~~as interest rate, market~~ and ~~credit~~December ~~risks. Due to the level of risk associated with certain investment securities~~31, ~~it is reasonably possible that changes in the values of investment securities can occur in the near term and that each change could materially affect the amounts reported in the financial statement.~~2015

GOING CONCERN: The Company is currently conducting operations. However, it has not yet generated sufficient operating revenue to fund its development activities to date. As such, the Company has relied on funding by the Company's President and the sale of its common stock. There is a substantial doubt that the Company will generate sufficient revenues in future years to meet its operating cash requirements. Accordingly, the Company's ability to continue operations in the short-term depends on its success in obtaining equity or debt financing in an amount sufficient to support its operations. This could raise doubt as to its ability to continue as a going concern. The financial statements do not include any adjustments that might result from this uncertainty.(Unaudited)

NOTE B - INTELLECTUAL PROPERTY

	March 31, 2016			December 31, 2015
ASSETS
Current Assets
Cash or Cash Equivalent	$	777		$	6,258
Total Current Assets		777			6,258
Property and Equipment, net		3,602			3,953
Total Property and Equipment, net		3,602			3,953

TOTAL ASSETS	$	4,379		$	10,211

LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)
Liabilities	$			$
Accounts Payable		-			3,707
Line of Credit - Shareholder		30,777			4,704
Total Liabilities		30,777			8,411
Shareholders’ deficit
Common Stock - $0 par value 100,000,000 shares authorized - shares issued and outstanding 10,870,077, as of March 31, 2016 10,655,077, as of December 31, 2015
Additional paid-in capital		5,402,584			5,381,085
Accumulated deficit		(5,428,982	)		(5,379,285	)
Total shareholders’ equity (deficit)		(26,398	)		1,800

TOTAL LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)	$	4,379		$	10,211

~~Intellectual~~F-12 ~~property~~Table ~~protection is being pursued for the specifically identifiable intellectual property (IP) termed Signal Advance technology. The patents are filed in the name~~ of the inventor, Chris M. Hymel, Ph.D., the Company President and assigned by Dr. Hymel (Assignor) to the Company (Assignee) under an Intellectual Property Assignment Agreement. The following table lists the patent applications and issued patents and their respective status:Contents

Patent Office	Patent or Appl. No.	Status
United States	8452544	Issued May 2013
China	ZL 200880015288.2	Issued Nov. 2012
Europe	EP 08 75 4879.8	Under examination
Mexico	MX/A/2009/00921	Issued Apr. 2014
India	3465/KOLNP/2009	Not yet examined

Signal Advance, Inc.

~~Additional~~Statements ~~patent~~of ~~submissions related to specific applications, Signal Advance circuit configurations, and signal processing techniques are in preparation.~~Operations

~~The~~Three IPMonths ~~derives~~Ended ~~from~~March an31, ~~assignment~~2016 ~~of the IP in the form of a patent application filed with the United States Patent~~ and ~~Trademark Office as well as any patents which issue as a result of U.S. and related international patent applications.~~2015

~~As ASSIGNEE, the Company is responsible for:~~(Unaudited)

1) funding and executing activities required for any regulatory approval, development, implementation and commercialization;

	March 31, 2016			March 31, 2015
Expenses
General and Administrative	$	2,346		$	8,568
Depreciation		351			368
Intellectual Property		-			2,690
Impairment Expense		-			21,438
Professional Services		29,000			71,417
Research & Development		18,000			12,750
Total Expense		49,697			117,231
Net Income (Loss)	$	(49,697	)	$	(117,231	)

Loss per share - basic and diluted	$	(0.01	)	$	(0.01	)

Weighted Average Shares Outstanding - basic and diluted		10,837,934			10,287,132

2)F-13 ~~introducing~~Table ~~assigned~~of ~~products which incorporate the patent pending or patented technology to the commercial market;~~Contents

~~F-10~~Signal Advance, Inc.

25Statements of Cash Flow

3)Three ~~make~~Months ~~its~~Ended ~~best~~March ~~efforts to: a) develop and market assigned products and services~~31, ~~and,~~2016 ~~b) increase~~ and ~~extend the commercialization of assigned products, and~~2015

4(Unaudited) ~~commence the advertising and marketing assigned products not later than 24 months following the granting of the patent~~

The assignment was privately negotiated between the Company's President, Dr. Hymel (Assignor) and the remaining members of the board of directors for the Company (Assignee). Consideration to acquire the IP rights, in the form of equity (specifically 1,525,000 shares of SAI common stock, to date) was expensed as the assignment is considered a transaction between entities under common control (FASB ASC 805-50-30-5,6). The value of the common stock issued in exchange for the equity was based on the most recent private sales of stock (FASB ASC 505-50-30-6). In addition, royalties are payable to Assignor on net sales and/or license fees as follows: a) <$10M: 6%; b) $10-$25M: 8%, and c)>$25M: 10%. Assignor's remedy for non-payment is the termination of the assignment.

	March 31, 2016			March 31, 2015
OPERATING ACTIVITIES
Net income (loss)	$	(49,697	)	$	(117,231	)
Adjustments to reconcile Net Income to net cash provided by operations:
Depreciation		351			368
Impairment on Long Term Investment		-			21,438
Stock Compensation		20,000			47,500
Accounts payable		(3,707	)		-
Net cash provided by (used in) Operating Activities		(33,053	)		(47,925	)
INVESTING ACTIVITIES
Purchase of property and equipment		-			(303	)
Net cash used in Investing Activities		-			(303	)
FINANCING ACTIVITIES
Proceeds from Sale of Common Stock		1,500			-
Line of Credit - Shareholder, net		23,573			15,176
Proceeds from convertible note payable		2,500			-
Net cash provided by (used in) Financing Activities		27,573			15,176
Net cash increase (decrease) for period		(5,480	)		(33,052	)
Cash at beginning of period		6,258			37,177
Cash at end of period	$	778		$	4,125

Supplemental Disclosure
Interest paid	$	609		$	633

~~NOTE C~~ F-14 ~~AVAILABLE~~Table ~~FOR~~of ~~SALE SECURITIES~~Contents

~~Approximate~~Signal ~~cost and fair value of available for sale securities (acquired January 10~~Advance, ~~2011) as of December 31, 2014 and 2013 are as follows:~~Inc.

		Cost Gross		Gain(Loss)			Fair Value
Equity Securities Available for Sale	December 31, 2014	$	25,000	$	(25,000	)		-
Equity Securities Available for Sale	December 31, 2013	$	25,000	$	(24,987	)	$	13

Balance Sheets

~~NOTE~~As Dof -June ~~PROPERTY~~30, ~~AND~~2016 ~~EQUIPMENT~~and December 31, 2015

~~Property and equipment as of December 31, 2014 and 2013 are summarized as follows:~~(Unaudited)

	2014			2013
	June 30, 2016			December 31, 2015
Cost / Basis		128,475			125,807
ASSETS
Accumulated depreciation		(123,745	)		(121,894	)
Current Assets
Total property and equipment, net		4,730			3,913
Cash or Cash Equivalent	$	6,636		$	6,258
Total Current Assets		6,636			6,258
Property and Equipment, net		3,250			3,953
Total Property and Equipment, net		3,250			3,953
TOTAL ASSETS	$	9,886		$	10,211
LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)
Liabilities
Line of Credit - Shareholder	$	4,307		$	4,704
Accounts Payable		-			3,707
Total Liabilities		4,307			8,411
Shareholders’ deficit
Common Stock - $0 par value 100,000,000 shares authorized - shares issued and outstanding 11,537,077, as of June 30, 2016 10,655,077, as of December 31, 2015		-			-
Additional paid-in capital		5,469,284			5,381,085
Accumulated other comprehensive loss		-			-
Accumulated deficit		(5,463,705	)		(5,379,285	)
Total shareholders’ equity (deficit)		5,579			1,800
TOTAL LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)	$	9,886		$	10,211

~~Depreciation~~F-15 ~~expense~~Table ~~during~~of ~~the years ended December 31, 2014 and 2013 were $1,851 and $2,717, respectively.~~Contents

~~F-11~~Signal Advance, Inc.

26Statements of Operations

~~NOTE~~Three EMonths -Ended ~~INCOME~~June ~~TAXES~~30, 2016 and 2015

~~The~~Six ~~Company~~Months ~~follows~~Ended ~~ASC~~June ~~740-10-50~~30, ~~"Accounting~~2016 ~~for Income Taxes." Deferred income taxes reflect the net effect of (a) temporary difference between carrying amounts of assets~~ and liabilities for financial purposes and the amounts used for income tax reporting purposes, and (b) net operating loss carry-forwards. No net provision for refundable Federal income tax has been made in the accompanying statement of loss because no recoverable taxes were paid previously. Similarly, no deferred tax asset attributable to the net operating loss carry-forward has been recognized, as it is not deemed likely to be realized.2015

~~The provision for refundable federal income tax consists of the following for the periods ending:~~(Unaudited)

	December 31, 2014			December 31, 2013
	Three Months Ended						Six Months Ended
Federal income tax benefit attributed to:
	June 30,						June 30,
Net operating loss		277,000			409,900
	2016			2015			2016			2015
Valuation allowance		(277,000	)		(409,900	)
Ordinary Income/Expense
Net benefit		-			-
Expense
The cumulative tax effect at the expected rate of 34% of significant items comprising our net deferred tax amount is as follows:	December 31, 2014			December 31, 2013
General and Administrative	$	6,836		$	8,804		$	9,182		$	17,372
Deferred tax attributed:
Depreciation		352			371			703			740
Net operating loss carryover		1,726,400			1,449,400
Impairment Expense		-			-			-			21,438
Less: change in valuation allowance		(1,726,400	)		(1,449,400	)
Intellectual Property		-			1,000			-			3,690
Net deferred tax asset		-			-
Professional Services		9,535			59,945			38,535			131,361
Research and Development		18,000			11,500			36,000			24,250
Total Expense	$	34,723		$	81,620		$	84,420		$	198,851
Net Income (Loss)	$	(34,723	)	$	(81,620	)	$	(84,420	)	$	(198,851	)
Loss per share - basic and diluted	$	(0.00	)	$	(0.01	)	$	(0.01	)	$	(0.02	)
Weighted Average Shares Outstanding - basic and diluted		10,880,868			10,349,799			10,859,401			10,318,392

~~At December 31, 2014, the Company had an unused net operating loss carry~~F-~~forward~~16 ~~approximating~~Table ~~$5,077,600~~of ~~that is available to offset future taxable income; the loss carry-forward will start to expire in 2028.~~ Contents

~~Note~~Signal FAdvance, ~~- LINE OF CREDIT - SHAREHOLDER~~Inc.

~~The~~Statements ~~President has loaned funds to the Company under the terms~~ of aCash ~~Line of Credit Promissory Note negotiated with, and approved by, the Board of Directors. The line of credit is due on demand, unsecured, and bears interest at 2.5% per quarter.~~Flow

~~During~~Six ~~the~~Months ~~year~~Ended ~~ended~~June ~~December 31~~30, ~~2014,~~2016 ~~the~~and Company repaid $145,000 of the loan payable with 145,000 shares of the Company's common stock valued at $145,000. As of December 31, 2014, the remaining balance payable was $10,769 including accrued interest of $2,221.2015

~~NOTE G - FACILITIES LEASE~~(Unaudited)

The Company currently leases office space, from its president, on a month to month basis at a rate of $700 per month. Rental expense amounted to $8,400 for the years ended December 31, 2014 and 2013.

	June 30, 2016			June 30, 2015
OPERATING ACTIVITIES
Net Loss	$	(84,420	)	$	(198,851	)
Adjustments to reconcile Net Income to net cash provided by operations:
Depreciation		703			740
Stock compensation		20,000			85,000
Accounts payable		(3,708	)		-
Impairment on long term investment		-			21,438
Net cash provided by Operating Activities		(67,425	)		(91,673	)
INVESTING ACTIVITIES
Purchase of property and equipment		-			(340	)
Net cash provided by Investing Activities		-			(340	)
FINANCING ACTIVITIES
Proceeds from Shareholder Loan		3,264			-
Line of credit - shareholder		81,473			69,645
Line of Credit Payments		(19,434	)		-
Proceeds from sale of common stock		2,500			-
Net cash provided by Financing Activities		67,803			69,645
Net cash increase for period	$	378		$	(22,368	)
Cash at beginning of period		6,258			37,177
Cash at end of period	$	6,636		$	14,809
Non Cash Transactions
Repayment of Line of Credit-Shareholder in Common Stock	$	65,000		$	50,000

F-12 17 Table of Contents

27Signal Advance, Inc.

~~NOTE~~Balance ~~H – EQUITY~~Sheets

~~During~~As ~~the~~of ~~year~~September ~~ended~~30, 2016 and December 31, ~~2013, the Company made the following Common Stock issuances:~~2015

1(Unaudited) ~~1,000,000 shares were issued to the Company's President per the terms of IP assignment agreement valued at $1,000,000.~~

2) 116,750 shares were issued in exchange for services rendered valued at $116,750.

	September 30, 2016			December 31, 2015
ASSETS
Current Assets
Cash or Cash Equivalent	$	7,580		$	6,258
Total Current Assets		7,580			6,258
Property and Equipment, net		2,899			3,953
Total Property and Equipment, net		2,899			3,953

TOTAL ASSETS	$	10,479		$	10,211

LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)
Liabilities
Accounts payable	$	-		$	3,707
Line of Credit - Shareholder		18,704			4,704
Total Liabilities		18,704			8,411
Shareholders’ deficit
Common Stock - $0 par value 100,000,000 shares authorized - shares issued and outstanding 11,907,342, as of September 30, 2016 10,655,077, as of December 31, 2015		-			-
Additional paid-in capital		5,506,311			5,381,085
Accumulated deficit		(5,514,536	)		(5,379,285	)
Total shareholders’ equity (deficit)		(8,225	)		1,800

TOTAL LIABILITIES & SHAREHOLDERS’ EQUITY (DEFICIT)	$	10,479		$	10,211

~~During~~F-18 ~~the~~Table ~~year~~of ~~ended December 31, 2014, the Company made the following Common Stock issuances:~~Contents

1)Signal ~~121~~Advance,~~667~~ ~~shares of common stock to various individuals for cash proceeds of $156,500;~~Inc.

2)Statements ~~145,000 shares~~ of ~~the Company's common stock valued at $145,000 to repay $145,000 of the related party line of credit.~~Operations

3)Three ~~461,334~~Months ~~shares~~Ended ofSeptember ~~common stock valued at $627~~30,~~001~~ to2016 ~~five~~and ~~consultants in exchange for services.~~2015

4)Nine ~~25,000~~Months ~~shares~~Ended ofSeptember ~~common stock valued at $25~~30,~~000~~ to2016 ~~members~~and ~~of the Board of Directors in exchange for services.~~2015

~~Subsequent to year ended December 31, 2014, and prior to the date of this report, the Company made the following Common Stock issuances:~~(Unaudited)

3) 26,667 shares of common stock valued at $40,000 to two consultants in exchange for services.

Three Months Ended

Nine Months Ended

September 30,

2016

2015

2016

2015

Ordinary Income/Expense

Expense

General and Administrative

6,195

8,625

15,377

25,997

Depreciation

351

427

1,054

1,166

Intellectual Property

2,642

3,500

2,642

7,190

Impairment Expense

21,438

Professional Services

15,000

16,243

53,535

147,605

Research and Development

26,643

12,000

62,643

36,250

Total Expense

50,831

40,795

135,251

218,208

Net Income (Loss)

(50,831

)

(40,795

)

(135,251

)

(239,646

)

Loss per share - basic and diluted

(0.00

)

(0.00

)

(0.01

)

(0.02

)

Weighted Average Shares outstanding - basic and diluted

11,696,395

10,380,077

11,140,435

10,339,180

4)F-19 ~~10,000~~Table ~~shares~~ of ~~common stock valued at $15,000 to three members of the Board of Directors in exchange for services.~~Contents

~~F-13~~ Signal Advance, Inc.

28Statements of Cash Flow

~~Item~~Nine 9.Months ~~Changes~~Ended InSeptember ~~and~~30, ~~Disagreements~~2016 ~~with Accountants on Accounting~~ and ~~Financial Disclosure~~2015

~~None.~~(Unaudited)

Item 9A(T). Controls and Procedures

	September 30, 2016			September 30, 2015
OPERATING ACTIVITIES
Net Loss	$	(135,251	)	$	(239,646	)
Adjustments to reconcile Net Income to net cash provided by operations:
Depreciation		1,054			1,166
Stock compensation		32,900			85,000
Impairment loss		-			21,438
Accounts payable		(3,707	)		-
Net cash provided by Operating Activities		(105,004	)		(132,042	)
INVESTING ACTIVITIES
Purchase of property and equipment		-			(719	)
Long-term Investments		-			-
Net cash provided by Investing Activities		-			(719	)
FINANCING ACTIVITIES
Common stock issued for cash		17,500			-
Proceeds from convertible notes payable		3,263			-
Line of credit - shareholder, net		111,202			97,243
Line of credit payments		(25,639	)		-
Net cash provided by Financing Activities		106,326			97,243
Net cash increase for period	$	1,322		$	(35,518	)
Cash at beginning of period	$	6,258		$	37,177
Cash at end of period	$	7,580		$	1,659
Non Cash Transactions
Repayment of Line of Credit-Shareholder in Common Stock	$	74,827		$	50,000

MANAGEMENT'S REPORT ON DISCLOSURE CONTROLS AND PROCEDURES: Management is responsible for establishing and maintaining adequate internal control over financial reporting (as defined in Exchange Act Rule 13aF-~~15(f)).~~20 ~~Internal~~Table ~~control over financial reporting is a process designed to provide reasonable assurance regarding the reliability~~ of financial reporting and the preparation of financial statements for external purposes in accordance with accounting principles generally accepted in the United States of America. Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that compliance with the policies or procedures may deteriorate. Management evaluated the effectiveness of the Company's internal control over financial reporting as of December 31, 2014 using the criteria established in "Internal Control - Integrated Framework" issued by the Committee of Sponsoring Organizations of the Treadway Commission ("COSO").Contents

ASignal ~~material weakness is a deficiency~~Advance, or combination of deficiencies, in internal control over financial reporting, such that there is a reasonable possibility that a material misstatement of the Company's annual or interim financial statements will not be prevented or detected on a timely basisInc. In its assessment of the effectiveness of internal control over financial reporting as of December 31, 2014, based on the above referenced guidelines, the Company determined that there were control deficiencies that constituted material weaknesses, as described below.

1)Notes ~~We do not have an Audit Committee – While not being legally obligated~~ to ~~have~~Quarterly anFinancial ~~audit~~Statements committee, it is the management's view that such a committee, including a financial expert member, is an important entity level control over the Company's financial statement. Currently the Board of Directors acts in the capacity of the Audit Committee, and does not include a member that is considered to be independent of management to provide the necessary oversight over management's activities.(Unaudited)

2)Note We did not maintain appropriate cash controls – As of December 31, 2014, the Company has not maintained sufficient internal controls over financial reporting for the cash process, including failure to segregate cash handling and accounting functions, and did not require dual signature on the Company's bank accounts. Alternatively, the effects of poor cash controls were mitigated by the fact that the Company had limited transactions in their bank accounts.A

3)QUARTERLY WeFINANCIAL did not implement appropriate information technology controls – As at December 31, 2014, the Company retains copies of all financial data and material agreements and periodically make backups of the Company's data; however there is no formal procedure or evidence of normal backup of the Company's data or off-site storage of data in the event of theft, misplacement, or loss due to unmitigated factors.INFORMATION

~~Accordingly,~~Basis ~~the~~of ~~Company~~Presentation ~~concluded~~- ~~that~~The ~~these~~unaudited ~~control~~consolidated ~~deficiencies~~financial ~~resulted~~statements included herein have been prepared in aaccordance ~~reasonable~~with ~~possibility~~generally ~~that~~accepted aaccounting ~~material~~principles ~~misstatement~~for interim financial information. These consolidated financial statements do not include all of the ~~annual~~disclosures orrequired by generally accepted accounting principles it the United States of America for complete financial statements. These unaudited consolidated interim financial statements ~~will~~should ~~not~~he beread ~~prevented~~in orconjunction ~~detected~~with onthe aconsolidated ~~timely~~financial ~~basis~~statements byin our Annual Report on Form 10-K for the ~~company's~~years ~~internal~~ended ~~controls~~December 31, 2016 and 2015. As aIn ~~result~~the opinion of management, the ~~material~~unaudited ~~weaknesses~~interim ~~described~~consolidated ~~above~~financial statements furnished herein include adjustments, ~~management~~all ~~has~~of ~~concluded~~which ~~that~~are of a normal recurring nature necessary for a fair statement of the ~~Company~~results ~~did~~for ~~not~~all ~~maintain~~the ~~effective~~interim ~~internal~~periods ~~control~~presented. ~~over~~Operating ~~financial~~results ~~reporting~~for asthe ofinterim ~~December~~periods ~~31,~~are ~~2014~~not ~~based~~necessarily onindicative ~~criteria~~of ~~established~~the inresults ~~Internal~~that ~~Control—Integrated~~may ~~Framework~~be ~~issued~~expected byfor ~~COSO~~a full fiscal year.

~~CHANGES~~Note INB ~~INTERNAL~~– ~~CONTROL~~GOING OVER FINANCIAL REPORTING: There has been no change in our internal control over financial reporting identified in connection with our evaluation we conducted of the effectiveness of our internal control over financial reporting as of December 31, 2014, that occurred subsequent to the evaluation that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.CONCERN

~~This~~The ~~annual~~Company ~~report~~is ~~does~~currently ~~not~~conducting ~~include~~operations. anHowever, ~~attestation~~it ~~report~~has ofnot ~~the~~yet ~~Company's~~generated ~~registered~~sufficient ~~public~~operating ~~accounting~~revenue ~~firm~~to ~~regarding~~fund ~~internal~~its ~~control~~development ~~over~~activities ~~financial~~to ~~reporting~~date. ~~Management's~~As ~~report~~such, ~~was~~the ~~not~~Company ~~subject~~has torelied ~~attestation~~on funding by the Company'’s ~~registered~~President ~~public~~and ~~accounting~~the ~~firm~~sale ~~pursuant~~of toits ~~rules~~common ofstock. There is a substantial doubt that the ~~SEC~~Company ~~applicable~~will generate sufficient revenues in future years to anmeet ~~Emerging~~its ~~Growth~~operating ~~Company that~~cash ~~permit~~requirements. Accordingly, the Company’s ability to ~~provide~~continue ~~only~~operations ~~management's~~in ~~report~~the short-term depends on its success in ~~this~~obtaining ~~annual~~equity ~~report~~or debt financing in an amount sufficient to support its operations. This could raise doubt as to its ability to continue as a going concern. The financial statements do not include any adjustments that might result from this uncertainty.

29Note C – SIGNIFICANT ACCOUNTING POLICIES

~~PART~~Estimates ~~III~~- The preparation of financial statements in conformity with generally accepted accounting principles requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

~~Item~~Cash ~~10.~~- ~~Directors,~~Cash ~~Executive~~and ~~Officers~~cash equivalents include short-term, ~~Promoters~~highly ~~and~~liquid ~~Control~~investments ~~Persons~~with maturities of ~~the~~less ~~Company~~than three months when acquired.

~~DIRECTORS~~Income ~~AND~~taxes ~~EXECUTIVE~~- ~~OFFICERS:~~ The ~~following~~Company ~~table~~accounts ~~sets~~for ~~forth~~income ~~the~~taxes ~~names,~~under ~~positions~~ASC ~~and~~740 ~~ages~~“Income ofTaxes” ~~the~~which ~~current~~codified ~~SAI~~SFAS ~~Directors~~109, ~~and~~“Accounting ~~Officers.~~for ~~Directors~~Income ~~are~~Taxes” ~~elected~~and ~~during~~FIN ~~the~~48 ~~annual~~“Accounting ~~shareholders' meeting and serve~~ for ~~one~~Uncertainty ~~year~~in ~~and~~Income ~~until~~Taxes ~~their~~– ~~successors~~an ~~are~~Interpretation ~~elected~~of ~~and~~FASB ~~qualify~~Statement No.109.” ~~Officers~~Under ~~are~~the ~~elected~~asset byand ~~our~~liability ~~board~~method of ~~directors~~ASC ~~and~~740, ~~their~~deferred ~~terms~~tax ofassets ~~office~~and liabilities are atrecognized for the ~~discretion~~future oftax ~~our~~consequences ~~board.~~attributable ~~None~~to differences between the financial statements carrying amounts of ~~our~~existing ~~Directors~~assets isand ~~independent~~liabilities ~~per~~and ~~NASDAQ~~their ~~listing~~respective ~~standards~~tax bases.

Director/Officer	Age	Position/Office
Chris Hymel	57	Director, President/Treasurer
Malcolm Skolnick	79	Director, Secretary
Ron Stubbers	52	Director, Vice-President
Richard Seltzer	60	Director

F-21

Table of Contents

~~All~~Deferred ~~directors~~tax ~~hold~~assets ~~office~~and ~~until~~liabilities ~~the~~are ~~next~~measured ~~annual~~using ~~meeting~~enacted oftax ~~the~~rates ~~shareholders~~expected ofto apply to taxable income in the ~~Company~~years ~~and~~in ~~until~~which ~~their~~those ~~successors~~temporary ~~have~~differences ~~been~~are ~~duly~~expected ~~elected~~to ~~and~~be ~~qualified.~~recovered ~~The~~or ~~Company's~~settled. ~~Bylaws~~Under ~~provide~~ASC ~~that~~740, the ~~Board~~effect ofon ~~Directors~~deferred ~~will~~tax ~~consist~~assets and liabilities of noa ~~less~~change ~~than~~in ~~three~~tax ~~members. In~~rates is recognized in income in the ~~year-ended~~period ~~December~~the ~~31,~~enactment ~~2014~~occurs. ~~one~~A ofvaluation ~~our~~allowance ~~directors,~~is ~~Karl~~provided ~~Zercoe,~~for ~~resigned~~certain deferred tax assets if it is more likely than not that the Company will not realize tax assets through future operations.

~~BIOGRAPHIES:~~Fair Value of Financial Instruments - The Company’s financial instruments as defined by FASB ASC 825-10-50 include cash, investments, and accounts payable and notes payable. All instruments are accounted for on a historical cost basis, which, due to the short maturity of these financial instruments, approximates fair value at March 31, June 30, and September 30, 2016.

~~Chris~~FASB M.ASC ~~Hymel,~~820 ~~Ph.D.~~defines ~~(President/Treasurer,~~fair ~~Director): served as a director and its President and Treasurer since its inception. Dr. Hymel previously founded a computer systems/networking consulting and development firm and~~value, ~~later,~~establishes a ~~medical-legal~~framework firm which developed over 60 animations used in litigation support. He also served on the board of a non-profit corporation, Educational Enrichment Center through 2009. Professional experience also includes technology development at the University of Texas, Neurophysiology Research Center, including the development of proprietary neurostimulation, signal generation and data acquisition systems, and control systems engineering for ~~Shell~~measuring ~~Oil~~fair &value ~~Shell Development Companies and Johnson Controls, Inc. Dr. Hymel holds a doctorate~~ in ~~biomedical~~accordance ~~sciences~~with ~~from~~generally ~~the~~accepted ~~University~~accounting ~~of Texas Health Science Center~~principles, ~~Houston as well as bachelors~~ and ~~masters~~expands ~~degrees~~disclosures inabout ~~electrical~~fair ~~engineering~~value ~~from Texas A&M University~~measurements. ~~Dr.~~ASC ~~Hymel~~820 ~~holds~~establishes ~~multiple patents and has authored~~ a ~~number~~three-tier offair ~~scientific~~value /hierarchy ~~technical~~which ~~publications.~~prioritizes ~~Dr. Hymel developed~~ the ~~proprietary~~inputs ~~Signal~~used ~~Advance technology and successfully demonstrated temporally advanced detection of a range of analog (including bioelectric) signals~~ in ~~his~~measuring ~~doctorate~~fair ~~research~~value ~~completed~~as ~~at the University of Texas Health Science Center in August 2010.~~follows:

~~Malcolm~~Level ~~Skolnick (Secretary, Director): Dr~~1. ~~Skolnick~~Observable ~~received~~inputs ~~his~~such ~~Ph.D. in physics from Cornell University and J.D. from the University of Houston Law Center. He retired in 2008 after ten years~~ as aquoted ~~Director,~~prices ~~President/CEO of CytoGenix, Inc., a publicly traded, development stage biotechnology firm~~ in ~~Houston~~active Texas. Prior to joining CytoGenix, Dr. Skolnick, a tenured professor, held academic positions in the Medical School, the Graduate School of Biomedical Sciences and the School of Public Health (SPH) of the University of Texas Health Science Center, Houston (UT Health). In addition to his service as a Department Chair in the Medical School and professorial duties, Dr. Skolnick directed the UT Health Office of Technology Management, overseeing the University's activities in protecting and licensing its technology portfolio.markets;

DrLevel 2. ~~Skolnick headed the UT Health Neurophysiology Research Center and served as principal investigator of several clinical trials in pain management~~Inputs, ~~smoking~~other ~~cessation~~than ~~and reduction of withdrawal symptoms in drug addiction. He also serves as Director and Vice President of~~ the ~~Southwest~~quoted ~~Health~~prices ~~Technology Foundation, Resolution Forum, Inc., Responsible Community Design International, Inc., and Hudson Forest Homeowners' Association. He has served as an expert witness~~ in ~~intellectual~~active ~~property~~markets, ~~product~~that ~~liability,~~are ~~and~~observable ~~accident~~either ~~reconstruction~~directly ~~matters.~~or ~~Dr.~~indirectly; ~~Skolnick is a registered patent attorney, patented inventor~~ and is licensed to practice law in the State of Texas. In addition to his service on various corporate boards, since his retirement from CytoGenix, Inc., he has been active in patent prosecution and licensing for selected clients and has been an invited lecturer at several local universities.

~~Ron~~Level ~~A, Stubbers (Vice-President, Director): Mr~~3. ~~Stubbers~~Unobservable ~~has~~inputs been developing and manufacturing electronic biomedical devices for over 20 years, much of it while VP of Engineering and VP of Operations for Neuroscan, Inc. and its successor Compumedics, USA from 1991-2003, and aDEPtas, Inc. and its successor InGeneron, Inc. from 2004-Present. His experience includes development and production of medical devices ranging from neurostimulation systems to EEG acquisition and analysis systems. He has also worked in ~~the~~which ~~areas~~there ofis ~~product~~little ~~design~~or ~~and~~no ~~manufacturing~~market ~~engineering~~data, ~~quality,~~which ~~regulatory~~requires and technical support for startup companies. Mr. Stubbers has managed corporate ISO/EN/QSR quality management systems requirements and compliance and European CE and FDA 510K Class II as well as other regulatory approvals for world-wide medical device distribution. Mr. Stubbers received his bachelor's degree in electrical engineering from the ~~University~~reporting ofentity ~~Idaho~~to indevelop ~~1985,~~its ~~completed~~own ~~graduate coursework at the University of Texas, Graduate School of Biomedical Sciences and at Rice University, and completed his MBA at the University of Houston (2013)~~assumptions.

~~Richard~~The C.Company ~~Seltzer~~does ~~(Director): Mr.~~not ~~Seltzer~~have ~~received~~any ~~his~~assets ~~J.D.~~or ~~from~~liabilities ~~South~~measured ~~Texas~~at ~~College~~fair ofvalue ~~Law~~on ina ~~1981~~recurring ~~and~~or ~~his~~nonrecurring ~~LL.M.~~basis inat ~~Taxation~~March ~~from the University of Florida in 1982. Mr. Seltzer has been in private practice for more than thirty years representing both established and startup businesses in acquisitions and mergers~~31, ~~financial~~June ~~and~~30 ~~tax issues, contractual matters, shareholder disputes, real estate acquisitions~~ and ~~general~~September ~~business litigation in Texas State Courts. His practice includes arranging viable capital infusions for ongoing businesses~~30, ~~negotiating business and real estate related contracts~~2016. He has handled the licensing of proprietary information for a non-profit organization in Texas. He also continues to successfully represent numerous taxpayer corporations and individuals before the Internal Revenue Service, including both its Appellate and Collection Divisions as well as representing taxpayers for matters filed with the U.S. Tax Court. For more than fifteen years Mr. Seltzer has been a frequent invited speaker covering general business topics at the People's Law School in conjunction with the University of Houston Law School. He is also an approved mediator in the State of Texas having received his certification in 2008.

~~Mr.~~Impairment ~~Seltzer~~of ~~has~~Long-Lived ~~continued~~Assets to- ~~serve~~The asCompany areviews ~~member~~its oflong-lived ~~the~~assets ~~Board~~and ofcertain ~~Directors~~identifiable ofintangibles ~~Bridges~~for toimpairment ~~Life,~~when aevents ~~nonprofit~~or ~~organization~~changes in ~~Houston,~~circumstances ~~since~~indicate ~~2003~~that the carrying amount of the assets may not be recoverable. HeRecoverability ~~was~~of ~~appointed~~assets into ~~2011~~be asheld and used is measured by a ~~member~~comparison of the ~~Board~~carrying ofamounts ~~Directors~~ of ~~STARBASE,~~the ~~Inc.,~~assets ato ~~federally~~future ~~funded~~net ~~educational~~cash ~~program~~flows ~~working~~expected into ~~conjunction~~be ~~with~~generated by the ~~Department~~assets. ofIf ~~Defense~~such ~~and~~assets are considered impaired, the ~~National~~impairment ~~Guard~~to ~~that~~be ~~works~~recognized ~~with~~is ~~upper~~measured ~~elementary~~by ~~school~~the ~~students~~amount ~~particularly~~by ~~interested~~which inthe ~~math,~~carrying ~~science,~~amount ~~engineering~~of ~~and~~the ~~technology~~assets ~~related~~exceed ~~programs.~~the Infair ~~addition,~~value ~~Mr.~~of ~~Seltzer~~the ~~serves~~assets based on ~~the~~estimated ~~Boards~~future ofcash flows.

~~Directors~~Earnings ofPer ~~the~~Share ~~following~~Information ~~Texas~~- ~~corporations:~~FASB ~~Atlas~~ASC ~~Management~~260, ~~Inc.~~“Earnings ~~(appointed~~Per inShare” ~~2000),~~provides ~~Innovative~~for ~~Tooling~~calculation of “basic” and ~~Accessories,~~“diluted” ~~Inc~~earnings per share. ~~(appointed~~Basic inearnings ~~2007~~per share includes no dilution and is computed by dividing net income (loss), ~~Intuitec,~~available ~~Inc~~to common shareholders by the weighted average common shares outstanding for the period. ~~(appointed~~For inpurposes ~~2003),~~of ~~Milsob~~the ~~Properties~~earnings per share calculation, ~~Inc.~~we ~~(appointed~~consider inshares ~~2008)~~to be issued as issued shares as of the date the shares are earned. HeDiluted ~~has~~earnings ~~also~~per ~~served~~share onreflect the ~~Board~~potential dilution of ~~Directors~~securities that could share in the earnings of ~~Delta~~an ~~Shaver~~entity ~~Company,~~similar ~~Inc~~to fully diluted earnings per share. Basic and diluted loss per share were the same, aat ~~Delaware~~the ~~corporation~~reporting ~~since~~dates, ~~2011~~as there were no common stock equivalents outstanding.

30Share Based Expenses

~~AUDIT~~The ~~COMMITTEE: We~~Company doaccounts ~~not~~for ~~have~~stock-based ancompensation ~~audit~~issued ~~committee~~to ~~financial~~non-employees ~~expert,~~and asconsultants in accordance with the ~~cost~~provisions ~~related~~of ASC 505-50 “Equity - Based Payments to ~~retaining~~Non-Employees” awhich ~~financial~~codified ~~expert~~SFAS at123 ~~this~~and ~~time~~the isEmerging ~~prohibitive~~Issues Task Force consensus in Issue No. ~~Further~~96-18 (“EITF 96-18”), ~~our~~“Accounting ~~President~~for ~~has~~Equity ~~the~~Instruments ~~requisite~~that ~~financial~~are ~~experience~~Issued ~~and~~to ~~knowledge,~~Other ~~thus~~Than Employees for Acquiring or in Conjunction with Selling, weGoods ~~believe~~or Services”. Measurement of share-based payment transactions with non-employees shall be based on the ~~services~~fair value of whichever is more reliably measurable: (a) ~~financial~~the ~~expert~~goods ~~are~~or ~~not~~services ~~warranted~~received; or (b) the equity instruments issued. The fair value of the share-based payment transaction should be determined at the earlier of performance commitment date or performance completion date.

~~SIGNIFICANT~~F-22 ~~EMPLOYEES:~~Table ~~We have no employees other than our directors/officers~~ of ~~which only the President/Treasurer devotes full time to company matters. Others devote time as needed. We intend to hire employees on an as needed basis.~~Contents

~~FAMILY~~Recent ~~RELATIONSHIPS~~accounting pronouncements - In August 2014, the FASB issued a new Accounting Standards Update, Presentation of Financial Statements—Going Concern (Subtopic 205-40): ~~There~~Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern (ASU 2014-15). ASU 2014-15 provides guidance on management’s responsibility to evaluate whether there is substantial doubt about an entity’s ability to continue as a going concern within one year of the date the financial statements are noissued, ~~family~~and, ~~relationships~~if ~~among~~such ~~our~~conditions ~~directors~~exist, ~~executive~~to ~~officers~~provide related footnote disclosures. The guidance is effective for annual periods ending after December 15, ~~director~~2016 ~~nominees~~and orinterim ~~significant~~periods ~~employees~~within annual periods beginning after December 15, 2016. Early adoption is permitted. The Company expects to adopt this guidance when effective and is currently evaluating the effect that the updated standard will have on its financial statements and related disclosures.

~~Item~~In 11August 2016, the FASB issued ASU No. ~~Executive~~2016-15, ~~Compensation~~Statement of Cash Flows (Topic 230), which is intended to reduce diversity in practice in how certain transactions are classified in the statement of cash flows. The guidance addresses eight specific cash flow issues for which current GAAP is either unclear or does not include specific guidance. The guidance is effective for annual periods beginning after December 15, 2017 and interim periods within those annual periods. Early adoption is permitted, provided that all of the amendments are adopted in the same period. This ASU must be adopted using a retrospective transition method. The Company plans to adopt this guidance effective March 31, 2018. The Company has not identified any changes to this guidance that upon adoption will have a material effect on its cash flows.

WeNote ~~are~~D ~~providing~~- ~~compensation~~LINE ~~disclosure~~OF ~~that~~CREDIT ~~satisfies~~- the requirements applicable to emerging growth companies, as defined in the JOBS Act. The summary compensation table below shows certain compensation information paid for services rendered in all capacities to us by our principal executive officer and by each other executive officer whose total annual salary and bonus exceeded $100,000 during years ended December 31, 2014 and 2013. Other than as set forth below, no executive officer's total annual compensation exceeded $100,000 during our last fiscal period.SHAREHOLDER

~~SUMMARY~~The ~~COMPENSATION~~President ~~TABLE:~~has loaned funds to the Company under the terms of a Line of Credit Promissory Note negotiated with, and approved by, the Board of Directors. The line of credit is due on demand, unsecured, and bears interest at 2.5% per quarter.

Name & Position	Year or Period	Salary		Bonus		Stock Awards (1)		Options Awards		Non-Equity Incentive Plan Compensation		Non-Qualified Deferred Compensation Earnings		All Other Compensation (2)		Total
C Hymel Pre./Treas	2013	$	27,000		0	$	81,000		0		0		0	$	4,078	$	112,078
C Hymel Pres/Treas	2014	$	103,000		0	$	5,000		0		0		0	$	2,150	$	110,150

As of March 31, June 30 and September 30, 2016, the amount outstanding was $30,777, $4,307 and $18,704.

~~(1)~~NOTE ~~Non~~E -~~cash~~ ~~compensation:~~FACILITIES ~~Equity issued for services rendered~~LEASE

(The Company currently leases office space, from its president, on a month to month basis at a rate of $700 per month. Rental expense amounted to $2),100 ~~Reimbursement~~for each of ~~medical~~the ~~and~~quarters ~~professional~~ended ~~development~~September ~~expenses~~30, 2016.

~~SAI~~NOTE ~~entered~~F ~~into~~– a consulting agreement with Dr. Chris M. Hymel, the Company President, whereby he was compensated at $108,000 per year in 2014 and 2013, plus limited reimbursement of medical and professional development expenses. Dr. Hymel is expected to devote essentially full-time (at least 40 hours/week) on activities related to the Company. The term of the agreement is year-to-year but may be terminated by giving one month's notice. Eligible medical and professional development expenses are either paid or reimbursed in cash and annual compensation for services rendered has been in the form of equity, specifically common stock, for years ended December 31, 2014 and 2013.EQUITY

31During the nine months ended September 30, 2016, the Company made the following Common Stock issuances:

~~In year ending December 31, 2013, Dr Skolnick received $5,000, in the form of equity (common stock) in exchange for services related to intellectual property protection.~~ During the ~~year~~three months ended ~~December~~March 31, ~~2014~~2016, ~~Mr. Seltzer received $10~~200,000 ~~and~~shares ~~Dr.~~of ~~Skolnick,~~common ~~Mr.~~stock ~~Stubbers~~valued ~~and~~at ~~Mr. Zercoe each received~~ $520,000 ~~(for~~to aconsultants ~~total of $15,000)~~ in ~~the form of equity (common stock) in~~ exchange for services. ~~Other~~ ~~than as described above~~15, ~~all other directors and executive officers received well under less than $10,~~000 ~~compensation~~shares ~~in the same periods, also in the form~~ of ~~equity~~Common ~~(common~~ stock) inwere ~~exchange~~sold for ~~their~~$1,500 ~~services~~cash. ~~No executive officers received a bonus or deferred compensation.~~

~~Other~~During ~~Executive~~the ~~Officer~~three ~~Compensation~~months (ended June 30, 2016, issued 657,000 shares of common stock to ~~date):~~repay $65,700 of related party line of credit. 10,000 shares of Common stock were sold for $1,000 cash.

~~Outstanding~~During ~~Equity~~the ~~Awards:~~three ~~None~~months ~~Option~~ended ~~Exercises/Stock~~September ~~Vested~~30, ~~Table:~~2016, ~~None~~issued ~~Pension~~91,265 ~~Benefits~~shares ~~Table:~~of ~~None~~common ~~Non-qualified~~stock ~~Deferred~~to ~~Compensation~~repay ~~Table:~~$9,127 ~~None~~of ~~All~~related ~~Other~~party ~~Compensation~~line ~~Table:~~of ~~None~~credit. ~~Perquisites~~150,000 ~~Table:~~shares ~~None~~of Common stock were sold for $15,000 cash and 129,000 shares of common stock valued at $12,900 for services.

~~There~~Subsequent ~~are~~to noSeptember ~~employment contracts~~30, ~~compensatory plans or arrangements (except as referenced above for the Company President)~~2016, ~~including payments to be received from~~ the Company ~~with~~issued ~~respect~~500,000 toshares ~~any executive officer~~ of ~~the~~common ~~Company~~stock ~~which would in any way result in payments~~ to ~~any~~repay ~~such person because of his or her resignation~~$40,000 ~~retirement or other termination~~ of ~~employment~~related ~~with~~party ~~the~~line ~~Company or its subsidiaries, any change in control~~ of ~~the Company or a change in the person's responsibilities following a change in control of the Company~~credit. Nor are there any agreements or understandings for any director or officer to resign at the request of another person. None of the Company's directors or executive officers is acting on behalf of or will act at the direction of any other person.

~~COMPENSATION~~F-23 ~~PURSUANT~~Table ~~TO PLANS: There is no retirement, pension, profit sharing, or other plan covering any~~ of our officers and directors. The Company has adopted no formal stock option plans for our officers, directors and/or employees. SAI reserves the right to adopt one or more stock options plans in the future. Presently, there is no plan to issue additional equity in the Company or options to acquire the same to our officers, directors or their affiliates or associates except for compensation of Director and Officers as described previously.Contents

~~CORPORATE~~During ~~GOVERNANCE: Currently~~the year ended December 31, 2017, the Company ~~has~~made nothe ~~formal~~following ~~Audit~~Common orStock ~~Compensation Committee.~~issuances:

~~Item~~1) 12275,000 shares of common stock valued at $27,500 to consultants in exchange for services. ~~Security~~2) ~~Ownership~~80,000 shares of ~~Certain~~common ~~Beneficial~~stock ~~Owners~~valued ~~and~~at ~~Management~~$8,000 to Officers and ~~Related~~Directors ~~Stockholder~~in ~~Matters~~exchange for services. 3) 770,000 shares of common stock valued at $77,000 to partially repay the related party line of credit. 4) 753,000 shares of Common stock were sold for $75,300 cash.

~~The~~From ~~Company~~January ~~is authorized to issue 100~~1,~~000,000~~ ~~shares~~2018 ofthrough ~~common~~the ~~stock,~~date ~~with no par value. Holders~~ of ~~common~~this ~~stock are entitled to one vote per share on all matters subject to shareholder vote. The common stock has no cumulative~~report, ~~preemptive or other subscription rights. All of~~ the ~~presently~~Company ~~issued~~made ~~shares of common stock are fully paid and non-assessable. The Board of Directors may declare dividends payable to holders of common stock out of legally available funds. If~~ the ~~Company~~following ~~is liquidated or dissolved, holders of shares of common~~ stock ~~will be entitled to share ratably in any assets of the Company remaining after satisfaction of all of its liabilities. As of December 31, 2014, 10,273,410 shares had been issued to 173 shareholders.~~issuances:

321) 2,000,000 shares of common stock valued at $100,000 to partially repay the line of credit-shareholder balance. 2) 100,000 shares of common stock valued at $8,000 to Officers and members of the Board of Directors in exchange for services. 3) 50,000 shares of common stock valued at $2,500 to consultants in exchange for services

~~The~~F-24 ~~following~~Table ~~table sets forth the number~~ of shares of common stock that are beneficially owned as of December 31, 2014 by (i) each person known by us to be the beneficial owner of more than 5% of the outstanding shares of our common stock, (ii) each of our directors and executive officers, (iii) all officers and directors as a group and, (iv) all officers and directors and each person known by us to be the beneficial owner of more than 5% of the outstanding shares of our common stock as a group. The persons and entities named in the table have sole voting and sole investment power with respect to the shares set forth opposite the stockholder's name, subject to community property laws, where applicable.Contents

Name of Beneficial Owner	Title of Class	Amount/Nature of Beneficial Ownership(1)	Percent of Class (5)
Chris Hymel, Director/Officer(2,4)	Common	4,540,013	44.2%
Ray and Tricia Corkran(3,4)	Common	821,250	8.0%
Malcolm Skolnick, Director/Officer(2,4)	Common	296,834	2.9%
Ron Stubbers, Director/Officer(2,4)	Common	266,250	2.6%
Richard C. Seltzer, Director(2)	Common	118,000	1.2%
Officers/Directors as a group (5 total)	Common	5,297,347	50.8%
Officers/Directors & Shareholders owning > 5% as a group (6 total)	Common	6,111,597	58.8%

Item 9. Changes In and Disagreements with Accountants on Accounting and Financial Disclosure

~~(1) Beneficial ownership is determined in accordance with SEC rules, and includes any shares as to which the stockholder has sole or shared voting power or investment power~~None. ~~Any indication herein, regarding beneficial ownership, is not an admission, on the part of the stockholder, that he, she or it is a direct or indirect beneficial owner of those shares.~~

Item 9A(2T). ~~The~~Controls ~~address~~and ~~for all Directors/Officers: 2520 CR 81, Rosharon, TX 77583~~Procedures

MANAGEMENT’S REPORT ON DISCLOSURE CONTROLS AND PROCEDURES: Management is responsible for establishing and maintaining adequate internal control over financial reporting (3as defined in Exchange Act Rule 13a-15(f)). ~~The~~Internal ~~address~~control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with accounting principles generally accepted in the ~~Corkrans:~~United ~~321~~States ~~Grand~~of ~~Ranch~~America. ~~Lane~~Because of its inherent limitations, ~~Friendswood~~internal control over financial reporting may not prevent or detect misstatements. Also, TXprojections ~~77546~~of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that compliance with the policies or procedures may deteriorate.

~~(4)~~Management ~~Includes~~evaluated ~~shares~~the ~~held~~effectiveness byof ~~spouses~~the Company’s internal control over financial reporting for the years ended December 31, 2016 and ~~minor~~2015, ~~children.~~based on:

1) guidance provided in the SEC Interpretive Release 33-8810 (5Commission Guidance Regarding Management’s Report on Internal Control Over Financial Reporting Under Section 13(a) ~~The~~or ~~percent~~15(d) of ~~class~~the isSecurities ~~based~~Exchange onAct 10of 1934,~~273,410~~ ~~shares~~2) ofthe ~~common~~Final ~~stock~~Rule ~~issued~~Release No. 33-8809 (Amendments to Rules Regarding Management’s Report on Internal Control Over Financial Reporting, and ~~outstanding~~3) asthe criteria established by the Committee of ~~December~~Sponsoring ~~31,~~Organizations ~~2014~~of the Treadway Commission in Internal Control over Financial Reporting – Guidance for Smaller Public Companies.

~~Item~~A ~~13.~~material ~~Certain~~weakness ~~Relationships~~is ~~and~~a ~~Related~~deficiency, ~~Transactions~~or combination of deficiencies, ~~and~~in ~~Director~~internal ~~Independence~~control over financial reporting, such that there is a reasonable possibility that a material misstatement of the Company’s annual or interim financial statements will not be prevented or detected on a timely basis.

~~CERTAIN~~MANAGEMENT’S ~~RELATIONSHIPS~~REPORT ~~AND~~ON ~~RELATED~~INTERNAL ~~TRANSACTIONS~~CONTROL OF FINANCIAL REPORTING: Management is also responsible for establishing and maintaining adequate internal control over financial reporting. In its assessment of the effectiveness of internal control over financial reporting as of December 31, 2016 and 2015, based on the above referenced guidelines, the Company determined that there were control deficiencies that constituted material weaknesses, as listed below.

The Company owes its President, Chris M Hymel, $10,769 as of December 31, 2014, in the form of an unsecured loan (Line of Credit). The note is due on demand and bears 2.5% interest per quarter. The Company currently leases office space, from its President, on a month to month basis at a rate of $700 per month. The Company obtained rights to the intellectual property though an assignment agreement with its President (discussed in greater detail in Note B - Intellectual Property of the Financial Statements.

	1)	We do not have an Audit Committee - While not being legally obligated to have one, management believes that such a committee, including a financial expert member, is an important entity level control over the Company’s financial statement. Currently, the Board of Directors acts as the Audit Committee, and does not include an independent member to provide the necessary oversight over management’s activities.

	2)	We did not maintain appropriate cash controls - Due to accounting resource limitations, as of December 31, 2016 and 2015, the Company has not maintained sufficient internal controls over financial reporting for the cash process based on the inability to segregate cash handling and accounting functions, and the lack of the requirement for dual signatures on the Company’s bank accounts. This weakness is due to our lack of working capital to hire additional staff during the period covered by this report.

~~Other~~15 ~~than~~Table ~~the President's compensation, related transactions, discussed previously, since the company's inception, there has not been, nor is there currently proposed, any transaction or series~~ of ~~similar transactions with related parties to which the Company was or will be a party:~~Contents

1)However, Inthe ~~which~~effects of poor cash controls were mitigated by the ~~amount~~fact ~~involved~~that ~~exceeds~~the ~~$120,000;~~Company ~~and~~had limited transactions in their bank accounts.

23) InWe ~~which~~did ~~any~~not ~~director~~implement appropriate information technology controls - As of December 31, ~~executive~~2016 ~~officer~~and 2015, ~~shareholder~~the ~~who~~Company ~~beneficially~~retained ~~owns~~copies 5%of orall ~~more~~financial data and material agreements and periodically made backups of ~~SAI~~the ~~common~~Company’s ~~stock,~~data; orhowever ~~any~~there ~~member~~is no formal procedure or evidence of ~~their~~normal ~~immediate~~backup ~~family,~~of ~~had~~the Company’s data or ~~will~~off-site ~~have~~storage aof ~~direct~~data in the event of theft, misplacement, or ~~indirect~~loss ~~material~~due ~~interest~~to unmitigated factors.

~~DIRECTOR~~As ~~INDEPENDENCE~~such, ~~The~~the Company ~~has~~concluded ~~not~~that ~~established~~these ~~its~~control ~~own~~deficiencies ~~definition~~resulted ~~for~~in ~~determining~~a ~~whether~~reasonable ~~its~~possibility ~~directors~~that ~~and~~a ~~nominees~~material ~~for~~misstatement ~~directors~~of ~~are~~the ~~'independent'~~annual ~~nor~~or ~~has~~interim itfinancial ~~adopted~~statements ~~any~~may ~~other~~not ~~standard~~be ofprevented ~~independence~~or ~~employed~~detected byon ~~any~~a ~~national~~timely ~~securities~~basis ~~exchange~~by orthe ~~inter-dealer~~company’s ~~quotation~~internal ~~system~~controls. ~~None~~As a result of the material weaknesses described above, management has concluded that the Company's ~~current~~did ~~directors~~not ~~are~~maintain ~~considered~~effective ~~independent~~internal control over financial reporting as ~~determined~~of byDecember ~~the~~31, ~~NASDAQ~~2016 ~~listing~~and ~~standards~~2015.

33The Company intends to hire additional accounting personnel to assist with financial reporting as soon as our finances will allow, however, due to the increasing number and complexity of pronouncements, emerging issues and releases, and reporting requirements and regulations, we expect there will continue to be some risk related to financial disclosures. The process of identifying risk areas and implementing financial disclosure controls and internal controls over financial reporting required under the Sarbanes-Oxley Act continues to be complex and subject to significant judgment and may result in the identification in the future of areas where we may need additional resources. Additionally, due to the complexity and judgment involved in this process, we cannot guarantee that we will not find or have pointed out to us either by internal or external resources, or by our auditors, additional areas needing improvement or resulting in a future assessment that our controls are or have become ineffective as a result of overlooked or newly created significant deficiencies or unmitigated risks.

~~Item~~CHANGES ~~14.~~IN ~~Principal~~INTERNAL ~~Accountant~~CONTROL ~~Fees~~OVER FINANCIAL REPORTING: There has been no change in our internal control over financial reporting identified in connection with our evaluation we conducted of the effectiveness of our internal control over financial reporting as of December 31, 2016 and ~~Services~~ 2015, that occurred subsequent to the evaluation that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.

AsATTESTATION ofREPORT ~~the~~OF ~~date~~INDEPENDENT ofREGISTERED ~~this~~PUBLIC ACCOUNTING FIRM: This annual report, does not include an attestation report of the Company’s ~~has~~registered ~~incurred approximately~~public ~~$13,350~~accounting infirm ~~fees~~regarding tointernal ~~our~~control ~~principal~~over ~~independent~~financial ~~accountants~~reporting. ~~for~~Management’s ~~professional~~report ~~services~~was ~~rendered~~not insubject ~~connection~~to ~~with~~attestation by the ~~reviews~~Company’s ~~and~~registered ~~audits~~public ofaccounting ~~our~~firm ~~financial~~pursuant ~~statements~~to ~~for~~rules of the ~~year~~SEC ~~ended~~applicable ~~December~~to ~~31,~~an ~~2014~~Emerging ~~and~~Growth ~~2013~~Company ~~and~~that ~~quarters~~permit ~~ended~~the ~~September~~Company ~~31,~~to ~~June~~provide ~~30,~~only ~~and~~management’s ~~March~~report ~~31,~~in ~~2014~~this ~~and~~annual ~~2013~~report.

34COMPENSATION COMMITTEE REPORT: Because we do not have a compensation committee or a committee performing similar functions, we do not have a compensation committee report. All compensation matters are determined by our board of directors.

~~PART~~ITEM IV9B. OTHER INFORMATION

~~Item 15~~None. ~~Exhibits~~

~~The~~16 ~~following~~Table ~~exhibits are filed as part~~ of ~~this Annual Report.~~Contents

~~Exhibit~~PART ~~31.1: Certification of Chief Executive Officer pursuant to Section 302(a) of the Sarbanes-Oxley Act~~III

~~Exhibit~~Item 3110.~~2: Certification~~ ofDirectors, ~~Chief~~Executive ~~Financial~~Officers, ~~Officer~~Promoters ~~pursuant~~and toControl ~~Section~~Persons ~~302(a)~~ of the ~~Sarbanes-Oxley Act~~Company

~~Exhibit~~DIRECTORS ~~32.1~~AND EXECUTIVE OFFICERS: ~~Certification~~The following table sets forth the names, positions and ages of ~~Chief~~the ~~Executive~~current ~~Officer~~Company Directors and ~~Chief~~Officers. ~~Financial~~Directors ~~Officer~~are ~~under~~elected ~~Section~~during ~~1350~~the asannual ~~Adopted~~shareholders’ ~~Pursuant~~meeting ~~Section~~and ~~906~~serve for one year and until their successors are elected and qualify. Officers are elected by our board of directors and their terms of office are at the ~~Sarbanes-Oxley~~discretion ~~Act~~of our board. None of our Directors is independent per NASDAQ listing standards.

101.INS* XBRL Instance Document

Director/Officer	Age	Position/Office

Chris Hymel	60	Director, President/Treasurer
Malcolm Skolnick	82	Director, Secretary
Ron Stubbers	55	Director, Vice-President
Richard Seltzer	63	Director

~~101~~All directors hold office until the next annual meeting of the shareholders of the Company and until their successors have been duly elected and qualified.~~SCH* XBRL~~ ~~Taxonomy~~The ~~Extension~~Company’s ~~Schema~~Bylaws ~~Document~~provide that the Board of Directors will consist of no less than three members.

~~101.CAL* XBRL~~BIOGRAPHIES: ~~Taxonomy Extension Calculation Linkbase Document~~

~~101~~Chris M.~~DEF* XBRL~~ ~~Taxonomy~~Hymel, ~~Definition~~Ph.D. ~~Linkbase~~(President/Treasurer, ~~Document~~Director): served as a director and its President and Treasurer since its inception. Dr. Hymel previously founded a computer systems/networking consulting and development firm and, later, a medical-legal firm which developed over 60 animations used in litigation support. He also served on the board of a non-profit corporation, Educational Enrichment Center through 2009. Professional experience also includes technology development at the University of Texas, Neurophysiology Research Center, including the development of proprietary neurostimulation, signal generation and data acquisition systems, and control systems engineering for Shell Oil & Shell Development Companies and Johnson Controls, Inc. Dr. Hymel holds a doctorate in biomedical sciences from the University of Texas Health Science Center, Houston as well as bachelors and masters degrees in electrical engineering from Texas A&M University. Dr. Hymel holds multiple patents and has authored a number of scientific / technical publications. Dr. Hymel developed the proprietary Signal Advance technology and successfully demonstrated temporally advanced detection of a range of analog (including bioelectric) signals in his doctorate research completed at the University of Texas Health Science Center in August 2010.

~~101~~Malcolm Skolnick (Secretary, Director): Dr.~~LAB* XBRL~~ ~~Taxonomy~~Skolnick ~~Extension~~received ~~Label~~his ~~Linkbase~~Ph.D. ~~Document~~in physics from Cornell University and J.D. from the University of Houston Law Center. He retired in 2008 after ten years as a Director, President/CEO of CytoGenix, Inc., a publicly traded, development stage biotechnology firm in Houston Texas. Prior to joining CytoGenix, Dr. Skolnick, a tenured professor, held academic positions in the Medical School, the Graduate School of Biomedical Sciences and the School of Public Health (SPH) of the University of Texas Health Science Center, Houston (UT Health). In addition to his service as a Department Chair in the Medical School and professorial duties, Dr. Skolnick directed the UT Health Office of Technology Management, overseeing the University’s activities in protecting and licensing its technology portfolio.

~~101.PRE* XBRL~~17 ~~Taxonomy~~Table ~~Extension~~of ~~Presentation Linkbase Document~~Contents

* Furnished herewithDr. ~~XBRL~~Skolnick ~~(Extensible~~headed ~~Business~~the ~~Reporting~~UT ~~Language)~~Health ~~information~~Neurophysiology isResearch ~~furnished~~Center and ~~not~~served ~~filed~~as orprincipal ainvestigator ~~part~~ of aseveral ~~registration~~clinical ~~statement~~trials orin ~~prospectus~~related ~~for~~to ~~purposes~~pain management, smoking cessation and reduction of ~~Sections~~withdrawal 11symptoms orin 12drug addiction. He also serves as Director and Vice President of the ~~Securities~~Southwest ~~Act~~Health ofTechnology ~~1933~~Foundation, isResolution ~~deemed~~Forum, ~~not~~Inc., ~~filed~~Responsible ~~for~~Community ~~purposes~~Design ofInternational, ~~Section~~Inc., 18and ofHudson ~~the~~Forest ~~Securities~~Homeowners’ ~~Exchange~~Association. ~~Act~~He ofhas ~~1934~~served as an expert witness in intellectual property, product liability, and ~~otherwise~~accident reconstruction matters. Dr. Skolnick is ~~not~~a ~~subject~~registered patent attorney, patented inventor and is licensed to ~~liability~~practice ~~under~~law ~~these~~in ~~sections~~the State of Texas. In addition to his service on various corporate boards, since his retirement from CytoGenix, Inc., he has been active in patent prosecution and licensing for selected clients and has been an invited lecturer at several local universities.

35Ron A, Stubbers (Vice-President, Director): Mr. Stubbers has been developing and manufacturing electronic biomedical devices for over 20 years, much of it while VP of Engineering and VP of Operations for Neuroscan, Inc. and its successor Compumedics, USA from 1991-2003, and aDEPtas, Inc. and its successor InGeneron, Inc. from 2004-Present. His experience includes development and production of medical devices ranging from neurostimulation systems to EEG acquisition and analysis systems. He has also worked in the areas of product design and manufacturing engineering, quality, regulatory and technical support for startup companies. Mr. Stubbers has managed corporate ISO/EN/QSR quality management systems requirements and compliance and European CE and FDA 510K Class II as well as other regulatory approvals for world-wide medical device distribution. Mr. Stubbers received his bachelor’s degree in electrical engineering from the University of Idaho in 1985, completed graduate coursework at the University of Texas, Graduate School of Biomedical Sciences and at Rice University, and completed his MBA at the University of Houston (2013).

~~SIGNATURES~~Richard C. Seltzer (Director): Mr. Seltzer received his J.D. from South Texas College of Law in 1981 and his LL.M. in Taxation from the University of Florida in 1982. Mr. Seltzer has been in private practice for more than thirty years representing both established and startup businesses in acquisitions and mergers, financial and tax issues, contractual matters, shareholder disputes, real estate acquisitions and general business litigation in Texas State Courts. His practice includes arranging viable capital infusions for ongoing businesses, negotiating business and real estate related contracts. He has handled the licensing of proprietary information for a non-profit organization in Texas. He also continues to successfully represent numerous taxpayer corporations and individuals before the Internal Revenue Service, including both its Appellate and Collection Divisions as well as representing taxpayers for matters filed with the U.S. Tax Court. For more than fifteen years Mr. Seltzer has been a frequent invited speaker covering general business topics at the People’s Law School in conjunction with the University of Houston Law School. He is also an approved mediator in the State of Texas having received his certification in 2008.

InMr. ~~accordance~~Seltzer ~~with~~has ~~the~~continued ~~requirements~~to serve as a member of the ~~Exchange~~Board ~~Act~~of Directors of Bridges to Life, a nonprofit organization in Houston, since 2003. He was appointed in 2011 as a member of the ~~registrant~~Board ~~caused~~of ~~this~~Directors ~~report~~of toSTARBASE, beInc., ~~signed~~a onfederally ~~its~~funded ~~behalf~~educational byprogram working in conjunction with the ~~undersigned~~Department of Defense and the National Guard that works with upper elementary school students particularly interested in math, ~~thereunto~~science, ~~duly~~engineering ~~authorized~~and technology related programs. In addition, Mr. Seltzer serves on the Boards of

Dated: March 24, 2015	SIGNAL ADVANCE, INC.
	By: /s/ Chris M. Hymel
	Chris M. Hymel, President/Treasurer

Directors of the following Texas corporations: Atlas Management, Inc. (appointed in 2000), Innovative Tooling and Accessories, Inc. (appointed in 2007), Intuitec, Inc. (appointed in 2003), Milsob Properties, Inc. (appointed in 2008). He has also served on the Board of Directors of Delta Shaver Company, Inc., a Delaware corporation since 2011.

~~Pursuant~~AUDIT toCOMMITTEE: ~~the~~We ~~requirements~~do ofnot ~~the~~have ~~Securities~~an ~~Act~~audit ofcommittee ~~1933~~financial expert, ~~this~~as ~~Registration~~the ~~Statement~~cost ~~has~~related ~~been~~to ~~signed~~retaining bya ~~the~~financial ~~following~~expert ~~persons~~at inthis time is prohibitive. Further, our President has the ~~capacities~~requisite financial experience and asknowledge, ofthus, we believe the ~~dates~~services ~~indicated~~of a financial expert are not warranted.

SIGNATURE	TITLE	DATE
/s/ Chris M. Hymel	Chairman: Board of Directors, President and Treasurer	March 24, 2015
Chris M. Hymel	(Principal Executive, Financial and Accounting Officer)
/s/ Malcolm H. Skolnick	Member: Board of Directors, Secretary	March 24, 2015
Malcolm H. Skolnick
/s/ Richard C. Seltzer	Member of the Board of Directors	March 24, 2015
Richard C. Seltzer

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~~Supplemental~~SIGNIFICANT ~~Information~~EMPLOYEES: toWe behave ~~Furnished~~no ~~With~~employees ~~Reports~~other ~~Filed~~than ~~Pursuant~~our todirectors/officers ~~Section~~of ~~15(d)~~which ofonly the ~~Act~~President/Treasurer bydevotes ~~Registrants~~full ~~Which~~time ~~Have~~to ~~Not~~company ~~Registered~~matters. ~~Securities~~Others ~~Pursuant~~devote time as needed. We intend to ~~Section~~hire 12employees ofon ~~the~~an ~~Act~~as needed basis.

AsFAMILY ofRELATIONSHIPS: ~~the~~There ~~date~~are ~~of filing of this report,~~ no ~~annual~~family ~~report~~relationships oramong ~~proxy~~our ~~material~~directors, ~~has~~executive ~~been~~officers, ~~sent~~director tonominees ~~security holders. An annual report and/~~or ~~proxy~~significant material will be furnished to security holders subsequent to the filing of the annual report of this Form and the registrant shall furnish copies of such material to the Commission when it is sent to security holdersemployees.

36Item 11. Executive Compensation

The executive compensation disclosure provided satisfies the requirements applicable to emerging growth companies, as defined in the JOBS Act. The summary compensation table below shows certain compensation information paid for services rendered in all capacities to us by our principal executive officer and by each other executive officer whose total annual salary and bonus exceeded $100,000 during years ended December 31, 2016, 2015 and 2014. Other than as set forth below, no executive officer’s total annual compensation exceeded $100,000 during our last fiscal period.

SUMMARY COMPENSATION TABLE:

Name & Position	Year or Period	Salary		Bonus		Stock Awards (1)		Options Awards		Non-Equity Incentive Plan Compensation		Non-Qualified Deferred Compensation Earnings		All Other Compensation (2)		Total

C Hymel Pres/Treas	2016		0		0	$	108,000		0		0		0	$	801	$	108,801
C Hymel Pre./Treas	2015		0		0	$	108,000		0		0		0	$	3,086	$	111,086
C Hymel Pres/Treas	2014		0		0	$	108,000		0		0		0	$	2,210	$	110,210

(1) Non-cash compensation: Equity issued for services rendered

(2) Reimbursement of medical and professional development expenses

The Company entered into a consulting agreement with Dr. Chris M. Hymel, the Company President, whereby he was compensated at $108,000 per year in 2016, 2015 and 2014, plus limited reimbursement of medical and professional development expenses. Dr. Hymel is expected to devote essentially full-time (at least 40 hours/week) on activities related to the Company. The term of the agreement is year-to-year but may be terminated by giving one month’s notice. Eligible medical and professional development expenses are either paid or reimbursed in cash and annual compensation for services rendered has been in the form of equity, specifically common stock, for years ended December 31, 2016, 2015 and 2014.

In year ending December 31, 2015, Mr. Stubbers received $12,750 in the form of equity (common stock) in exchange for services. In additional, in the same period, Mr. Seltzer and Dr. Skolnick each received $9,000 in the form of equity (common stock) in exchange for services. Other than as described above, all directors and executive officers received well under than $15,000 compensation in the form of equity (common stock) in exchange for their services. No executive officers received a bonus or deferred compensation.

In the year ended December 31, 2016, no Director received compensation, either in the form of cash or equity (common stock) in exchange for services, other than as described above. Further, no executive officers received a bonus or deferred compensation.

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Other Executive Officer Compensation (to date):

Outstanding Equity Awards:		None
Option Exercises/Stock Vested:		None
Pension Benefits:		None
Non-qualified Deferred Compensation:		None
All Other Compensation:		None
Perquisites:		None

There are no employment contracts, compensatory plans or arrangements (except as referenced above for the Company President), including payments to be received from the Company with respect to any executive officer of the Company which would in any way result in payments to any such person because of his or her resignation, retirement or other termination of employment with the Company or its subsidiaries, any change in control of the Company or a change in the person’s responsibilities following a change in control of the Company. Nor are there any agreements or understandings for any director or officer to resign at the request of another person. None of the Company’s directors or executive officers is acting on behalf of or will act at the direction of any other person.

COMPENSATION PURSUANT TO PLANS: There is no retirement, pension, profit sharing, or other plan covering any of our officers and directors. The Company has adopted no formal stock option plans for our officers, directors and/or employees. SA reserves the right to adopt one or more stock options plans in the future. Presently, there is no plan to issue additional equity in the Company or options to acquire the same to our officers, directors or their affiliates or associates except for compensation of Director and Officers as described previously.

CORPORATE GOVERNANCE: Currently, the Company has no formal Audit or Compensation Committee.

Item 12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters

The Company is authorized to issue 100,000,000 shares of common stock, with no par value. Holders of common stock are entitled to one vote per share on all matters subject to shareholder vote. The common stock has no cumulative, preemptive or other subscription rights. All of the presently issued shares of common stock are fully paid and non-assessable. The Board of Directors may declare dividends payable to holders of common stock out of legally available funds. If the Company is liquidated or dissolved, holders of shares of common stock will be entitled to share ratably in any assets of the Company remaining after satisfaction of all of its liabilities.

As of December 31, 2015, 10,655,077 shares had been issued to 177 shareholders of record. As of December 31, 2016, 12,407,342 shares had been issued to 180 shareholders of record.

The following table sets forth the number of shares of common stock that are beneficially owned as of December 31, 2016 by (i) each person known by us to be the beneficial owner of more than 5% of the outstanding shares of our common stock, (ii) each of our directors and executive officers, (iii) all officers and directors as a group and, (iv) all officers and directors and each person known by us to be the beneficial owner of more than 5% of the outstanding shares of our common stock as a group. The persons and entities named in the table have sole voting and sole investment power with respect to the shares set forth opposite the stockholder’s name, subject to community property laws, where applicable.

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Name of Beneficial Owner	Title of Class	Amount/Nature of Beneficial Ownership(1)		Percent of Class (4)
Chris Hymel, Officer/Director (2,3)	Common		5,163,780		41.6	%
Malcolm Skolnick, Officer/Director (2,3)	Common		338,334		2.7	%
Ron Stubbers, Officer/Director (2,3)	Common		286,250		2.3	%
Richard C. Seltzer, Director (3)	Common		314,765		2.5	%
Cede & Co.	Common		1,547,251		12.5	%
Officers/Directors as a group (4 total)	Common		6,103,129		49.2	%
Officers/Directors & Shareholders owning > 5% as a group (5 total)	Common		7,650,380		61.7	%

(1) Beneficial ownership is determined in accordance with SEC rules, and includes any shares as to which the stockholder has sole or shared voting power or investment power. Any indication herein, regarding beneficial ownership, is not an admission, that he, she or it is a direct or indirect beneficial owner of those shares.

(2) The address for all Directors/Officers: 2520 CR 81, Rosharon, TX 77583

(3) Includes shares held by spouses and minor children.

(4) The percent of class based on 12,407,342 shares common stock issued and outstanding as of December 31, 2016.

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS: As of December 31, 2016 and 2015, the Company owed its President, Chris M Hymel, $12,380 and $4,704, respectively, in the form of an unsecured loan (Line of Credit). The note is due on demand and bears 2.5% interest per quarter. The Company currently leases office space, from its President, on a month to month basis at a rate of $700 per month. The Company obtained rights to the intellectual property though an assignment agreement with its President (discussed in greater detail in Note B - Intellectual Property of the Financial Statements).

Other than the President’s compensation, related transactions, discussed previously, since the company’s inception, there has not been, nor is there currently proposed, any transaction or series of similar transactions with related parties to which the Company was or will be a party:

1) In which the amount involved exceeds $120,000; and

2) In which any director, executive officer, shareholder who beneficially owns 5% or more of SA common stock, or any member of their immediate family, had or will have a direct or indirect material interest.

DIRECTOR INDEPENDENCE The Company has not established its own definition for determining whether its directors and nominees for directors are ‘independent’ nor has it adopted any other standard of independence employed by any national securities exchange or inter-dealer quotation system. None of the Company’s current directors are considered independent as determined by the NASDAQ listing standards.

Item 14. Principal Accountant Fees and Services

As of the date of this report, the Company has incurred $17,800 in fees to our principal independent accountants for professional services rendered in connection with the audits of our financial statements for the years ended December 31, 2016 and 2015.

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PART IV

Item 15. Exhibits

The following exhibits are filed as part of this Annual Report.

Exhibit 31.1:	Certification of Chief Executive Officer pursuant to Section 302(a) of the Sarbanes-Oxley Act

Exhibit 31.2:	Certification of Chief Financial Officer pursuant to Section 302(a) of the Sarbanes-Oxley Act

Exhibit 32.1:	Certification of Chief Executive Officer and Chief Financial Officer under Section 1350 as Adopted Pursuant Section 906 of the Sarbanes-Oxley Act

101.INS*	XBRL Instance Document
101.SCH*	XBRL Taxonomy Extension Schema Document
101.CAL*	XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF*	XBRL Taxonomy Definition Linkbase Document
101.LAB*	XBRL Taxonomy Extension Label Linkbase Document
101.PRE*	XBRL Taxonomy Extension Presentation Linkbase Document

________________

* Furnished herewith. XBRL (Extensible Business Reporting Language) information is furnished and not filed or a part of a registration statement or prospectus for purposes of Sections 11 or 12 of the Securities Act of 1933, is deemed not filed for purposes of Section 18 of the Securities Exchange Act of 1934, and otherwise is not subject to liability under these sections.

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SIGNATURES

In accordance with the requirements of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Dated: March 4, 2019	SIGNAL ADVANCE, INC.

	By:	/s/ Chris M. Hymel
		Chris M. Hymel, President/Treasurer

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and as of the dates indicated.

Signature	Title	Date

/s/ Chris M. Hymel	Chairman: Board of Directors, President and Treasurer	March 4, 2019
Chris M. Hymel	(Principal Executive, Financial and Accounting Officer)

/s/ Malcolm H. Skolnick	Member: Board of Directors,	March 4, 2019
Malcolm H. Skolnick	Secretary

/s/ Richard C. Seltzer	Member of the Board of Directors	March 4, 2019
Richard C. Seltzer

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