UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

~~WASHINGTON~~Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): ~~February 3~~March 30, 2026

SANGAMO THERAPEUTICS, INC.

(Exact name of registrant as specified in its charter)

Delaware

~~000-30171~~

~~68-0359556~~

000-30171

68-0359556

(State or other jurisdiction of incorporation)

(Commission File Number)

(IRS Employer Identification No.)

(State or other jurisdiction ofincorporation)

(CommissionFile Number)

(IRS EmployerID Number)

501 Canal Blvd., Richmond, California 94804

(Address of principal executive offices) (Zip Code)

(510) 970-6000

(Registrant’s telephone number, including area code)

Not Applicable

(Former ~~name~~Name or ~~former~~Former ~~address~~Address, if ~~changed~~Changed ~~since~~Since ~~last~~Last ~~report~~Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:


☐			Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)


☐			Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)


☐			Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))


☐			Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, $0.01 par value per share

SGMO

Nasdaq Capital Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 1 2.0102 ~~Entry~~Results ~~into~~of aOperations ~~Material~~and ~~Definitive~~Financial ~~Agreement~~Condition.

~~Underwritten~~On ~~Offering~~March 30, 2026, Sangamo Therapeutics, Inc. (“Sangamo”) issued a press release announcing its financial results for the year ended December 31, 2025 (the “Press Release”).

OnA ~~February 3,~~copy ~~2026,~~of ~~Sangamo Therapeutics, Inc. (“Sangamo” or~~ the ~~“Company”)~~Press ~~entered~~Release ~~into~~is anfurnished ~~underwriting~~hereto ~~agreement~~as ~~(the~~Exhibit ~~“Underwriting Agreement”) with Cantor Fitzgerald & Co~~99.1 and ~~Wells~~is ~~Fargo~~incorporated ~~Securities,~~by ~~LLC,~~reference asherein. ~~representatives~~The ofinformation ~~the~~contained ~~several~~in ~~underwriters~~this ~~named~~Item ~~therein~~2.02 ~~(collectively, the “Underwriters”), relating to the issuance~~ and ~~sale~~in (the ~~“Offering”)~~Press ofRelease ~~35,190,292~~furnished ~~shares~~as ofExhibit ~~the Company’s common stock, par value $0~~99.011 ~~per~~to ~~share~~this ~~(the~~Current ~~“Common~~Report ~~Stock”),~~on ~~and~~Form ~~pre~~8-~~funded~~K ~~warrants~~shall tonot ~~purchase~~be ~~17,787,033~~deemed ~~shares of Common Stock (the~~ “~~Pre-Funded Warrants~~filed”), ~~together~~for ~~with~~purposes ~~accompanying~~of ~~warrants~~Section to18 ~~purchase 52,977,325 shares~~ of ~~Common Stock (~~the ~~“Purchase~~Securities ~~Warrants”~~Exchange ~~and~~Act ~~together~~of ~~with~~1934, ~~the~~as ~~Pre-Funded Warrants~~amended, ~~the~~or ~~“Warrants”).~~otherwise ~~The~~subject ~~combined~~to ~~offering~~the ~~price~~liabilities of ~~each~~that ~~share~~Section ofor ~~Common~~Sections ~~Stock~~11 and ~~accompanying~~12(a)(2) ~~Purchase~~of ~~Warrant~~the isSecurities ~~$0.4719.~~Act ~~The combined offering price~~ of ~~each~~1933, ~~Pre-Funded~~as ~~Warrant and accompanying Purchase Warrant is $0~~amended.~~4619.~~ The ~~Common~~information ~~Stock~~contained ~~and~~in ~~Pre-Funded~~this ~~Warrants~~Item ~~are~~2.02 ~~being~~and ~~sold~~ in ~~combination~~the ~~with~~Press anRelease ~~accompanying~~furnished ~~Purchase~~as ~~Warrant~~Exhibit 99.1 to ~~purchase~~this ~~one~~Current ~~share~~Report ofon ~~Common~~Form ~~Stock~~8-K ~~issued~~shall ~~for~~not ~~each~~be ~~share~~incorporated ofby ~~Common~~reference ~~Stock~~into orany ~~Pre-Funded~~filing ~~Warrant~~with ~~sold. All of~~ the ~~securities~~Securities inand ~~the~~Exchange ~~Offering~~Commission ~~are~~made ~~being sold~~ by ~~the~~Sangamo ~~Company.~~whether ~~The~~made ~~gross~~before ~~proceeds~~or toafter the ~~Company~~date ~~from the Offering~~hereof, ~~before~~regardless ~~deducting~~of ~~underwriting~~any ~~discounts~~general ~~and~~incorporation ~~estimated~~language ~~offering~~in ~~expenses,~~such ~~is expected to be approximately $25~~filing.~~0 million.~~ ~~The Offering is expected to close on February 4, 2026, subject to satisfaction of customary closing conditions.~~

Each Pre-Funded Warrant will have an initial exercise price per share of $0.01, subject to certain adjustments. The Pre-Funded Warrants will be exercisable immediately and may be exercised at any time until all of the Pre-Funded Warrants are exercised in full. A holder (together with its affiliates and other attribution parties) may not exercise any portion of a Pre-Funded Warrant to the extent that immediately prior to or after giving effect to such exercise the holder would own more than 9.99% of the Company’s outstanding Common Stock immediately after exercise, which percentage may be changed at the holder’s election to a lower or higher percentage not in excess of 19.99% (if exceeding such percentage would result in a change of control under Nasdaq Listing Rule 5635(b) or any successor rule) upon 61 days’ notice to the Company subject to the terms of the Pre-Funded Warrants.

Each Purchase Warrant will have an initial exercise price per share of $0.4719, subject to certain adjustments. The Purchase Warrants will be exercisable six months after the date of issuance and may be exercised thereafter at any time until expiration five and a half years after the date of issuance. A holder (together with its affiliates and other attribution parties) may not exercise any portion of a Purchase Warrant to the extent that immediately prior to or after giving effect to such exercise the holder would own more than 4.99% of the Company’s outstanding Common Stock immediately after exercise, which percentage may be changed at the holder’s election to a lower or higher percentage not in excess of 19.99% (if exceeding such percentage would result in a change of control under Nasdaq Listing Rule 5635(b) or any successor rule) upon 61 days’ notice to the Company subject to the terms of the Purchase Warrants.

The Offering is being made pursuant to Sangamo’s effective registration statement on Form S-3 (Registration Statement No. 333-283179) previously filed with the Securities and Exchange Commission (the “SEC”) and a prospectus supplement thereunder.

The Underwriting Agreement contains customary representations, warranties and agreements by the Company, customary conditions to closing, indemnification obligations of the Company and the Underwriters, including for liabilities arising under the Securities Act of 1933, as amended (the “Securities Act”), other obligations of the parties and termination provisions. The representations, warranties and covenants contained in the Underwriting Agreement were made only for the purposes of such agreement and as of specific dates, and were solely for the benefit of the parties to such agreement.

The foregoing descriptions of the terms of the Underwriting Agreement and Warrants are each qualified in their entirety by reference to the Underwriting Agreement, form of Pre-Funded Warrant and form of Purchase Warrant, respectively, which are attached as Exhibit 1.1, Exhibit 4.1 and Exhibit 4.2 hereto, respectively, and incorporated by reference herein.

A copy of the legal opinion of Cooley LLP relating to the validity of the issuance and sale of the securities in the Offering is attached as Exhibit 5.1 hereto.

Warrant Amendment

In connection with the Offering, on February 3, 2026, the Company entered into a warrant amendment (the “Warrant Amendment”) pursuant to which Sangamo agreed, concurrently with the closing of the Offering, to reduce the exercise price of outstanding common stock warrants issued on March 26, 2024 and held by the investor in the Offering to purchase 23,809,523 shares of common stock from $1.00 to $0.4719 (the “Repriced Warrants”). The Repriced Warrants will become exercisable six months from the closing date of the Offering. In connection with the reduction in exercise price, the Company has additionally agreed to extend the expiration date of the Repriced Warrants to be five and a half years from the closing of the Offering. Other than as described herein, the terms of the Repriced Warrants remain the same and unchanged.

Item 3.02 Unregistered Sales of Equity Securities.

The information set forth in Item 1.01 of this Current Report on Form 8-K relating to the Warrant Amendment is incorporated by reference herein. The Warrant Amendment may be deemed to involve an exchange of securities exempt from registration pursuant to Section 3(a)(9) of the Securities Act.

Forward-Looking Statements

This report contains forward-looking statements, including, without limitation, statements relating to Sangamo’s expectations regarding the completion of the Offering. These forward-looking statements are based upon Sangamo’s current expectations. Actual results could differ materially from these forward-looking statements as a result of certain factors, including, without limitation, risks and uncertainties related to the satisfaction of customary closing conditions related to the Offering and other risks detailed in Sangamo’s filings with the SEC, including Sangamo’s Annual Report on Form 10-K for the year ended December 31, 2024, Quarterly Report on Form 10-Q for the quarter ended September 30, 2025 and in the prospectus supplement relating to the offering. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this report. Sangamo undertakes no duty to update such information except as required under applicable law.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits .

ExhibitNumber	Description
ExhibitNo.		Description
1.1	Underwriting Agreement, dated February 3, 2026, by and between Sangamo Therapeutics, Inc. and Cantor Fitzgerald & Co. and Wells Fargo Securities, LLC, as representatives of the underwriters named therein.
99.1		Press Release regarding financial results dated March 30, 2026
4.1	Form of Pre-Funded Warrant to Purchase Common Stock.
104		Cover Page Interactive Data File (embedded within the Inline XBRL document)
4.2	Form of Purchase Warrant to Purchase Common Stock.
5.1	Opinion of Cooley LLP.
23.1	Consent of Cooley LLP (included in Exhibit 5.1).
104	Cover Page Interactive Data File (the cover page XBRL tags are embedded within the Inline XBRL document).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

SANGAMO THERAPEUTICS, INC. By: /s/ SCOTT B. WILLOUGHBY Name: Scott B. Willoughby Title: Chief Legal Officer and Corporate Secretary

SANGAMO THERAPEUTICS, INC.

Dated: March 30, 2026

By:

/s/ SCOTT B. WILLOUGHBY

Name:

Scott B. Willoughby

Title:

Chief Legal Officer and Corporate Secretary

Dated: February 4, 2026

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