UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): ~~October~~November 1019, 2025

ZYVERSA THERAPEUTICS, INC. (Exact name of registrant as specified in its charter)

(Exact name of registrant as specified in its charter)

Delaware

001-41184

86-2685744

(State or other jurisdiction

of incorporation)

(Commission

File Number)

(IRS Employer

Identification No.)

2200 N. Commerce Parkway, Suite 208, Weston, Florida		33326
(Address of principal executive offices)		(Zip Code)

Registrant’s telephone number, including area code:

(754) 231-1688

Not Applicable (Former name or former address, if changed since last report.)

(Former name or former address, if changed since last report.)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐	Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐	Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐	Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐	Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class		Trading symbol		Name of each exchange on which registered
Common Stock, par value $0.0001 per share		ZVSA		~~—(1)~~*

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐☒

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

~~(1)~~* The ~~Company~~company’s common stock is quoted on the OTCQB® Venture Market under the symbol “ZVSA.”

Item 52.02 ~~Departure~~Results of ~~Directors~~Operations orand ~~Certain~~Financial ~~Officers; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.~~Condition

On ~~October~~November 1019, 2025, ~~Pablo Guzman, M.D., resigned as Chief Medical Officer and Senior Vice President of Medical Affairs of~~ ZyVersa Therapeutics, Inc. (the “Company”)~~. Dr. Guzman first joined~~ ~~the~~issued ~~Company~~a inpress ~~January~~release ~~2015,~~announcing ~~following~~its ~~more~~unaudited ~~than~~financial 35results ~~years~~for ofthe ~~practicing~~quarter ~~medicine/interventional~~ended ~~cardiology~~September in30, ~~South~~2025. ~~Florida~~A ~~and~~copy ~~serving as a managing partner~~ of ~~Cardiology~~the ~~Associates~~press ofrelease is ~~Fort~~furnished ~~Lauderdale.~~herewith ~~Dr.~~as ~~Guzman~~Exhibit ~~resigned to spend more time with his family and to travel~~99.1.

The information furnished under Item 2.02 in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section, and shall not be incorporated by reference in any filing under the Securities Act of 1933, as amended, except as expressly set forth by specific reference in such a filing.

Item 9.01

Financial Statements and Exhibits.

Exhibit No.		Description
99.1		Press Release, dated November 19, 2025
104		Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date: October 15, 2025	ZYVERSA THERAPEUTICS, INC.
Date: November 19, 2025	ZYVERSA THERAPEUTICS, INC.
	/s/ Stephen Glover
	Stephen Glover
	Chief Executive Officer

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