UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT ~~REPORT~~ ~~Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934~~REPORT

~~Date~~Pursuant to ofSection ~~Report~~13 or 15(~~Date~~d) of ~~earliest~~the ~~event~~Securities ~~reported):~~Exchange ~~July~~Act ~~31,~~of ~~2025~~1934

Date of Report (Date of earliest event reported): October 8, 2025

Milestone Scientific Inc.

(Exact name of registrant as specified in its charter)

Delaware

(State or other jurisdiction

of incorporation)

001-14053

(Commission

File Number)

13-3545623

(IRS Employer

Identification No.)

~~425~~220 ~~Eagle~~South ~~Rock~~Orange Avenue, ~~Suite~~Livingston ~~403~~Corporate ~~Roseland~~Park Livingston, New Jersey (Address of principal executive offices) ~~07068~~070340 (Zip Code)

Registrant’s telephone number, including area code (973) 535-2717

(Former name or former address, if changed since last report.)

Securities registered pursuant to Section 12(b) of the Act:

Title of each class Trading Symbol(s) Name on exchange on which registered Common Stock MLSS NYSE American

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instructions A.2. below):

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) ☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) ☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) ☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act ☐

Item 5 3.0201 — ~~Departure~~ Notice of ~~directors~~Delisting or ~~certain~~Failure ~~officers;~~to ~~election~~Satisfy ofa ~~directors;~~Continued ~~appointment~~Listing ofRule ~~certain~~or ~~officers~~Standard; ~~compensatory~~Transfer ~~arrangements~~ of ~~certain officers~~Listing

~~Effective~~On October ~~July 31~~8, 2025, ~~the Board of Directors of~~ Milestone Scientific Inc. (“the “Company”) ~~appointed~~received ~~Eric Hines as President and Chief Executive Officer, and as~~ a ~~director~~letter offrom ~~the~~NYSE ~~Company.~~American ~~From~~LLC ~~July~~(“NYSE ~~31,~~American” or ~~2025 through December 31, 2025 (~~the “~~Initial Term~~Exchange”), ~~Mr.~~stating ~~Hines~~that ~~will~~the beCompany ~~entitled~~is tonot ~~base~~in ~~compensation~~compliance atwith the ~~rate~~continued oflisting ~~$15,000~~standards ~~per~~as ~~month.~~outlined ~~From~~in ~~January 1~~Section(s) 1003(a)(ii), ~~2026,~~and ~~subject~~(iii) toof ~~Mr.~~the ~~Hines’s~~NYSE ~~continued~~American ~~employment at the~~ Company byGuide ~~mutual agreement~~ (the “~~Extended~~Company ~~Term~~Guide”)~~, Mr~~. ~~Hines~~To ~~will~~maintain beits ~~entitled~~listing, tothe ~~base~~Company ~~compensation~~must submit ata ~~the~~plan ~~rate~~ of ~~$25,000~~compliance ~~per~~by ~~month.~~November In7, ~~addition to his base compensation~~2025, ~~Mr.~~outlining ~~Hines will be granted options (~~the ~~“Signing~~actions ~~Bonus~~it ~~Options”)~~has ~~for~~taken anor ~~aggregate~~will oftake ~~2,000,000~~to ~~shares~~regain ofcompliance. ~~Common~~If ~~Stock~~the ofplan is accepted, the Company~~. The~~ ~~exercise~~may ~~price~~be ofable ~~the~~to ~~Signing~~continue ~~Bonus~~its ~~Options~~listing but will be ~~the~~subject ~~fair~~to ~~market~~periodic ~~value~~reviews ofby ~~shares~~the ofExchange. ~~Common~~If ~~Stock of~~ the ~~Company~~plan onis ~~the~~not accepted ~~date~~or ofif ~~grant.~~it ~~Ten~~is ~~percent~~accepted ~~(10%)~~but of the ~~Signing~~Company ~~Bonus~~fails ~~Options~~to ~~will~~comply ~~vest~~with on the ~~date~~continued oflisting ~~grant~~standards ~~and~~by ~~the~~April ~~remaining~~8, ~~ninety~~2027, ~~percent~~or ~~(90%)~~if ~~will~~the ~~vest~~Company does innot ~~three~~make ~~(3)~~progress ~~equal~~consistent ~~annual~~with ~~installments~~the ~~of 600~~plan,~~000~~ ~~shares~~the ~~each.~~Exchange Inwill ~~addition,~~initiate itdelisting isprocedures ~~expected~~as ~~that Mr~~appropriate. ~~Hines~~The ~~would~~Company’s management beis ~~entitled~~pursuing options to ~~receive~~address anthe ~~annual~~deficiency ~~incentive~~and ~~bonus,~~intends ~~comprised~~to ofsubmit ~~(i) separate performance-based bonuses; and (ii)~~ a ~~discretionary~~compliance ~~bonus,~~plan ~~each~~on asor ~~determined~~before by the ~~Company’s~~deadline ~~Compensation~~set ~~Committee,~~by ~~in its sole discretion~~the Exchange.

Mr. Hines most recently served as President of North America at Ex Libris Group (September 2014 - June 2021), a global provider of cloud-based solutions for higher education and libraries. From June 2021 to July 2025, Mr. Hines was involved in providing consulting services for Alethea, a technology start-up company, and also invested in commercial and personal real estate ventures. Prior to his role at Ex Libris Group, Mr. Hines held various roles at NICE Systems (October 2004-June 2014), a multinational company that designs and manufactures smart home security and automation products. Mr. Hines served as Senior Director of Sales at NICE Systems from October 2004 to November 2005, and subsequently served as Vice President of several North American divisions of NICE Systems from November 2005 through June 2014. Prior thereto, Mr. Hines served as Regional Director of Sales at AMDOCS Clarify CRM (October 2003- October 2004), a provider of customer relationship management (CRM) solutions to the communications industry.

Mr. Hines received a BS in Chemistry from Wake Forest University in 1989 and an MBA in International Business from Xavier University in 1996.

Item 8.01 - Other Events

On August 1, 2025, the Company issued a press release announcing the appointment of Mr. Hines as Chief Executive Officer. The press release is attached hereto as Exhibit 99.1.

Item 9.01 Financial Statements and Exhibits

(d) Exhibits

99.1 Press Release August 1, 2025

104 Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	MILESTONE SCIENTIFIC INC.
	Milestone Scientific Inc.
Dated: August 5, 2025	By:	/s/ Neal Goldman
Dated: October 14, 2025	By:	/s/ Eric Hines
		Neal Goldman
		Eric Hines
		Interim Chief Executive Officer
		Chief Financial Officer

Filing Compare · MILESTONE SCIENTIFIC INC.