Upstream Bio, Inc.·4

Mar 17, 4:59 PM ET

Houghton Adam 4

4 · Upstream Bio, Inc. · Filed Mar 17, 2026

Research Summary

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Upstream Bio CBO Adam Houghton Sells 699 Shares

What Happened Adam Houghton, Chief Business Officer of Upstream Bio, sold 699 shares of UPB on 2026-03-16 at $9.29 per share for a total of about $6,494. The sale was reported on a Form 4 filed 2026-03-17 and reflects shares disposed to cover tax withholding related to vesting restricted stock units, not an open discretionary sale.

Key Details

  • Transaction date and price: 2026-03-16 — 699 shares sold at $9.29 each.
  • Total value: Approximately $6,494.
  • Shares owned after transaction: Not disclosed in the provided filing summary.
  • Footnote: Sale was automatic under the issuer's "sell-to-cover" policy to satisfy tax withholding on RSU vesting; the sale was not at the reporting person's discretion.
  • Filing timeliness: Form 4 filed 2026-03-17 (within the typical reporting window).

Context Sell-to-cover transactions are routine when restricted stock units vest — a portion of shares are automatically sold to cover taxes. Such automatic sales are generally administrative and do not necessarily indicate insider views on the company's outlook.

Insider Transaction Report

Form 4
Period: 2026-03-16
Houghton Adam
Chief Business Officer
Transactions
  • Sale

    Common Stock

    [F1]
    2026-03-16$9.29/sh699$6,49424,301 total
Footnotes (1)
  • [F1]The Issuer has adopted a "sell-to-cover" policy to satisfy the tax withholding obligations of the Reporting Person. The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.
Signature
/s/ Allison Ambrose, Attorney-in-Fact|2026-03-17

Documents

1 file
  • 4
    ownership.xmlPrimary

    4