UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): ~~June~~July 227, 2023

Horizon Therapeutics Public Limited Company

(Exact name of registrant as specified in its charter)

Ireland	001-35238	~~98-1195602~~Not Applicable
(State or other jurisdiction of incorporation)	(Commission File No.)	(IRS Employer Identification No.)
(State or other jurisdictionof incorporation)	(CommissionFile No.)	(IRS EmployerIdentification No.)

70 St. Stephen’s Green, Dublin 2, D02 E2X4, Ireland (Address of principal executive offices)

~~(Address~~Registrant’s oftelephone ~~principal~~number, ~~executive~~including ~~offices)~~area code: 011-353-1-772-2100

Registrant’s telephone number, including area code: 00-353-1-772-2100

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐	Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐	Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐	Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐	Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class		TradingSymbol(s)		Name of each ~~exchange~~exchangeon on which registered
Ordinary shares, nominal value $0.0001 per share		HZNP		The Nasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 or Rule 12b-2 of the Securities Exchange Act of 1934.

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 85.0107 ~~Other~~Submission ~~Events~~of Matters to a Vote of Security Holders.

AsSet ~~previously~~forth ~~disclosed,~~below onare December 11, 2022, Horizon Therapeutics plc (“Horizon”), Amgen Inc. (“Amgen”) and Pillartree Limited, a wholly owned subsidiary of Amgen (“Acquirer Sub”), entered into a Transaction Agreement pursuant to which, among other things, Acquirer Sub will acquire the ~~entire~~results ~~issued ordinary share capital~~ of ~~Horizon (~~the ~~“Acquisition”)~~matters ~~through~~submitted for a ~~court-sanctioned~~vote ~~scheme~~ of ~~arrangement~~shareholders ~~under~~at ~~Chapter~~our 12023 ofAnnual ~~Part~~General 9Meeting of ~~the~~Shareholders ~~Irish~~held ~~Companies~~on ~~Act~~July 27, ~~2014~~2023.

OnProposal ~~May 16,~~1 ~~2023,~~— ~~the~~Election ~~U.S. Federal Trade Commission (“FTC”) filed a complaint in the U.S. District Court for the Northern District~~ of ~~Illinois seeking a temporary restraining order and preliminary injunction enjoining the Acquisition~~directors. On May 17, 2023, the court granted a stipulated temporary restraining order (the “Initial Stipulated TRO”). Following a case management hearing, on May 24, 2023, the court scheduled an evidentiary hearing on the FTC’s request for a preliminary injunction beginning on September 11, 2023. Based on the court’s schedule, Horizon, Amgen and the FTC then jointly proposed an extension of the Initial Stipulated TRO to the earlier of October 31, 2023 or the second business day after the court rules on the FTC’s request for a preliminary injunction (the “Revised Stipulated TRO”). On June 2, 2023, the court issued an order granting the Revised Stipulated TRO. If the court denies the FTC’s request for a preliminary injunction on or before the October 31, 2023 date set forth in the Revised Stipulated TRO or the litigation is otherwise favorably resolved by that date, Horizon would expect the Acquisition to close by mid-December.

The following directors were elected to serve for three-year terms expiring at the 2026 Annual General Meeting of Shareholders and until their respective successors are duly elected and qualified, or, if sooner, until the respective director’s death, resignation, disqualification or removal.


Director Elected	For		Against		Abstain		Broker Non-Votes
Gino Santini		151,483,008		5,400,292		276,244		11,655,073
James Shannon, M.D.		131,479,967		25,396,734		282,843		11,655,073
Timothy P. Walbert		142,310,378		14,398,120		451,046		11,655,073

Proposal 2 — Approval of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2023 and the authorization of the Audit Committee of our Board of Directors to determine the auditors’ remuneration.


For	Against	Abstain	Broker Non-Votes
165,306,334	3,134,859	373,424	0

Proposal 3 — Approval, on an advisory basis, of the compensation of our named executive officers.


For	Against	Abstain	Broker Non-Votes
91,107,568	65,607,818	444,158	11,655,073

FURTHER INFORMATION

Statement Required by the Irish Takeover Rules

The directors of Horizon accept responsibility for the information contained in this report. To the best of the knowledge and belief of the directors of Horizon (who have taken all reasonable care to ensure that such is the case), the information contained in this report is in accordance with the facts and does not omit anything likely to affect the import of such information.

Cautionary Statement Regarding Forward-looking Statements

This report contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are often identified by words such as “anticipate,” “believe,” “intend,” “estimate,” “expect,” “see,” “continue,” “could,” “can,” “may,” “will,” “likely,” “depend,” “should,” “would,” “plan,” “predict,” “target,” and similar expressions, and may include references to assumptions and relate to Horizon’s future prospects, developments and business strategies, and the Acquisition. Such forward-looking statements include, but are not limited to, statements relating to the Acquisition, the FTC litigation and Horizon’s and Amgen’s expectations with respect to the timing of future events. Horizon’s expectations and beliefs regarding these matters may not materialize. Actual outcomes and results may differ materially from those contemplated by these forward-looking statements as a result of uncertainties, risks, and changes in circumstances, including but not limited to risks and uncertainties related to: whether Horizon and Amgen are successful in or otherwise able to resolve the FTC litigation; the time it takes to resolve the FTC litigation; the ability of the parties to consummate the Acquisition in a timely manner or at all; the possibility that the FTC litigation or any further inquires or actions from the FTC could have the effect of further delaying, imposing restrictions on, or impeding or precluding the completion of the Acquisition; the satisfaction (or waiver) of conditions to the consummation of the Acquisition; the occurrence of any event, change or other circumstance or condition that could give rise to the termination of the transaction agreement governing the Acquisition; and the outcome of any additional legal proceedings that have or may be instituted against the parties or any of their respective directors or officers related to the Acquisition. Additional risks and uncertainties that

could cause actual outcomes and results to differ materially from those contemplated by the forward-looking statements are included under the caption “Risk Factors” and elsewhere in Horizon’s most recent filings with the SEC, including its Annual Report on Form 10-K for the year ended December 31, 2022, and any subsequent reports on Form 10-Q or Form 8-K filed with the SEC from time to time and available at www.sec.gov. These documents can be accessed on Horizon’s website at https://ir.horizontherapeutics.com/financial-information/sec-filings. The forward-looking statements set out in this report are made only as of the date hereof. Horizon assumes no obligation and does not intend to update these forward-looking statements, except as required by law.

Dealing Disclosure Requirements

Under the provisions of Rule 8.3(b) of the Irish Takeover ~~Panel Act, 1997, Irish Takeover~~ Rules, ~~2022 (the “Irish Takeover Rules”),~~ if any person is, or becomes, ‘interested’ in 1% or more of any class of ‘relevant securities’ of ~~Horizon~~the Company, that person must publicly disclose all ‘dealings’ in any ‘relevant securities’ of ~~Horizon~~the Company during the ‘offer period’, by not later than 3:30 p.m. (E.T.) on the ‘business day’ following the date of the relevant transaction.

If two or more persons co-operate on the basis of any agreement either express or tacit, either oral or written, to acquire an ‘interest’ in ‘relevant securities’ of ~~Horizon~~the Company or any securities exchange offeror, they will be deemed to be a single person for the purpose of Rule 8.3 of the Irish Takeover Rules.

In addition, each of the Company and any offeror must make an ‘opening position disclosure’ by no later than 12:00 noon (E.T.) on the date falling ten ‘business days’ following the commencement of the ‘offer period’ or the announcement that first identifies a securities exchange offeror, as applicable, and disclose details of any ‘dealings’ by it or any person ‘acting in concert’ with it in ‘relevant securities’ during the ‘offer period’, by no later than 12:00 noon (E.T.) on the business day following the date of the transaction (see Rules 8.1, 8.2 and 8.4 of the Irish Takeover Rules).

A disclosure table, giving details of the companies in whose ‘relevant securities’ ‘opening position’ and ‘dealings’ should be disclosed can be found on the Irish Takeover Panel’s website at www.irishtakeoverpanel.ie.

‘Interests’ in securities arise, in summary, when a person has long economic exposure, whether conditional or absolute, to changes in the price of securities. In particular, a person will be treated as having an ‘interest’ by virtue of the ownership or control of securities, or by virtue of any option in respect of, or derivative referenced to, securities.

Terms in quotation marks are defined in the Irish Takeover Rules, which can be found on the Irish Takeover Panel’s website. If you are in any doubt as to whether or not you are required to disclose aan ‘opening position’ or ‘dealing’ under Rule 8 of the Irish Takeover Rules, please consult the Irish Takeover Panel’s website at www.irishtakeoverpanel.ie or contact the Irish Takeover Panel on telephone number +353 1 678 9020.

~~General~~Rounding

ACertain ~~copy~~figures ofincluded in this ~~announcement~~report ~~will~~have bebeen ~~available,~~subjected ~~free of charge (subject~~ to ~~certain~~rounding ~~restrictions~~adjustments. ~~relating~~Accordingly, toany ~~persons~~figures ~~resident~~shown infor ~~certain~~the ~~restricted~~same ~~jurisdictions)~~category onpresented ~~Horizon’s~~in ~~website~~different attables ~~https://ir.horizontherapeutics.com/information~~may byvary noslightly ~~later~~and ~~than~~figures ~~12:00~~shown ~~noon~~as ~~(E.T.)~~totals onin ~~the~~certain ~~business~~tables ~~day~~may ~~following~~not ~~this~~be ~~announcement~~an ~~and~~arithmetic ~~throughout~~aggregation ~~the course~~ of the ~~pending~~figures ~~transaction.~~that ~~Neither~~precede ~~the contents of Horizon’s website nor the contents of any other website accessible from hyperlinks are incorporated into, or form part of, this announcement~~them.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date: June 5, 2023

HORIZON THERAPEUTICS PUBLIC LIMITED COMPANY

Date: July 28, 2023

HORIZON THERAPEUTICS PUBLIC LIMITED COMPANY

/s/ Aaron L. Cox

Aaron L. Cox

Executive Vice President and Chief Financial Officer

Filing Compare · Horizon Therapeutics Public Ltd Co