UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of ~~the~~Report ~~Securities~~(Date ~~Exchange~~of ~~Act~~earliest ofevent ~~1934~~reported): December 1, 2020 (December 1, 2020)

~~Date~~Nuveen ofTax-Advantaged ~~Report~~Total ~~(Date~~Return ofStrategy ~~earliest~~Fund ~~event reported): October 5, 2020 (October 5, 2020)~~

NUVEEN TAX-ADVANTAGED TOTAL RETURN STRATEGY FUND

(Exact name of registrant as specified in its charter)

Massachusetts	811-21471	20-0591876
(State or other jurisdiction of incorporation)	(~~Commission~~CommissionFile ~~File~~ Number)	(I.R.S. Employer Identification No.)
333 West Wacker DriveChicago, Illinois		60606
(Address of principal executive offices)		(Zip Code)

333 West Wacker Drive Chicago, Illinois		60606
(Address of principal executive offices)		(Zip Code)

Registrant’s telephone number, including area code: (800) 257-8787

(Former name or former address, if changed since last report): N/A

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐	Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐	Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d- 2(b))

☐ Pre-commencement communications pursuant to Rule ~~13e~~20e-4(c) under the Exchange Act (17 CFR 240.1320e-4(c))

Securities registered ~~or to be registered~~ pursuant to Section 12(b) of the Act.:

Title of each class Trading ~~Symbol~~symbol(s) Name of ~~each~~ exchange onof which registered Common ~~Stock~~Shares of Beneficial Interest JTA New York Stock Exchange

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 78.01. ~~Regulation~~Other ~~FD Disclosure~~Events.

~~Amended and Restated By-Laws.~~ On ~~October~~December 51, 2020, the Board of Trustees of Nuveen Tax-Advantaged Total Return Strategy Fund (NYSE: JTA), a registered closed-end management investment company (the “Fund”), ~~amended~~announced ~~and~~the ~~restated~~approval inof ~~its~~a ~~entirety~~new ~~the~~sub-advisory agreement between Nuveen Fund ~~Amended~~Advisors, ~~and~~LLC ~~Restated~~(“Nuveen ~~By-Laws~~Fund ofAdvisors”), the Fund’s ~~(the~~investment ~~“Amended~~adviser, and ~~Restated~~Nuveen ~~By-Laws~~Asset Management, LLC (“NAM”). The ~~Amended~~new ~~and~~sub-advisory ~~Restated~~agreement Bywas approved in connection with the forthcoming merger of the Fund’s current sub-~~Laws~~adviser, Symphony Asset Management LLC (“Symphony”), with and into NAM, which is currently scheduled to close on December 31, 2020. Symphony and NAM are ~~attached~~both ~~hereto~~affiliates asof ~~Exhibit~~Nuveen ~~3.1~~Fund Advisors and all are ~~incorporated~~subsidiaries ~~herein~~of byNuveen, ~~reference~~LLC. The new sub-advisory agreement will become effective upon the close of the merger.

OnThe ~~October 5,~~terms ~~2020,~~of the ~~Fund~~new ~~issued~~sub-advisory aagreement ~~press~~with ~~release~~NAM ~~in connection~~are substantially identical to the current sub-advisory agreement with Symphony. NAM will provide the ~~adoption~~same level of services to the ~~Amended~~Fund, ~~and~~with ~~Restated~~the ~~By-Laws~~Symphony personnel who currently serve as portfolio managers of the Fund continuing to do so as NAM personnel. In addition, this change will not impact the Fund’s fees, investment objectives or policies.

~~Item~~SIGNATURES ~~9.01 Financial Statements and Exhibits.~~

(d)		Exhibits
3.1		Amended and Restated By-Laws
99.1		Press Release, dated October 5, 2020

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.


				NUVEEN TAX-ADVANTAGED TOTAL RETURN STRATEGY FUND

Date: December 1, 2020				By: /s/ Mark L. Winget

				Mark L. Winget
				Vice President and Secretary

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

NUVEEN TAX-ADVANTAGED TOTAL RETURN STRATEGY FUND By: /s/ Gifford R. Zimmerman Name: Gifford R. Zimmerman Title: Vice President and Secretary

DATE: October 5, 2020

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