UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

~~January~~June 2419, 2008

Date of Report (Date of earliest event reported)

APPLERA CORPORATION

(Exact ~~name~~Name of ~~registrant~~ Registrant as ~~specified~~Specified in ~~its charter~~ Charter)

Delaware		001-04389		06-1534213
(State or other jurisdiction of incorporation)		(Commission File Number)		(IRS Employer Identification No.)

301 Merritt 7 Norwalk, Connecticut		06851
(Address of principal executive offices)		(Zip Code)

(203) 840-2000 (Registrant’s telephone number, including area code) N/A (Former name or former address, if changed since last report)

(Registrant’s telephone number, including area code)

N/A

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨ o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨ o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨ o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2 (b))

¨ o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4 (c))

Item 25.0203. ~~Results~~Amendments to Articles of ~~Operations~~Incorporation ~~and~~or ~~Financial~~Bylaws; ~~Condition~~Change in Fiscal Year.

~~(a)~~ On ~~January~~June 2419, 2008, ~~Applera Corporation (“Applera”) announced financial results for Applera and its business units for~~ the ~~second~~Board ~~quarter~~ of ~~its~~Directors ~~2008~~of ~~fiscal~~Applera ~~year. Attached~~Corporation ~~hereto as Exhibit 99.1 and incorporated by reference herein is~~ (the ~~text~~“Company”) ofapproved aamendments ~~press release issued on January 24~~(collectively, ~~2008,~~the ~~with~~“Amendment”) ~~respect~~ to ~~financial results for the second quarter of fiscal year 2008 of Applera and Applera’s Applied Biosystems~~Section 8 ~~Group, and attached hereto as Exhibit 99.2 and incorporated by reference herein is the text~~ of ~~a press release issued on January 24, 2008, with respect to financial results for~~ the ~~second quarter of fiscal year 2008 of Applera and Applera~~Company’s ~~Celera~~By-laws, ~~Group.~~effective immediately.

~~Item~~Pursuant 9to the Amendment, Section 8 of the Company’s By-laws has been revised to clarify that stockholders must comply with the advance notice provision therein in order to propose any business at annual meetings.01 The Amendment further provides that, in order to be timely, a stockholder’s notice must be delivered to the Company not less than 90 nor more than 120 days prior to the anniversary date of the immediately preceding annual meeting of stockholders. Section 8 ~~Financial~~of ~~Statements~~the ~~and~~Company’s ~~Exhibits~~By-laws formerly provided that a stockholder’s notice be delivered to the Company not less than 45 nor more than 75 days before the anniversary of the date on which the Company first mailed its proxy materials for the preceding year’s annual meeting. In addition, the Amendment also deletes reference to Rule 14a-8 under the Securities Exchange Act of 1934, as amended. The Amendment also adds a requirement that a stockholder who makes a proposal or nominates a director must disclose any short position or hedging arrangement that he or his nominee has with respect to the Company’s common stock.

~~(d) Exhibits~~Item 9.01. Financial Statement and Exhibits.

~~The following exhibits are filed with this Report:~~ (d) Exhibits.

Exhibit No.		Description
99.1		Press Release issued January 24, 2008, with respect to financial results for Applera and Applera’s Applied Biosystems Group.
99.2		Press Release issued January 24, 2008, with respect to financial results for Applera and Applera’s Celera Group.

The following exhibits are filed with this Report:

SIGNATURES

Exhibit No.		Description

3.1		By-laws of Applera Corporation, as amended through June 19, 2008

~~Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.~~ 2

~~APPLERA CORPORATION By: /s/ Dennis L. Winger Dennis L. Winger Senior Vice President and Chief Financial Officer~~SIGNATURES

~~Dated:~~Pursuant ~~January 24~~to the requirements of the Securities Exchange Act of 1934, ~~2008~~the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

EXHIBIT INDEX

	APPLERA CORPORATION


	By:	/s/ Thomas P. Livingston
		Thomas P. Livingston
		Vice President and Secretary
Date: June 19, 2008

Exhibit No.		Description
99.1		Press Release issued January 24, 2008, with respect to financial results for Applera and Applera’s Applied Biosystems Group.
99.2		Press Release issued January 24, 2008, with respect to financial results for Applera and Applera’s Celera Group.

EXHIBIT INDEX

Exhibit No.		Description

3.1		By-laws of Applera Corporation, as amended through June 19, 2008

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