UNITED STATES ~~SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549~~

~~FORM 8-K~~SECURITIES AND EXCHANGE COMMISSION

CURRENTWashington, REPORTDC 20549

~~Pursuant~~FORM ~~to Section 13 or 15(d) of the Securities Exchange Act of 1934~~8-K

~~Date~~CURRENT ~~of Report (Date of earliest event reported): August 22, 2005~~REPORT

~~VWR~~PURSUANT ~~INTERNATIONAL, INC.~~TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

~~(Exact~~Date ~~name~~ of ~~registrant~~report ~~as specified~~(Date inof ~~its~~earliest ~~charter~~event reported): January 11, 2006

~~Delaware~~VWR ~~(State~~International, ~~or other jurisdiction of incorporation) 333-118658 (Commission File Number) 91-1319190 (I~~Inc.~~R.S. Employer Identification No.)~~

~~1310 Goshen Parkway P.O. Box 2656 West Chester, PA 19380~~ (~~Address~~Exact name of ~~principal executive~~registrant ~~offices,~~as ~~including~~specified ~~zip~~in ~~code~~its charter)

(Registrant’s telephone number, including area code): (610) 431-1700

DELAWARE	333-118658	91-1319190
(State or other jurisdiction of	(Commission	I.R.S. Employer
incorporation or organization)	File Number)	Identification No.)

1310 Goshen Parkway
P.O. Box 2656
West Chester, PA		19380
(Address of principal executive offices)		(Zip Code)

~~Check~~(610) ~~the appropriate box below if the Form 8~~431-K1700 ~~filing~~(Registrant’s istelephone ~~intended~~number, toincluding ~~simultaneously satisfy~~area ~~the~~code) ~~filing~~None ~~obligation~~(Former ofname, ~~the~~former ~~registrant~~address ~~under~~and ~~any~~former offiscal ~~the~~year, ~~following provisions~~if ~~(see~~changed ~~General~~since ~~Instructions~~last ~~A.2. below~~report):

~~o Written~~Check ~~communications~~the ~~pursuant~~appropriate box below if the Form 8-K filing is intended to ~~Rule~~simultaneously satisfy ~~425~~the ~~under~~filing obligation of the ~~Securities~~registrant ~~Act~~under any of the following provisions (17see ~~CFR~~General ~~230~~Instruction A.~~425~~2. below):

o ~~Soliciting material~~Written communications pursuant to Rule ~~14a-12~~ 425 under the ~~Exchange~~Securities Act (17 CFR ~~240~~230.~~14a-12~~425)

o ~~Pre-commencement communications~~Soliciting material pursuant to Rule ~~14d~~ 14a-~~2(b)~~12 under the Exchange Act (17 CFR 240.~~14d~~14a-~~2(b~~12))

o Pre-commencement communications pursuant to Rule ~~13e~~ 14d-42(cb) under the Exchange Act (17 CFR 240.~~13e~~14d-42(cb))

~~ITEM~~o Pre-commencement ~~2.02~~communications ~~RESULTS~~pursuant OFto Rule 13e-4(c) ~~OPERATIONS~~under ~~AND~~the ~~FINANCIAL~~Exchange ~~CONDITION~~Act (17 CFR 240.13e-4(c))

~~ITEM~~Item 71.01 ~~REGULATION~~Entry FDinto ~~DISCLOSURE~~a Material Definitive Agreement.

~~The~~VWR International, Inc. ~~information~~(the in“Company”) ~~this~~entered ~~schedule is being~~into ~~furnished~~an inAgreement ~~accordance~~(the ~~with~~“Agreement”), effective ~~Regulation~~as FDof ~~and~~January 10, ~~not~~2006, ~~“filed”~~by ~~with~~and between the ~~Securities~~ Company and ~~Exchange~~Edward ~~Commission.~~ Orzetti ~~Accordingly,~~outlining ~~such~~the ~~information~~details isof ~~not~~Mr. ~~incorporated~~Orzetti’s byresignation ~~reference~~from ~~into~~his ~~any~~position as the Company’s ~~registration~~President, ~~statement~~Global ~~filed~~Lab byBusiness, ~~VWR~~effective ~~International~~February 28, ~~Inc~~ 2006. The ~~(the~~Agreement ~~“Company”)~~provides Mr. Orzetti with certain ~~under~~benefits ~~the~~related ~~Securites~~to ~~Act~~his resignation of ~~1933,~~employment asincluding ~~amended~~a lump sum severance payment equal to $550,000, ~~and~~continued ~~will~~health ~~not~~and bedental sobenefits ~~incorporated~~until byAugust ~~reference~~31, ~~into~~2006, ~~any~~COBRA ~~future~~benefit ~~registration~~continuation, ~~statement~~the ~~unless~~repurchase ~~specifically~~of previously acquired shares, ~~indentified~~and asaccelerated ~~being~~vesting ~~incorporated~~of byoptions ~~reference~~in CDRV Investors, Inc., the Company’s indirect parent.

OnThe ~~August~~Agreement ~~23,~~also ~~2005,~~contains ~~the~~customary ~~Company will~~non-competition ~~conduct an investor conference call to discuss second quarter 2005 earnings~~ and ~~an outlook for 2005.~~ ~~Management’s presentation will contain certain~~ non-~~GAAP~~solicitation ~~financial measures. The~~restrictions ~~following~~that ~~table~~will ~~sets~~apply ~~forth the calculation of Credit Agreement EBITDA~~ for ~~each~~one ofyear ~~the~~following ~~periods presented~~Mr. ~~Credit Agreement EBITDA as presented herein is a financial measure that is used in the credit agreement for the Company~~Orzetti’s ~~Senior Secured Credit Facility. Credit Agreement EBITDA is a non-GAAP financial measure. Accordingly~~resignation, ~~the~~and ~~table presented~~an ~~below~~indefinite ~~reconciles~~restriction ~~Credit~~on ~~Agreement EBITDA to~~ the ~~most~~disclosure ~~comparable GAAP~~of ~~measure~~confidential ~~presented in the Company’s financial statements as filed in its periodic reports~~information. ~~This table also includes a projection of Credit Agreement EBITDA for the year ending December 31, 2005.~~

~~Credit Agreement EBITDA should~~The ~~not~~description beof ~~considered~~the asAgreement anset ~~alternative~~forth toabove ~~net~~is ~~income~~qualified orin ~~any~~its ~~other~~entirety ~~GAAP measure of~~by ~~performance~~reference orto ~~liquidity. As specified in~~ the ~~table~~actual ~~and~~terms ~~accompanying~~of ~~notes, Credit Agreement EBITDA eliminates~~ the ~~effect of charges primarily associated with financing decisions~~Agreement, ~~tax~~which ~~regulations,~~is ~~capital~~attached ~~investments;~~hereto ~~and~~as ~~certain~~Exhibit 99.1 ~~non-cash~~ and ~~extraordinary, unusual or non-recurring items. Accordingly, Credit Agreement EBITDA~~ is aincorporated ~~key~~herein ~~financial metric used~~ by ~~the~~this ~~Company’s investors to evaluate and measure VWR International’s operating performance and adherence to certain covenant ratio tests~~reference.

~~Credit~~Item ~~Agreement~~9.01 ~~EBITDA~~Financial ~~(US~~Statements ~~dollars~~and ~~in millions)~~Exhibits.

												Projected Credit Agreement
	12 Months Ended June 30, 2005											EBITDA for the
	Q3 2004			Q4 2004		Q1 2005		Q2 2005		Total		Year Ending December 31, 2005
Net income	$	13.6		$	9.8	$	5.1	$	9.2	$	37.7	$	47.2
Income tax provision	11.8			4.9		3.2		6.0		25.9		30.3
Interest expense, net	16.9			17.9		17.8		18.4		71.0		73.0
Depreciation and amortization	8.7			9.0		8.4		8.5		34.6		33.9
Non-cash charges (1)	(2.7		)	3.0		4.2		2.8		7.3		12.6
Other extraordinary, unusual or non-recurring items (2)	0.4			—		2.1		5.1		7.6		7.2
Adjustment for pro-forma effect of material acquisitions (3)	1.4			1.1		0.8		—		3.3		0.8
Credit Agreement EBITDA	$	50.1		$	45.7	$	41.6	$	50.0	$	187.4	$	205.0

~~(1) Non-cash~~See ~~charges~~Exhibit Index include pension, postretirement and post employment benefit expenses, net of cash contributed to the respective plans in that year; amortization of direct response catalog costs for those catalogs with useful lives greater than one year; and LIFO adjustmentsbelow.

(2) Other extraordinary, unusual or non-recurring items include one-time severance costs; non-routine inventory reserve adjustments; gains or losses on the sale of businesses or facilities; and other extraordinary, unusual or non-recurring gains, losses, charges or credits.SIGNATURES

~~(3) Adjustment~~Pursuant ~~for~~to ~~pro-forma~~the ~~effect~~requirements of ~~material~~the ~~acquisitions,~~Securities asExchange ~~defined,~~Act isof ~~reflected~~1934, in the registrant has ~~calculation~~duly ofcaused ~~Credit~~this ~~Agreement~~report ~~EBITDA~~to onbe asigned ~~pro-forma~~on ~~basis~~its asbehalf ifby the ~~acquisitions~~ ofundersigned ~~AGB Scientific Ltd. and Advanced Instruments Sales &~~hereunto ~~Service,~~duly ~~Inc~~authorized. ~~occurred on July 1, 2004.~~

This Interim Report on Form 8-K includes forward-looking statements regarding our projected financial results for the year ending December 31, 2005. These statements are forward-looking statements as defined in Section 21E of the Securities Exchange Act of 1934. These statements are subject to risks and uncertainties that could cause our actual results to differ materially from those projected in these forward-looking statements. Factors that could cause actual results to differ materially from those in these forward-looking statements include: actions by manufacturers, customers, carriers and other third parties; our ability to maintain our relationships with manufacturers; loss of our key executive officers; our ability to consummate and integrate potential acquisitions; the effect of political and economic conditions, inflation and interest rates worldwide; the effect of changes in laws and regulations, including changes in accounting standards, trade, tax, price controls and other regulatory matters; and increased competition from other companies in our industry and our ability to retain or increase our market shares in our principal geographical markets. We undertake no obligation to publicly update or revise these forward-looking statements, whether as a result of new information, future events or otherwise.

	VWR INTERNATIONAL, INC.

Dated: January 11, 2006	By: /s/ Jack L. Wyszomierski

	Name:	Jack L. Wyszomierski
	Title:	Executive Vice President and Chief Financial Officer

~~SIGNATURES~~EXHIBIT INDEX

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

Exhibit No.		Description
99.1		Letter Agreement, among VWR International Inc. and Edward Orzetti.

	VWR INTERNATIONAL, INC.
Date: August 22, 2005	By:	/s/ STEPHEN KUNST
		Name: Stephen Kunst
		Title: Senior Vice President, General Counsel and Secretary

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