~~Table~~UNITED ofSTATES SECURITIES ~~Contents~~AND EXCHANGE COMMISSION

~~SECURITIES~~WASHINGTON, ~~AND~~D.C. ~~EXCHANGE COMMISSION~~20549

~~Washington, D.C. 20549~~_______________________

FORM 8-K

CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

~~Pursuant~~Date toof ~~Section 13~~Report ~~or 15~~(d)Date of ~~the~~ earliest event reported): November 21, 2005

~~Securities Exchange Act of 1934~~_______________________

~~Date of Report~~CYGNUS, ~~(Date of earliest event reported)~~INC.

~~October 17,~~(Exact ~~2005~~Name of Registrant as Specified in Its Charter)

~~CYGNUS,~~Delaware ~~INC~~(State or Other Jurisdiction of Incorporation) 0-18962 (Commission File Number) 94-2978092 (IRS Employer Identification No. )

~~(Exact~~88 ~~name~~Kearny Street, 4th Floor, San Francisco, California (Address of ~~registrant~~Principal asExecutive ~~specified~~Offices) in94108 ~~its~~(Zip ~~charter~~Code)

Delaware	0-18962	94-2978092
(State of incorporation)	(Commission File Number)	(IRS Employer
		Identification No.)

Registrant’s Telephone Number, including area code: (415) 392-6220

88 Kearny Street, 4th Floor		94108
San Francisco, California		(Zip Code)
(Address of principal executive offices)

N/A
(Former name or Former Address, if Changed Since Last Report)

~~(415) 392~~ Check the appropriate box below if the Form 8-~~6220 (Registrant’s~~K ~~telephone~~filing ~~number,~~is intended to simultaneously ~~including~~satisfy ~~area~~the ~~code~~filing obligation of the registrant under any of the following provisions (see General Instruction A.2):

~~N/A~~ o Written communications pursuant to Rule 425 under the Securities Act (~~Former~~17 ~~name~~CFR or230.425) ~~Former~~o ~~Address,~~Soliciting ifmaterial ~~Changed~~pursuant ~~Since~~to ~~Last~~Rule ~~Report~~14a-12 under the Exchange Act (17 CFR 240.14a-12) o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (7 CFR 240.13e-4(c))

~~Check the appropriate box below if the Form~~ Item 8-K.01. ~~filing~~Other ~~is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A~~Events.~~2):~~

o On ~~Written~~November 21, ~~communications~~2005, Cygnus, Inc. (“Cygnus”) filed its Certificate of Dissolution with the Secretary of State of Delaware pursuant to ~~Rule~~the Plan of Complete Liquidation and Dissolution adopted by its Board of Directors on December ~~425~~16, ~~under~~2004 and approved by its stockholders on March 23, 2005. As of the ~~Securities~~close ~~Act~~of business on November 21, 2005, Cygnus closed its stock transfer books and no ~~(17~~further ~~CFR~~stock ~~230~~transfers will be recognized.~~425)~~ Trading of Cygnus’ common stock on the OTC Bulletin Board has also ceased.

o There ~~Soliciting~~were ~~material~~41,759,251 ~~pursuant~~shares toof ~~Rule 14a-12~~Cygnus ~~under~~common stock outstanding as of the ~~Exchange~~close ~~Act (17~~of ~~CFR~~business ~~240~~on November 21, 2005.~~14a-12)~~

o Cygnus ~~Pre-commencement~~anticipates ~~communications~~making ~~pursuant~~its first liquidating distribution on or about December 15, 2005 to stockholders ~~Rule~~of record as of November ~~14d-2(b)~~21, ~~under~~2005, upon the ~~Exchange~~surrender ~~Act~~of ~~(17~~stock ~~CFR~~certificates, ~~240~~absent any unforeseen circumstances.~~14d-2(b))~~ On or about December 15, 2005, Cygnus expects to initiate a mailing to stockholders explaining the procedures for surrendering their stock certificates in order to receive payment.

~~o Pre~~-~~commencement communications pursuant to Rule 13e~~2-~~4(c) under the~~ ~~Exchange Act (7 CFR 240.13e-4(c))~~

~~TABLE OF CONTENTS~~SIGNATURES

~~Item~~ Pursuant ~~1.01. Entry into a Material Definitive Agreement Item 3.03 Material Modifications~~ to ~~Rights~~the requirements of ~~Security~~the ~~Holders~~Securities ~~Item~~Exchange ~~5.03~~Act ~~Amendments to Articles~~ of ~~Incorporation~~1934, orthe ~~Bylaws;~~registrant ~~Change~~has induly caused ~~Fiscal~~this ~~Year~~report ~~Item~~to ~~9.01.~~be ~~Financial~~signed ~~Statements~~on ~~and~~its ~~Exhibits~~behalf ~~SIGNATURE~~by ~~EXHIBIT~~the ~~INDEX~~undersigned ~~EXHIBIT~~hereunto ~~4.1~~duly ~~EXHIBIT 99~~authorized.2


	CYGNUS, INC.
Date: November 21, 2005	By:	/s/ Barbara G. McClung
		Barbara G. McClung
		Chief Legal Officer and Corporate Secretary

~~Item 1.01. Entry into a Material Definitive Agreement.~~-3-

On October 17, 2005, the Board of Directors of Cygnus, Inc. (the “Company”) declared a dividend of one preferred share purchase right (a “Right”) for each outstanding share of Common Stock, par value $0.001 per share (the “Common Shares”) outstanding on October 24, 2005 (the “Record Date”) to the stockholders of record on that date. Each Right entitles the registered holder to purchase from the Company one one-thousandth of a share of Series A Junior Participating Preferred Stock, par value $0.001 per share (the “Preferred Shares”), of the Company, at a price of $0.75 per one one-thousandth of a Preferred Share (the “Purchase Price”), subject to adjustment. The description and terms of the Rights are set forth in a Rights Agreement (the “Rights Agreement”) between the Company and Mellon Investor Services LLC, as Rights Agent (the “Rights Agent”). The Rights Agreement is effective immediately.

Until the earlier to occur of (i) 10 days following a public announcement that a person or group of affiliated or associated persons has acquired beneficial ownership of 4.95% or more of the outstanding Common Shares (or 12.5% in the case of any Person or member of a group of Persons that have filed a Schedule 13D with the Securities and Exchange Commission prior to the date of the adoption of the Rights Agreement (any such Person or member, “Grandfathered Stockholders”) or an Affiliate or Associate of a Grandfathered Stockholder who or which would also be an Acquiring Person due solely to such affiliation or association when considered together with the Grandfathered Stockholder such Person is associated or affiliated with) (any such Person, an “Acquiring Person”) or (ii) 10 business days (or such later date as may be determined by action of the Board of Directors prior to such time as any Person becomes an Acquiring Person) following the commencement of, or announcement of an intention to make, a tender offer or exchange offer the consummation of which would result in any Person becoming an Acquiring Person (the earlier of such dates being called the “Distribution Date”), the Rights will be evidenced, with respect to any of the Common Share certificates outstanding as of the Record Date, by such Common Share certificate with a copy of the Summary of Rights attached thereto.

The Rights Agreement provides that, until the Distribution Date, the Rights will be transferred with and only with the Common Shares. Until the Distribution Date (or earlier redemption or expiration of the Rights), new Common Share certificates issued after the Record Date or upon transfer or new issuance of Common Shares will contain a notation incorporating the Rights Agreement by reference. Until the Distribution Date (or earlier redemption or expiration of the Rights), the surrender for transfer of any certificates for Common Shares outstanding as of the Record Date, even without such notation or a copy of this Summary of Rights being attached thereto, will also constitute the transfer of the Rights associated with the Common Shares represented by such certificate. As soon as practicable following the Distribution Date, separate certificates evidencing the Rights (“Right Certificates”) will be mailed to holders of record of the Common Shares as of the Close of Business on the Distribution Date and such separate Right Certificates alone will evidence the Rights.

The Rights are not exercisable until the Distribution Date. The Rights will expire on October 17, 2015 (the “Final Expiration Date”), unless the Final Expiration Date is extended or unless the Rights are earlier redeemed by the Company, in each case, as described below.

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The Purchase Price payable, and the number of Preferred Shares or other securities or property issuable, upon exercise of the Rights are subject to adjustment from time to time to prevent dilution (i) in the event of a stock dividend on, or a subdivision, combination or reclassification of, the Preferred Shares, (ii) upon the grant to holders of the Preferred Shares of certain rights or warrants to subscribe for or purchase Preferred Shares at a price, or securities convertible into Preferred Shares with a conversion price, less than the then current market price of the Preferred Shares or (iii) upon the distribution to holders of the Preferred Shares of evidences of indebtedness or assets (excluding regular periodic cash dividends paid out of earnings or retained earnings or dividends payable in Preferred Shares) or of subscription rights or warrants (other than those referred to above).

The number of outstanding Rights and the number of one one-thousandths of a Preferred Share issuable upon exercise of each Right are also subject to adjustment in the event of a stock split of the Common Shares or a stock dividend on the Common Shares payable in Common Shares or subdivisions, consolidations or combinations of the Common Shares occurring, in any such case, prior to the Distribution Date.

Preferred Shares purchasable upon exercise of the Rights will not be redeemable. Each Preferred Share will be entitled to a quarterly dividend payment of 1,000 times the dividend declared per Common Share. In the event of liquidation, the holders of the Preferred Shares will be entitled to an aggregate payment of 1,000 times the aggregate payment made per Common Share. Each Preferred Share will have 1,000 votes, voting together with the Common Shares. In the event of any merger, consolidation or other transaction in which Common Shares are exchanged, each Preferred Share will be entitled to receive 1,000 times the amount received per Common Share. These rights are protected by customary antidilution provisions.

Because of the nature of the Preferred Shares’ dividend, liquidation and voting rights, the value of the one one-thousandth interest in a Preferred Share purchasable upon exercise of each Right should approximate the value of one Common Share.

From and after the time any Person becomes an Acquiring Person, if the Rights evidenced by a Right Certificate are or were at any time on or after the earlier of (x) the date of such event and (y) the Distribution Date (as such term is defined in the Rights Agreement) acquired or beneficially owned by an Acquiring Person or an Associate or Affiliate of an Acquiring Person (as such terms are defined in the Rights Agreement), such Rights shall become void, and any holder of such Rights shall thereafter have no right to exercise such Rights.

In the event that, at any time after a Person becomes an Acquiring Person, the Company is acquired in a merger or other business combination transaction or 50% or more of its consolidated assets or earning power are sold, proper provision will be made so that each holder of a Right will thereafter have the right to receive, upon the exercise thereof at the then current exercise price of the Right, that number of shares of common stock of the acquiring company which at the time of such transaction will have a market value of two times the exercise price of the Right. In the event that any person becomes an Acquiring Person, proper provision shall be made so that each holder of a Right, other than Rights beneficially owned by the Acquiring Person and its Affiliates and Associates (which will thereafter be void), will thereafter have the right to receive upon exercise that number of Common Shares having a market value of

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two times the exercise price of the Right. If the Company does not have sufficient Common Shares to satisfy such obligation to issue Common Shares, or if the Board of Directors so elects, the Company shall deliver upon payment of the exercise price of a Right an amount of cash or securities equivalent in value to the Common Shares issuable upon exercise of a Right; provided that, if the Company fails to meet such obligation within 30 days following the date a Person becomes an Acquiring Person, the Company must deliver, upon exercise of a Right but without requiring payment of the exercise price then in effect, Common Shares (to the extent available) and cash equal in value to the difference between the value of the Common Shares otherwise issuable upon the exercise of a Right and the exercise price then in effect. The Board of Directors may extend the 30-day period described above for up to an additional 60 days to permit the taking of action that may be necessary to authorize sufficient additional Common Shares to permit the issuance of Common Shares upon the exercise in full of the Rights.

At any time after any Person becomes an Acquiring Person and prior to the acquisition by any person or group of a majority of the outstanding Common Shares, the Board of Directors of the Company may exchange the Rights (other than Rights owned by such person or group which have become void), in whole or in part, at an exchange ratio of one Common Share per Right (subject to adjustment).

With certain exceptions, no adjustment in the Purchase Price will be required until cumulative adjustments require an adjustment of at least 1% in such Purchase Price. No fractional Preferred Shares will be issued (other than fractions which are integral multiples of one one-thousandth of a Preferred Share, which may, at the election of the Company, be evidenced by depositary receipts) and in lieu thereof, an adjustment in cash will be made based on the market price of the Preferred Shares on the last trading day prior to the date of exercise.

At any time prior to the time any Person becomes an Acquiring Person, the Board of Directors of the Company may redeem the Rights in whole, but not in part, at a price of $0.001 per Right (the “Redemption Price”). The redemption of the Rights may be made effective at such time, on such basis and with such conditions as the Board of Directors in its sole discretion may establish. Immediately upon any redemption of the Rights, the right to exercise the Rights will terminate and the only right of the holders of Rights will be to receive the Redemption Price.

The terms of the Rights may be amended by the Board of Directors of the Company without the consent of the holders of the Rights, except that from and after such time as any person becomes an Acquiring Person after the close of business on the date of adoption of the Rights Agreement no such amendment may adversely affect the interests of the holders of the Rights (other than the Acquiring Person and its Affiliates and Associates).

Until a Right is exercised, the holder thereof, as such, will have no rights as a stockholder of the Company, including, without limitation, the right to vote or to receive dividends.

As of October 17, 2005, there were 41,009,251 shares of common stock outstanding and 5,342,679 shares of common stock reserved for the exercise of outstanding stock options and warrants. Each outstanding share of Common Stock on the Record Date will receive

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one Right. Shares of Common Stock issued after the Record Date and prior to the Distribution Date will be issued with a Right attached so that all shares of Common Stock outstanding prior to the Distribution Date will have Rights attached. 95,000 shares of Preferred Stock have been reserved for issuance upon exercise of the Rights.

The Rights have certain anti-takeover effects. The Rights may cause substantial dilution to a person that attempts to acquire the Company without a condition to such an offer that a substantial number of the Rights be acquired or that the Rights be redeemed or declared invalid. The Rights should not interfere with any merger or other business combination approved by the Board of Directors since the Rights may be redeemed by the Company as described above.

This summary description of the Rights does not purport to be complete and is qualified in its entirety by reference to the Agreement, which is attached hereto as Exhibit 4.1 and hereby incorporated herein by reference.

The Company also engages Mellon Investor Services LLC as its transfer agent .

Item 3.03 Material Modifications to Rights of Security Holders

See the description set forth under “Item 1.01 Entry into a Material Definitive Agreement,” which is incorporated into this Item 3.03 by reference.

Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year

On October 17, 2005, the Company filed a Certificate of Designation of Series A Junior Participating Preferred Stock with the Secretary of State of the State of Delaware. See the description set out under “Item 1.01 Entry into a Material Definitive Agreement” for a more complete description of the rights and preferences of the Series A Junior Participating Preferred Stock. A copy of the Certificate of Designation of Series A Junior Participating Preferred Stock is attached as Exhibit 3.1 to this Current Report on Form 8-K and incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.

Exhibit No.		Description
3.1		Certificate of Designation of Series A Junior Participating Preferred Stock, included as Exhibit A to Exhibit 4.1.
4.1		Rights Agreement, dated as of October 17, 2005, between Cygnus, Inc. and Mellon Investor Services LLC, which includes: as Exhibit A thereto, the Certificate of Designation of Series A Junior Participating Preferred Stock; as Exhibit B thereto, the Form of Right Certificate; as Exhibit C thereto, the Summary of Rights to Purchase Preferred Shares.

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Exhibit No.		Description
4.2		Form of Right Certificate, included as Exhibit B to Exhibit 4.1.
99.1		Summary of Rights to Purchase Preferred Shares, included as Exhibit C to Exhibit 4.1.
99.2		Press release, relating to adoption of Rights Agreement, dated October 17, 2005, issued by the Company.

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SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized.

CYGNUS, INC. By: /s/ Barbara G. McClung Barbara G. McClung Chief Legal Officer and Corporate Secretary

Dated: October 17, 2005

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EXHIBIT INDEX

Exhibit		Description
3.1		Certificate of Designation of Series A Junior Participating Preferred Stock, included as Exhibit A to Exhibit 4.1.
4.1		Rights Agreement, dated as of October 17, 2005, between Cygnus, Inc. and Mellon Investor Services LLC, which includes: as Exhibit A thereto, the Certificate of Designation of Series A Junior Participating Preferred Stock; as Exhibit B thereto, the Form of Right Certificate; as Exhibit C thereto, the Summary of Rights to Purchase Preferred Shares.
4.2		Form of Right Certificate, included as Exhibit B to Exhibit 4.1.
99.1		Summary of Rights to Purchase Preferred Shares, included as Exhibit C to Exhibit 4.1.
99.2		Press release, relating to adoption of Rights Agreement, dated October 17, 2005, issued by the Company.

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