SIGNAL PHARMACEUTICALS INC S-1

FORM S-1

EXHIBIT 3.1

EXHIBIT 3.2

EXHIBIT 10.1

EXHIBIT 10.2

EXHIBIT 10.3

EXHIBIT 10.4

EXHIBIT 10.5

EXHIBIT 10.6

EXHIBIT 10.7

EXHIBIT 10.8

EXHIBIT 10.9

EXHIBIT 10.10

EXHIBIT 10.11

EXHIBIT 10.12

EXHIBIT 10.13

EXHIBIT 10.14

EXHIBIT 10.15

EXHIBIT 10.16

EXHIBIT 10.17

EXHIBIT 10.18

EXHIBIT 10.19

EXHIBIT 10.20

EXHIBIT 10.21

EXHIBIT 10.22

EXHIBIT 10.23

EXHIBIT 10.24

EXHIBIT 10.25

EXHIBIT 10.26

EXHIBIT 10.27

EXHIBIT 10.28

EXHIBIT 10.29

EXHIBIT 10.30

EXHIBIT 10.31

EXHIBIT 10.32

EXHIBIT 10.33

EXHIBIT 10.34

EXHIBIT 10.35

EXHIBIT 10.36

EXHIBIT 10.37

EXHIBIT 10.38

EXHIBIT 10.39

EXHIBIT 10.40

EXHIBIT 10.41

EXHIBIT 10.43

EXHIBIT 10.44

EXHIBIT 10.45

EXHIBIT 10.46

EXHIBIT 10.47

EXHIBIT 10.48

EXHIBIT 10.49

EXHIBIT 10.50

EXHIBIT 10.51

EXHIBIT 10.52

EXHIBIT 11.1

EXHIBIT 23.1

FINANCIAL DATA SCHEDULE